Masaya Orita

发表

Large-Scale Computing for Protein-Protein Binding Free Energy Calculation

Yoichi Muraoka, Sayaka Akioka, Tamotsu Noguchi, 2008, PDPTA.

Agreement of drug discovery data with Benford's law

Yosuke Hagiwara, Kazuki Ohno, Masaya Orita, 2013, Expert opinion on drug discovery.

Accelerating quantum chemistry calculations with graphical processing units - toward in high-density (HD) silico drug discovery.

Toshio Endo, Masakazu Sekijima, Yutaka Akiyama, 2013, Current computer-aided drug design.

Use of Benford's law in drug discovery data.

Kazuki Ohno, Masaya Orita, Ayako Moritomo, 2010, Drug discovery today.

Are There Differences between Launched Drugs, Clinical Candidates, and Commercially Available Compounds?

Yuichi Nagahara, Kazuki Ohno, Masaya Orita, 2010, J. Chem. Inf. Model..

Two 'Golden Ratio' indices in fragment-based drug discovery.

Kazuki Ohno, Masaya Orita, Tatsuya Niimi, 2009, Drug discovery today.

Rating high‐throughput screening results via h‐index

Kazuki Ohno, Masaya Orita, Yohsuke Hagiwara, 2014 .

Small-World Phenomena in Chemical Library Networks: Application to Fragment-Based Drug Discovery

Naoki Tanaka, Kazuki Ohno, Masaya Orita, 2009, J. Chem. Inf. Model..

Selection of In Silico Drug Screening Results by Using Universal Active Probes (UAPs)

Haruki Nakamura, Yoshifumi Fukunishi, Kazuki Ohno, 2010, J. Chem. Inf. Model..

In Silico Fragment Screening by Replica Generation (FSRG) Method for Fragment-Based Drug Design

Haruki Nakamura, Yoshifumi Fukunishi, Kazuki Ohno, 2009, J. Chem. Inf. Model..

Discovery of highly potent and selective biphenylacylsulfonamide-based beta3-adrenergic receptor agonists and molecular modeling based on the solved X-ray structure of the beta2-adrenergic receptor: part 6.

Nobuhiro Yamamoto, Minoru Sakurai, Masaya Orita, 2009, Bioorganic & medicinal chemistry letters.

Quantitative analysis of aggregation-solubility relationship by in-silico solubility prediction

Haruki Nakamura, Yoshifumi Fukunishi, Masaya Orita, 2010 .

Corrigendum to “Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure–activity relationships of pyrimidine-5-carboxamide derivatives” [Bioorg. Med. Chem. 13 (2005) 4936–4951]

Masaya Orita, Atsushi Ichikawa, Ryo Naito, 2005 .

Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives.

Masaya Orita, Atsushi Ichikawa, Ryo Naito, 2005, Bioorganic & medicinal chemistry.

Lead generation and examples opinion regarding how to follow up hits.

Masaya Orita, Tatsuya Niimi, K. Ohno, 2011, Methods in enzymology.

Advances in fragment-based drug discovery platforms

Masaya Orita, Yasushi Amano, Tatsuya Niimi, 2009, Expert opinion on drug discovery.

Formation of a catalytically active dimer by tRNAVal -driven short ribozymes

Masaya Orita, Kazunari Taira, Tomoko Kuwabara, 1998, Bio/Technology.

A novel target recognition revealed by calmodulin in complex with Ca2+-calmodulin-dependent kinase kinase

Masaya Orita, Masanori Osawa, Mitsuhiko Ikura, 1999, Nature Structural Biology.