T. Magee

发表

Progress in discovery of small-molecule modulators of protein-protein interactions via fragment screening.

T. Magee, 2015, Bioorganic & medicinal chemistry letters.

Pharmacologic inhibition of ketohexokinase prevents fructose-induced metabolic dysfunction

M. Birnbaum, G. Sonnenberg, J. Pfefferkorn, 2021, Molecular metabolism.

A pyrolysis mass spectrometry study of the non-pigmented Prevotela species

R., I.., T. Magee, 2022 .

Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK).

J. Pandit, J. Culp, K. Parris, 2017, Journal of medicinal chemistry.

Discovery of Selective Small Molecule Inhibitors of Monoacylglycerol Acyltransferase 3.

C. C. Jorgensen, Hao Sun, M. Boehm, 2015, Journal of medicinal chemistry.

Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)

P. Loria, T. Rolph, D. Hepworth, 2015, Scientific Reports.

Optimization of a Dicarboxylic Series for in Vivo Inhibition of Citrate Transport by the Solute Carrier 13 (SLC13) Family.

T. Rolph, M. Hayward, D. Erion, 2016, Journal of medicinal chemistry.

Discovery of azetidinyl ketolides for the treatment of susceptible and multidrug resistant community-acquired respiratory tract infections.

Bryan M. Li, T. Dougherty, R. Obach, 2009, Journal of medicinal chemistry.

Process Development of a Novel Azetidinyl Ketolide Antibiotic

Glenn E Wilcox, Bryan M. Li, M. Flanagan, 2012 .

Finasteride, a 5alpha-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice.

M. Rogawski, S. Yamaguchi, T. Kokate, 1999, The Journal of pharmacology and experimental therapeutics.

Application of emerging biomarkers of acute kidney injury in development of kidney-sparing polypeptide-based antibiotics

J. Aubrecht, T. Magee, D. Ackley, 2014, Drug and chemical toxicology.

A straightforward route to functionalized intermediates containing the CD substructure of taxol.

W. Bornmann, S. Danishefsky, T. Magee, 1992 .

Synthesis of 12-membered macrocyclic templates and library analogs for PPI

Yingfu Li, F. Rong, M. Troutman, 2013 .

Cyclic homopentapeptides 1. Analogs of tuberactinomycins and capreomycin with activity against vancomycin-resistant enterococci and Pasteurella

S. Miller, J. Lyssikatos, M. Lemay, 1997 .

7.18 – Macrolide Antibiotics

T. Dougherty, T. Kaneko, T. Magee, 2007 .

Composition of American distilled tall oils

T. Magee, D. F. Zinkel, 1992 .

Novel antibacterial compounds addressing resistance: patent disclosures 2002 – 2005

T. Dougherty, T. Magee, 2005 .

Diterpene resin acids from the needle oleoresin of pinus strobus

T. Magee, D. F. Zinkel, 1987 .

Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.

V. Shanmugasundaram, M. Huband, E. Marr, 2013, Bioorganic & medicinal chemistry letters.

Driving Drug Discovery with Biophysical Information

G. Karam, V. Shanmugasundaram, A. Palmer, 2017 .

Developmental Regulation ofaSporulation-Specific Enzyme Activity inSaccharomyces cerevisiaet

M. Clancy, T. Magee, 1982 .

Major resin acids of Pinus nigra needles

T. Magee, D. F. Zinkel, Jocclyn Walter, 1985 .

Discovery of Dap-3 polymyxin analogues for the treatment of multidrug-resistant Gram-negative nosocomial infections.

Bryan M. Li, A. Stepan, J. Aubrecht, 2013, Journal of medicinal chemistry.

Cyclic homopentapeptides 3. Synthetic modifications to the capreomycins and tuberactinomycins: Compounds with activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci

J. Lyssikatos, D. Whipple, R. Chandrasekaran, 1997 .

Cyclic Homopentapeptides. Part 3. Synthetic Modifications to the Capreomycins and Tuberactinomycins: Compounds with Activity Against Methicillin-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococci.

J. Lyssikatos, D. Whipple, R. Chandrasekaran, 1997 .

Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose.

J. Pandit, K. Parris, David A. Price, 2020, Journal of medicinal chemistry.

A total synthesis of rac-patchouli alcohol

G. Stork, T. Magee, P. Fludzinski, 1995 .

Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism.

K. Fennell, J. Pandit, K. Parris, 2016, ACS chemical biology.

Design of a multi-purpose fragment screening library using molecular complexity and orthogonal diversity metrics

James E. J. Mills, Michael D. Miller, Li Xing, 2011, J. Comput. Aided Mol. Des..