Y. Fujioka

发表

Synthesis and evaluation of a monoreactive DOTA derivative for indium‐111‐based residualizing label to estimate protein pharmacokinetics

J. Konishi, H. Saji, K. Ogawa, 2002, The Journal of pharmacy and pharmacology.

Evaluation of cytochrome P450-mediated drug–drug interactions based on the strategies recommended by regulatory authorities

Y. Kosugi, H. Hirabayashi, Tomoko Igari, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

Rationalization and prediction of in vivo metabolite exposures: the role of metabolite kinetics, clearance predictions and in vitro parameters

N. Isoherranen, Y. Fujioka, J. Lutz, 2010, Expert opinion on drug metabolism & toxicology.

The integrity of the disulfide bond in a cyclic somatostatin analog during 99mTc complexation reactions.

H. Saji, N. Fujii, K. Ogawa, 1999, Nuclear Medicine and Biology.

Control of radioactivity pharmacokinetics of 99mTc-HYNIC-labeled polypeptides derivatized with ternary ligand complexes.

T. Saga, J. Konishi, H. Saji, 2002, Bioconjugate chemistry.

(99m)Tc-HYNIC-derivatized ternary ligand complexes for (99m)Tc-labeled polypeptides with low in vivo protein binding.

T. Saga, J. Konishi, H. Saji, 2001, Nuclear medicine and biology.

Plasma protein binding of (99m)Tc-labeled hydrazino nicotinamide derivatized polypeptides and peptides.

T. Saga, J. Konishi, H. Saji, 2001, Nuclear medicine and biology.

Chemical design of radiolabeled antibody fragments for low renal radioactivity levels.

H. Sakahara, J. Konishi, H. Saji, 1999, Cancer research.

In vitro system to estimate renal brush border enzyme-mediated cleavage of Peptide linkages for designing radiolabeled antibody fragments of low renal radioactivity levels.

H. Saji, K. Ogawa, K. Endo, 2005, Bioconjugate chemistry.

Intracellular metabolic fate of radioactivity after injection of technetium-99m-labeled hydrazino nicotinamide derivatized proteins.

H. Saji, K. Ogawa, M. Ono, 1999, Bioconjugate chemistry.

Amine-free melanin-concentrating hormone receptor 1 antagonists: Novel 1-(1H-benzimidazol-6-yl)pyridin-2(1H)-one derivatives and design to avoid CYP3A4 time-dependent inhibition.

Masaharu Nakayama, S. Okuda, Masashi Takahashi, 2016, Bioorganic & medicinal chemistry.

Effect of molecular charges on renal uptake of 111In-DTPA-conjugated peptides.

H. Saji, K. Ogawa, Y. Kiso, 2001, Nuclear medicine and biology.

Renal metabolism of 111In-DTPA-D-Phe1-octreotide in vivo.

H. Saji, Y. Kiso, M. Ono, 1998, Bioconjugate chemistry.

Renal metabolism of 3'-iodohippuryl N(epsilon)-maleoyl-L-lysine (HML)-conjugated Fab fragments.

T. Saga, J. Konishi, H. Saji, 2001, Bioconjugate chemistry.

Design, synthesis, and biological evaluation of a novel series of peripheral-selective noradrenaline reuptake inhibitors - Part 3.

T. Tsukamoto, H. Ueno, Ikuo Fujimori, 2016, Bioorganic & medicinal chemistry.

Discovery, synthesis, and structure-activity relations of 3,4-dihydro-1H-spiro(naphthalene-2,2'-piperidin)-1-ones as potassium-competitive acid blockers.

Terufumi Takagi, T. Imaeda, F. Itoh, 2017, Bioorganic & medicinal chemistry.

Clarification of P-glycoprotein inhibition-related drug–drug interaction risks based on a literature search of the clinical information

Teruaki Okuda, Y. Fujioka, Yukari Umeyama, 2014, Xenobiotica; the fate of foreign compounds in biological systems.

Establishment and validation of a rabbit model for in vivo pharmacodynamic screening of tachykinin NK2 antagonists.

Takahiro Tanaka, M. Yamaguchi, H. Kamiguchi, 2012, Journal of pharmacological sciences.

Identification of a novel fluoropyrrole derivative as a potassium-competitive acid blocker with long duration of action.

Teruki Hamada, T. Imaeda, F. Itoh, 2017, Bioorganic & medicinal chemistry.

Exploration of pyrrole derivatives to find an effective potassium-competitive acid blocker with moderately long-lasting suppression of gastric acid secretion.

Ikuo Fujimori, F. Itoh, Y. Fujioka, 2017, Bioorganic & medicinal chemistry.

Evaluation of Acid Tolerance of Drugs Using Rats and Dogs Controlled for Gastric Acid Secretion.

Noriyasu Sano, Atsutoshi Furuta, N. Amano, 2015, Journal of pharmaceutical sciences.

Direct Drug Delivery of Low-Permeable Compounds to the Central Nervous System Via Intranasal Administration in Rats and Monkeys

S. Iwasaki, Teruki Hamada, Noriyasu Sano, 2019, Pharmaceutical Research.

A novel immunoscintigraphy technique using metabolizable linker with angiotensin II treatment

H. Sakahara, T. Saga, J. Konishi, 1999, British Journal of Cancer.

Significance of (111)In-DTPA chelate in renal radioactivity levels of (111)In-DTPA-conjugated peptides.

H. Saji, K. Ogawa, Y. Kiso, 2001, Nuclear medicine and biology.

Are Circulating Metabolites Important in Drug–Drug Interactions?: Quantitative Analysis of Risk Prediction and Inhibitory Potency

R H Levy, N. Isoherranen, H. Hachad, 2011, Clinical pharmacology and therapeutics.

ERRATUM: Are Circulating Metabolites Important in Drug–Drug Interactions?: Quantitative Analysis of Risk Prediction and Inhibitory Potency

H. Hachad, Y. Fujioka, C. Yeung, 2011 .

Risk Assessment of Mechanism-Based Inactivation in Drug-Drug Interactions

N. Isoherranen, K. Kunze, Y. Fujioka, 2012, Drug Metabolism and Disposition.

Direct Drug Delivery of Low-Permeable Compounds to the Central Nervous System Via Intranasal Administration in Rats and Monkeys

S. Iwasaki, Teruki Hamada, Noriyasu Sano, 2019, Pharmaceutical Research.