Yu Chang

发表

Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation.

Yan Zhang, Yong Xu, Shan Li, 2019, ACS medicinal chemistry letters.

Discovery of JND003 as a New Selective Estrogen-Related Receptor α Agonist Alleviating Nonalcoholic Fatty Liver Disease and Insulin Resistance

N. Wang, Donghai Wu, Andrew E. Libby, 2022, ACS bio & med chem Au.

Studies of pharmacokinetics in beagle dogs and drug-drug interaction potential of a novel selective ZAK inhibitor 3h for hypertrophic cardiomyopathy treatment.

R. Dai, Yu Chang, Weifan Jiang, 2019, Journal of pharmaceutical and biomedical analysis.

Cell- and Tissue-Based Proteome Profiling and Dual Imaging of Apoptosis Markers with Probes Derived from Venetoclax and Idasanutlin

Yong Xu, P. Hao, Zhengqiu Li, 2018, Angewandte Chemie.

Proteome-wide Identification of Off-Targets of a Potent EGFRL858R/T790M Mutant Inhibitor.

P. Hao, Zhengqiu Li, Peng Lyu, 2022, ACS medicinal chemistry letters.

Enantioselective semisynthesis of novel cephalotaxine esters with potent antineoplastic activities against leukemia.

Ruxi Qi, Qingwen Zhang, Zhang Zhang, 2022, European journal of medicinal chemistry.

Identification and optimization of new dual inhibitors of B-Raf and epidermal growth factor receptor kinases for overcoming resistance against vemurafenib.

Xiaoyun Lu, Qingwen Zhang, Zheng-chao Tu, 2014, Journal of medicinal chemistry.

Practical synthesis of potential endothelin receptor antagonists of 1,4-benzodiazepine-2,5-dione derivatives bearing substituents at the C3-, N1- and N4-positions.

Jim-Min Fang, Hui‐Ming Yu, Ming-Fu Cheng, 2006, Organic & biomolecular chemistry.

Crenolanib‐Derived Probes Suitable for Cell‐ and Tissue‐Based Protein Profiling and Single‐Cell Imaging

Xingfeng Yin, Zhengqiu Li, Ke Ding, 2019, Chembiochem : a European journal of chemical biology.

Minimalist linkers suitable for irreversible inhibitors in simultaneous proteome profiling, live-cell imaging and drug screening.

P. Hao, Zhengqiu Li, Ke Ding, 2019, Chemical communications.

Cell- and Tissue-Based Proteome Profiling and Dual Imaging of Apoptosis Markers with Probes Derived from Venetoclax and Idasanutlin.

Yong Xu, P. Hao, Zhengqiu Li, 2018, Angewandte Chemie.

A new cycloartane-type triterpenoid from the roots of Dianella ensifolia (L.) DC

S. Lee, Yu Chang, Jian-bo Sun, 2017, Natural product research.

Pyrido[2, 3-d]pyrimidin-7(8H)-ones as new selective orally bioavailable Threonine Tyrosine Kinase (TTK) inhibitors.

Yong Xu, Xiaoyun Lu, Zheng-chao Tu, 2020, European journal of medicinal chemistry.

Tyrosine Kinase 2 (TYK2) Allosteric Inhibitors To Treat Autoimmune Diseases.

Shili Xu, Ke Ding, Yu Chang, 2019, Journal of medicinal chemistry.

Structure Based Design of N-(3-((1H-Pyrazolo[3,4-b]pyridin-5-yl)ethynyl)benzenesulfonamides as Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors.

Yan Zhang, Yong Xu, Chih-Yang Huang, 2017, Journal of medicinal chemistry.

Determination of a novel B-Raf(V600E) and EGFR dual inhibitor in rat plasma by HPLC-MS/MS and its application in a pharmacokinetic study.

Jifeng Deng, Yu Chang, Hui-Min Cheng, 2016, Journal of pharmaceutical and biomedical analysis.

Minimalist linkers suitable for irreversible inhibitors in simultaneous proteome profiling, live-cell imaging and drug screening.

P. Hao, Zhengqiu Li, Ke Ding, 2019, Chemical communications.

Structure Based Design of N-(3-((1H-Pyrazolo[3,4-b]pyridin-5-yl)ethynyl)benzenesulfonamides as Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors.

Yan Zhang, Yong Xu, Chih-Yang Huang, 2017, Journal of medicinal chemistry.