H. Nara

发表

Pharmacological difference between degrader and inhibitor against oncogenic BCR-ABL kinase

M. Naito, Tomoya Sameshima, N. Cho, 2018, Scientific Reports.

Nucleosides and nucleotides. 135. DNA duplex and triplex formation and resistance to nucleolytic degradation of oligodeoxynucleotides containing syn-norspermidine at the 5-position of 2'-deoxyuridine.

A. Matsuda, A. Ono, H. Nara, 1995, Bioconjugate chemistry.

Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1″ binding site.

H. Oki, Kenjiro Sato, O. Uchikawa, 2014, Bioorganic & medicinal chemistry.

Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands.

M. Naito, Ryokichi Koyama, N. Cho, 2017, Journal of medicinal chemistry.

Twenty-six-week carcinogenicity study of sulfamethoxazole in CB6F1-Tg-rasH2 mice.

M. Torii, H. Nara, K. Hirano, 2001, The Journal of toxicological sciences.

Different Degradation Mechanisms of Inhibitor of Apoptosis Proteins (IAPs) by the Specific and Nongenetic IAP-Dependent Protein Eraser (SNIPER).

M. Naito, Tomoya Sameshima, N. Cho, 2019, Chemical & pharmaceutical bulletin.

Targeting the Allosteric Site of Oncoprotein BCR-ABL as an Alternative Strategy for Effective Target Protein Degradation.

M. Naito, Tomoya Sameshima, N. Cho, 2017, ACS medicinal chemistry letters.

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Amber L. Couzens, M. Tyers, A. Gingras, 2018, Nature Communications.

Development of protein degradation inducers of oncogenic BCR‐ABL protein by conjugation of ABL kinase inhibitors and IAP ligands

M. Naito, Tomoya Sameshima, N. Cho, 2017, Cancer science.

Discovery of novel, highly potent, and selective quinazoline-2-carboxamide-based matrix metalloproteinase (MMP)-13 inhibitors without a zinc binding group using a structure-based design approach.

H. Oki, Kenjiro Sato, O. Uchikawa, 2014, Journal of medicinal chemistry.

Design, synthesis, and biological activity of novel, potent, and highly selective fused pyrimidine-2-carboxamide-4-one-based matrix metalloproteinase (MMP)-13 zinc-binding inhibitors.

H. Oki, Kenjiro Sato, A. Kaieda, 2016, Bioorganic & medicinal chemistry.

Nucleosides and nucleotides. 126. Incorporation of a mutagenic nucleoside, 5-formyl-2′-deoxyuridine, into an oligodeoxyribonucleotide☆

A. Matsuda, E. Ohtsuka, A. Ono, 1993 .

Nucleosides and nucleotides. 131. Synthesis and properties of oligonucleotides containing 5-formyl-2'-deoxyuridine.

A. Matsuda, A. Ono, H. Nara, 1994, Chemical & pharmaceutical bulletin.

Derivatization of inhibitor of apoptosis protein (IAP) ligands yields improved inducers of estrogen receptor α degradation

M. Naito, Ryokichi Koyama, Tomoya Sameshima, 2018, The Journal of Biological Chemistry.

In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs)*

M. Naito, Ryokichi Koyama, Mika Teratani, 2017, The Journal of Biological Chemistry.

SNIPER(TACC3) induces cytoplasmic vacuolization and sensitizes cancer cells to Bortezomib

M. Naito, N. Cho, N. Shibata, 2017, Cancer science.

Steroid-induced concentric membrane whorls in dog liver

H. Watanabe, H. Nara, Y. Muraoka, 1981, Experientia.

Discovery of Novel, Highly Potent, and Selective Matrix Metalloproteinase (MMP)-13 Inhibitors with a 1,2,4-Triazol-3-yl Moiety as a Zinc Binding Group Using a Structure-Based Design Approach.

H. Oki, Kenjiro Sato, A. Kaieda, 2017, Journal of medicinal chemistry.

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Amber L. Couzens, M. Tyers, A. Gingras, 2020, Nature Communications.

EFFECTS OF ESTROGEN ON MOUSE LIVER SINUSOIDAL CELLS

T. Maruyama, M. Okada, M. Torii, 1995 .

Pharmacological difference between degrader and inhibitor against oncogenic BCR-ABL kinase

M. Naito, Tomoya Sameshima, N. Cho, 2018, Scientific Reports.

Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1″ binding site.

H. Oki, Kenjiro Sato, O. Uchikawa, 2014, Bioorganic & medicinal chemistry.