Ki-Young Lee

发表

d,l-Methadone causes leukemic cell apoptosis via an OPRM1-triggered increase in IP3R-mediated ER Ca2+ release and decrease in Ca2+ efflux, elevating [Ca2+]i

H. Byun, Jung-Kwon Lee, J. Rosales, 2021, Scientific Reports.

Centromeric chromatin integrity is compromised by loss of Cdk5rap2, a transcriptional activator of CENP-A.

Xidi Wang, Xu Gao, J. Rosales, 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Controversies over p25 in Alzheimer's disease.

J. Rosales, Ki-Young Lee, Kathy Nguyen, 2002, Journal of Alzheimer's disease : JAD.

ROS-Mediated Apoptosis in Cancer

J. Rosales, Ki-Young Lee, S. Navaneethakrishnan, 2022, Handbook of Oxidative Stress in Cancer: Mechanistic Aspects.

ROS-Mediated Apoptosis in Cancer

J. Rosales, Ki-Young Lee, S. Navaneethakrishnan, 2021, Handbook of Oxidative Stress in Cancer: Mechanistic Aspects.

Distinct transcriptional profiles of angioblasts derived from human embryonic stem cells.

Kyung-Ah Lee, W. Suh, Hyun Ok Kim, 2013, Experimental cell research.

Cdk5 in the centriolar appendages mediates cenexin1 localization and primary cilia formation

J. B. Rattner, J. Rosales, Ki-Young Lee, 2010, Cell cycle.

Cdk5 mediates vimentin ser56 phosphorylation during GTP‐induced secretion by neutrophils

Songbin Fu, J. Rosales, Ki-Young Lee, 2012, Journal of cellular physiology.

Elevated neuronal Cdc2-like kinase activity in the Alzheimer disease brain

A. Clark, R. Johnston, T. Fung, 1999, Neuroscience Research.

ODF1 Phosphorylation by Cdk5/p35 Enhances ODF1-OIP1 Interaction

K. Sarker, J. Rosales, Ki-Young Lee, 2007, Cellular Physiology and Biochemistry.

Interaction of Cyclin-dependent Kinase 5 (Cdk5) and Neuronal Cdk5 Activator in Bovine Brain (*)

Jerry H. Wang, D. Tang, J. Rosales, 1996, The Journal of Biological Chemistry.

Regulatory properties of neuronal cdc2-like kinase

I. Matsuura, Jerry H. Wang, Qi-Quan Huang, 1995, Molecular and Cellular Biochemistry.

Viewpoint: Crosstalks between neurofibrillary tangles and amyloid plaque formation

J. Rosales, Ki-Young Lee, K. Luan, 2013, Ageing Research Reviews.

Loss of Cdk5 in breast cancer cells promotes ROS-mediated cell death through dysregulation of the mitochondrial permeability transition pore

J. Rosales, Ki-Young Lee, S. Navaneethakrishnan, 2018, Oncogene.

Ebselen inhibits NO‐induced apoptosis of differentiated PC12 cells via inhibition of ASK1‐p38 MAPK‐p53 and JNK signaling and activation of p44/42 MAPK and Bcl‐2

I. Maruyama, T. Hashiguchi, K. Yamaji, 2003, Journal of neurochemistry.

ROS-Mediated Cancer Cell Killing through Dietary Phytochemicals

J. Rosales, Ki-Young Lee, S. Navaneethakrishnan, 2019, Oxidative medicine and cellular longevity.

HAP1 loss confers l-asparaginase resistance in ALL by downregulating the calpain-1-Bid-caspase-3/12 pathway.

Songbin Fu, H. Byun, Jung Kwon Lee, 2019, Blood.

Effect of iron on cholesterol 7α-hydroxylase expression in alcohol-induced hepatic steatosis in mice[S]

Y. Liu, Xu Gao, Ki-Young Lee, 2017, Journal of Lipid Research.

Cdk5/p25nck5a interaction with synaptic proteins in bovine brain

R. Johnston, J. Rosales, Ki-Young Lee, 2000, Journal of cellular biochemistry.

Cdk5/p35 expression in the mouse ovary.

Y. Fukui, N. Lee, Y. Jeong, 2004, Molecules and cells.

Identification of novel subregions of LOH in gastric cancer and analysis of the HIC1 and TOB1 tumor suppressor genes in these subregions

J. Bai, Songbin Fu, Yingwei Xue, 2011, Molecules and cells.

Neurofilaments are part of the high molecular weight complex containing neuronal cdc2-like kinase (nclk)

R. Johnston, Ki-Young Lee, 1997, Brain Research.

Cyclin E in breast tumors is cleaved into its low molecular weight forms by calpain

A. Magliocco, J. Rosales, Ki-Young Lee, 2003, Oncogene.

Tyrosine hydroxylase expression and Cdk5 kinase activity in ataxic cerebellum

Kevin J. Cheung, Y. Jeong, J. Rosales, 2008, Molecular and Cellular Biochemistry.

Reduced expression and novel splice variants of ING4 in human gastric adenocarcinoma

J. Bai, Songbin Fu, J. Geng, 2009, The Journal of pathology.

L6 myoblast differentiation is modulated by Cdk5 via the PI3K–AKT–p70S6K signaling pathway

K. Sarker, Ki-Young Lee, 2004, Oncogene.

Neutrophil TLR4 and PKR are targets of breast cancer cell glycosaminoglycans and effectors of glycosaminoglycan-induced APRIL secretion

Kelvin K.C. Chan, J. Rosales, Ki-Young Lee, 2018, Oncogenesis.

Outer Dense Fibers Serve as a Functional Target for Cdk5·p35 in the Developing Sperm Tail*

R. Oko, Y. Jeong, K. Sarker, 2004, Journal of Biological Chemistry.

Cdk5 Loss Alters Mitochondrial Cristae Organization

J. Rosales, Ki-Young Lee, S. Navaneetha krishnan, 2021 .

CDK5RAP2 loss-of-function causes premature cell senescence via the GSK3β/β-catenin-WIP1 pathway

Xidi Wang, Xu Gao, J. Rosales, 2021, Cell Death & Disease.

Loss of Cdk5rap2 triggers cellular senescence via β-catenin-mediated downregulation of WIP1

Xidi Wang, Xu Gao, J. Rosales, 2020, bioRxiv.

mPTP opening caused by Cdk5 loss is due to increased mitochondrial Ca2+ uptake

J. Rosales, Ki-Young Lee, S. Navaneethakrishnan, 2020, Oncogene.

Cdk5 regulates IP3R1-mediated Ca2+ dynamics and Ca2+-mediated cell proliferation

J. Rosales, Ki-Young Lee, Jungkwon Lee, 2022, Cellular and Molecular Life Sciences.

Saranya NavaneethaKrishnan1 · Vincent Law1 · Jungkwon Lee1 · Jesusa L. Rosales1 · Ki‐Young Lee1

J. Rosales, Ki-Young Lee, Jungkwon Lee, 2022 .

Cdk7 Functions as a Cdk5 Activating Kinase in Brain

Bingye Han, J. Rosales, Ki-Young Lee, 2003, Cellular Physiology and Biochemistry.

Design and biological evaluation of novel tubulin inhibitors as antimitotic agents using a pharmacophore binding model with tubulin.

Ki Young Lee, Cheol Kyu Han, Jeong Hyeok Yoon, 2006, Journal of medicinal chemistry.

Novel Functional MAR Elements of Double Minute Chromosomes in Human Ovarian Cells Capable of Enhancing Gene Expression

J. Bai, Songbin Fu, Zheng Liu, 2012, PloS one.

An Isoform of the Neuronal Cyclin-dependent Kinase 5 (Cdk5) Activator (*)

K. Tomizawa, M. Matsushita, H. Matsui, 1995, The Journal of Biological Chemistry.

Extraneuronal roles of cyclin‐dependent kinase 5

J. Rosales, Ki-Young Lee, 2006, BioEssays : news and reviews in molecular, cellular and developmental biology.

De novo-generated small palindromes are characteristic of amplicon boundary junction of double minutes

Jing Zhu, J. Bai, Ming-Rong Wang, 2013, International journal of cancer.

Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells

Jing Zhu, J. Bai, Chao Yuan, 2013, International journal of cancer.

ASK1–p38 MAPK/JNK signaling cascade mediates anandamide‐induced PC12 cell death

M. Yamakuchi, M. Kracht, I. Maruyama, 2003, Journal of neurochemistry.

Integration of a bacterial gene sequence into a chronic eosinophilic leukemia patient’s genome as part of a fusion gene linker

J. Rosales, Ki-Young Lee, S. Sidhoo, 2017, Biomarker Research.

Down‐regulation of ING4 is associated with initiation and progression of lung cancer

J. Bai, Songbin Fu, Lin-you Zhang, 2010, Histopathology.

Novel inhibitors targeted to methionine aminopeptidase 2 (MetAP2) strongly inhibit the growth of cancers in xenografted nude model

E. Chun, Yoon-Keun Kim, C. Han, 2005, International journal of cancer.

Neuronal Cdc2-like Kinase (Nclk) Binds and Phosphorylates the Retinoblastoma Protein*

R. Johnston, Jerry H. Wang, C. Helbing, 1997, The Journal of Biological Chemistry.

Enhancement of Peripheral Nerve Regrowth by the Purine Nucleoside Analog and Cell Cycle Inhibitor, Roscovitine

M. Jeong, V. Law, D. Zochodne, 2016, Front. Cell. Neurosci..

Ribosomal L22-like1 (RPL22L1) Promotes Ovarian Cancer Metastasis by Inducing Epithelial-to-Mesenchymal Transition

J. Bai, Songbin Fu, Jia Wei, 2015, PloS one.

Level of cdk5 expression predicts the survival of relapsed multiple myeloma patients

J. Rosales, Ki-Young Lee, Zachary Levacque, 2012, Cell cycle.

Requirement for ER-mitochondria Ca2+ transfer, ROS production and mPTP formation in L-asparaginase-induced apoptosis of acute lymphoblastic leukemia cells

Jung Kwon Lee, J. Rosales, Ki-Young Lee, 2023, Frontiers in Cell and Developmental Biology.

Novel role for non-homologous end joining in the formation of double minutes in methotrexate-resistant colon cancer cells

Jing Zhu, J. Bai, F. Chen, 2014, Journal of Medical Genetics.

Reconstitution of Neuronal Cdc2-like Kinase from Bacteria-expressed Cdk5 and an Active Fragment of the Brain-specific Activator

Jerry H. Wang, J. Lew, Ki-Young Lee, 1995, The Journal of Biological Chemistry.

Cdk5: A Mediator of Mptp Opening

J. Rosales, Ki-Young Lee, S. Navaneethakrishnan, 2020 .

Novel alternatively spliced variant form of human CDK5RAP2

Songbin Fu, J. Rosales, Ki-Young Lee, 2011, Cell cycle.

Clues for c-Yes involvement in the cell cycle and cytokinesis

Songbin Fu, J. Rosales, Ki-Young Lee, 2011, Cell Cycle.

GTP-dependent Secretion from Neutrophils Is Regulated by Cdk5*

J. Ernst, J. Hallows, J. Rosales, 2004, Journal of Biological Chemistry.

Inhibition of Thrombin-Induced Vascular Endothelial Growth Factor Production in Human Neuroblastoma (NB-1) Cells by Argatroban

M. Yamakuchi, I. Maruyama, T. Hashiguchi, 2005, Pathophysiology of Haemostasis and Thrombosis.

Integration of a bacterial gene sequence into a chronic eosinophilic leukemia patient’s genome as part of a fusion gene linker

J. Rosales, Ki-Young Lee, S. Sidhoo, 2017, Biomarker Research.

Thrombin Enhances NGF-Mediated Neurite Extension via Increased and Sustained Activation of p44/42 MAPK and p38 MAPK

Songbin Fu, K. Sarker, J. Rosales, 2014, PloS one.

Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion

J. Bai, F. Chen, Songbin Fu, 2009, British Journal of Cancer.

Neuronal Cdc2-like kinases: neuron-specific forms of Cdk5.

J. H. Wang, Jerry H. Wang, K. Y. Lee, 1997, The international journal of biochemistry & cell biology.