M. Kovalenko

发表

HttQ111/+ Huntington’s Disease Knock-in Mice Exhibit Brain Region-Specific Morphological Changes and Synaptic Dysfunction

L. Raymond, T. Gillis, M. MacDonald, 2018, Journal of Huntington's disease.

Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice

S. Haggarty, S. Erdin, M. Talkowski, 2020, eLife.

Somatic CAG expansion in Huntington’s disease is dependent on the MLH3 endonuclease domain, which can be excluded via MLH3 splice redirection to suppress expansion

P. Cohen, V. Wheeler, R. M. Pinto, 2020, bioRxiv.

Huntingtin lowering reduces somatic instability at CAG-expanded loci

D. Marchionini, S. Tabrizi, S. Zeitlin, 2020, bioRxiv.

Msh 2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington ' s disease knockin mice

T. Gillis, R. Kucherlapati, M. Kucherlapati, 2018 .

High resolution time‐course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington's disease CAG knock‐in mice across multiple genetic backgrounds

John C. Earls, L. Hood, D. Geman, 2017, Human molecular genetics.

Chromosome substitution strain assessment of a Huntington’s disease modifier locus

T. Gillis, J. Mysore, M. MacDonald, 2015, Mammalian Genome.

Msh2 Acts in Medium-Spiny Striatal Neurons as an Enhancer of CAG Instability and Mutant Huntingtin Phenotypes in Huntington’s Disease Knock-In Mice

T. Gillis, R. Kucherlapati, M. Kucherlapati, 2012, PloS one.

Identification of genetic modifiers of somatic CAG instability in Huntington's Disease by in vivo CRISPR - Cas9 genome editing: PS238.

V. Wheeler, M. Pinto, F. Zhang, 2017, Porto biomedical journal.

Defective linear and circular RNAs biogenesis in Huntington’s disease: CAG repeat expansion hijacks neuronal splicing

C. Dieterich, E. Dassi, S. Piazza, 2021 .

Somatic CAG expansion in Huntington's disease is dependent on the MLH3 endonuclease domain, which can be excluded via splice redirection

P. Cohen, V. Wheeler, M. Kovalenko, 2021, Nucleic acids research.

Chromosome substitution strain assessment of a Huntington’s disease modifier locus

T. Gillis, J. Mysore, M. MacDonald, 2015, Mammalian Genome.

A Broad Phenotypic Screen Identifies Novel Phenotypes Driven by a Single Mutant Allele in Huntington’s Disease CAG Knock-In Mice

Edith T. Lopez, H. Fuchs, T. Gillis, 2013, PloS one.

Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington’s disease knock-in mice is blocked by Mlh1 knock-out

T. Gillis, J. Mysore, M. MacDonald, 2020, Human molecular genetics.

Selecting features from multiple feature sets for SVM committee-based screening of human larynx

Antanas Verikas, Adas Gelzinis, Marija Bacauskiene, 2010, Expert Syst. Appl..

High resolution time‐course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington's disease CAG knock‐in mice across multiple genetic backgrounds

John C. Earls, L. Hood, D. Geman, 2017, Human molecular genetics.

CAG repeat expansion in the Huntington’s disease gene shapes linear and circular RNAs biogenesis

V. Wheeler, E. Kerschbamer, J. Döring, 2023, PLoS genetics.