Ye Ding

发表

Direct Activation of Bax Protein for Cancer Therapy

Na Ye, Zhiqing Liu, Haiying Chen, 2016, Medicinal research reviews.

Modulation of Bax and mTOR for Cancer Therapeutics.

W. Curran, A. Magis, G. Sica, 2017, Cancer research.

Therapeutic Potential of Oridonin and Its Analogs: From Anticancer and Antiinflammation to Neuroprotection

Q. Shen, E. Wold, Jia Zhou, 2018, Molecules.

Oridonin inhibits hepatic stellate cell proliferation and fibrogenesis.

Xiaofu Wang, G. Radhakrishnan, R. Radhakrishnan, 2014, The Journal of surgical research.

Efficacy of Novel Aminooxyacetic Acid Prodrugs in Colon Cancer Models: Towards Clinical Translation of the Cystathionine β-Synthase Inhibition Concept

C. Szabó, Haiying Chen, Jia Zhou, 2021, Biomolecules.

Tu1975 H2S Inhibition of Cystathionine-β-Synthase (CBS) Using Novel Prodrug Decreases Colorectal Cancer Xenograft Growth With Less Toxicity Than Aminooxyacetic Acid (AOAA)

C. Szabó, Amy A. Mrazek, Jia Zhou, 2015 .

Targeting Krüppel-like factor 5 (KLF5) for cancer therapy.

Haijun Chen, Haiying Chen, Jia Zhou, 2015, Current topics in medicinal chemistry.

Antifibrosis Effect of Novel Oridonin Analog CYD0618 Via Suppression of the NF-κB Pathway.

Xiaofu Wang, R. Radhakrishnan, Haiying Chen, 2018, The Journal of surgical research.

BH4 domain of Bcl-2 as a novel target for cancer therapy.

Na Ye, Zhiqing Liu, Haiying Chen, 2016, Drug discovery today.

Regio- and Stereospecific Synthesis of Oridonin D-Ring Aziridinated Analogues for the Treatment of Triple-Negative Breast Cancer via Mediated Irreversible Covalent Warheads.

Na Ye, Deng-feng Li, Q. Shen, 2018, Journal of medicinal chemistry.

Enhanced anti-fibrogenic effects of novel oridonin derivative CYD0692 in hepatic stellate cells

Xiaofu Wang, G. Radhakrishnan, R. Radhakrishnan, 2015, Molecular and Cellular Biochemistry.

Anti-fibrosis Effect of Novel Oridonin Analog CYD0618 via Suppression of the NF- κΒ Pathway

Xiaofu Wang, R. Radhakrishnan, Haiying Chen, 2018 .

Targeting the NRF-2/RHOA/ROCK signaling pathway with a novel aziridonin, YD0514, to suppress breast cancer progression and lung metastasis.

Lin Fang, Jia Zhou, Qianjun Zhou, 2018, Cancer letters.

ent-Kaurane-based regio- and stereoselective inverse electron demand hetero-Diels-Alder reactions: synthesis of dihydropyran-fused diterpenoids.

Na Ye, Lili Wang, Q. Shen, 2014, Organic & biomolecular chemistry.

Suppression of Cocaine-Evoked Hyperactivity by Self-Adjuvanting and Multivalent Peptide Nanofiber Vaccines.

J. Rudra, Rajagopal Appavu, Haiying Chen, 2016, ACS chemical neuroscience.

Discovery and development of natural product oridonin-inspired anticancer agents.

Jia Zhou, Qiang Shen, Ye Ding, 2016, European journal of medicinal chemistry.

Small Molecule Inhibitors Targeting Activator Protein 1 (AP-1)

Na Ye, Q. Shen, Jia Zhou, 2014, Journal of medicinal chemistry.

Structure-activity relationship studies on Bax activator SMBA1 for the treatment of ER-positive and triple-negative breast cancer.

Hong Wang, Q. Shen, Haiying Chen, 2019, European journal of medicinal chemistry.

Discovery and Development of Natural Product Oridonin‐Inspired Anticancer Agents

Jia Zhou, Qiang Shen, Ye Ding, 2016 .

Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug Approach

T. Billiar, A. Papapetropoulos, K. Yanagi, 2016, Molecular Medicine.

Targeting 3-phosphoinositide-dependent protein kinase 1 associated with drug-resistant renal cell carcinoma using new oridonin analogs

D. He, J. Hsieh, R. Pong, 2017, Cell Death & Disease.

YD277 Suppresses Triple-Negative Breast Cancer Partially Through Activating the Endoplasmic Reticulum Stress Pathway

Rong Liu, Ceshi Chen, Haiying Chen, 2017, Theranostics.

Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug Approach

A. Papapetropoulos, K. Yanagi, C. Coletta, 2016, Molecular medicine.

A new oridonin analog suppresses triple-negative breast cancer cells and tumor growth via the induction of death receptor 5.

Zhongmei Zhou, Ceshi Chen, Haiying Chen, 2016, Cancer letters.

Enhanced effects of novel oridonin analog CYD0682 for hepatic fibrosis.

G. Radhakrishnan, R. Radhakrishnan, Jia Zhou, 2015, The Journal of surgical research.

Targeting XBP1-mediated β-catenin expression associated with bladder cancer with newly synthetic Oridonin analogues

A. Sagalowsky, D. He, J. Hsieh, 2016, Oncotarget.

Discovery of potent anticancer agent HJC0416, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3).

Na Ye, Lili Wang, Q. Shen, 2014, European journal of medicinal chemistry.

Enhanced anti-fibrogenic effects of novel oridonin derivative CYD0692 in hepatic stellate cells

G. Radhakrishnan, R. Radhakrishnan, Jia Zhou, 2015, Molecular and Cellular Biochemistry.

Design, synthesis, and characterization of novel apigenin analogues that suppress pancreatic stellate cell proliferation in vitro and associated pancreatic fibrosis in vivo.

Jia Zhou, Ye Ding, Amy A. Mrazek, 2014, Bioorganic & medicinal chemistry.

CYD0281, a Bcl-2 BH4 domain antagonist, inhibits tumor angiogenesis and breast cancer tumor growth

Jing Chen, Jia Zhou, Lingyun Zheng, 2023, BMC Cancer.

Direct Activation of Bax Protein for Cancer Therapy

Na Ye, Zhiqing Liu, Haiying Chen, 2016, Medicinal research reviews.

ent-Kaurane-based regio- and stereoselective inverse electron demand hetero-Diels-Alder reactions: synthesis of dihydropyran-fused diterpenoids.

Na Ye, Lili Wang, Q. Shen, 2014, Organic & biomolecular chemistry.