J. Josephs

发表

International Perspectives on Environmental Nanotechnology Applications and Implications Conference

I. Linkov, B. Karn, D. LePoire, 2010 .

Synthesis of the Calophyllum coumarins. Part 2

C. Palmer, J. Josephs, 1995 .

High-Throughput Peptide Mapping with the Vanquish UHPLC System and the Q Exactive HF Mass Spectrometer

R. Swart, Martin Samonig, J. Josephs, 2015 .

Algorithm for thorough background subtraction of high-resolution LC/MS data: application to obtain clean product ion spectra from nonselective collision-induced dissociation experiments.

W. Humphreys, Haiying Zhang, J. Josephs, 2009, Analytical chemistry.

Hybrid Mass Analyzers in Drug Metabolism Applications

W. Humphreys, R. Ramanathan, J. Josephs, 2012 .

Metabolite Generation via Microbial Biotransformations with Actinomycetes: Rapid Screening for Active Strains and Biosynthesis of Important Human Metabolites of Two Development-Stage Compounds, 5-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non7-yl-methy

W. Humphreys, G. Skiles, J. Josephs, 2008, Drug Metabolism and Disposition.

A Case Study to Identify the Drug Conjugation Site of a Site-Specific Antibody-Drug-Conjugate Using Middle-Down Mass Spectrometry

S. Cianférani, A. Beck, R. Huguet, 2019, Journal of The American Society for Mass Spectrometry.

Quantitative estimation of circulating metabolites without synthetic standards by ultra-high-performance liquid chromatography/high resolution accurate mass spectrometry in combination with UV correction.

W. Humphreys, Yanou Yang, J. Josephs, 2011, Rapid communications in mass spectrometry : RCM.

Enabling Mass Spectrometric Analysis of Intact Proteins in Native Conditions on A Hybrid Quadrupole-Orbitrap Mass Spectrometer

A. Bailey, Eugen Damoc, J. Josephs, 2016 .

An automated high throughput liquid chromatography-mass spectrometry process to assess the metabolic stability of drug candidates.

James V Belcastro, K. Dickinson, C. Mcnaney, 2007, Assay and drug development technologies.

A semi-automated method for the integrated evaluation of half-life and metabolic soft spots of discovery compounds.

W. Humphreys, J. Josephs, M. Grubb, 2012, Bioanalysis.

The rotenoid core structure: Modifications to define the requirements of the toxophore.

L. Crombie, J. Weston, J. Josephs, 1992 .

Bioactivation of 2-(alkylthio)-1,3,4-thiadiazoles and 2-(alkylthio)-1,3-benzothiazoles.

W. Humphreys, Y. Shu, Yanou Yang, 2012, Chemical research in toxicology.

Synthesis of the calophyllum coumarins

C. Palmer, J. Josephs, 1994 .

Development, optimization and implementation of a centralized metabolic soft spot assay.

I. Zamora, Y. Shu, T. Zvyaga, 2017, Bioanalysis.

Rotenoid synthesis by Wadsworth–Emmons coupling and Mukaiyama cyclisation: application to 5-thiorotenoids

L. Crombie, J. Josephs, 1993 .

Discovery of Potent Protease-Activated Receptor 4 Antagonists with in vivo Antithrombotic Efficacy.

Shana L. Posy, D. Seiffert, Yanou Yang, 2019, Journal of medicinal chemistry.

Detection and characterization of fumonisin mycotoxins by liquid chromatography/electrospray ionization using ion trap and triple quadrupole mass spectrometry.

J. Josephs, 1996, Rapid communications in mass spectrometry : RCM.

Synthetic modulation of the peripheral 2-, 3-, 9- and 12-oxygenation pattern of rotenoids

L. Crombie, J. Josephs, 1993 .

Determination of buprenorphine in human plasma by gas chromatography-positive ion chemical ionization mass spectrometry and liquid chromatography-tandem mass spectrometry.

D J Crouch, R L Foltz, W K Bickel, 1997, Journal of analytical toxicology.

Changing Role of FTMS in Drug Metabolism

P. Shipkova, M. Sanders, J. Josephs, 2008 .

Charge variant native mass spectrometry benefits mass precision and dynamic range of monoclonal antibody intact mass analysis

Jennifer N. Sutton, P. Gazis, W. Sandoval, 2018, mAbs.

On the inter-instrument and the inter-laboratory transferability of a tandem mass spectral reference library. 3. Focus on ion trap and upfront CID.

Thomas Letzel, Herbert Oberacher, Sylvia Grosse, 2012, Journal of mass spectrometry : JMS.

Sensitive, High-Throughput, and Robust Trapping-Micro-LC-MS Strategy for the Quantification of Biomarkers and Antibody Biotherapeutics.

J. Canty, Shaolian Zhou, R. Young, 2018, Analytical chemistry.

Strategy to improve the quantitative LC-MS analysis of molecular ions resistant to gas-phase collision induced dissociation: application to disulfide-rich cyclic peptides.

Timothy Olah, Dieter M Drexler, Jonathan L Josephs, 2014, Analytical chemistry.

HRMS: current usage, future directions and the promise of integration with unified data streams suited to post-acquisition mining.

J. Josephs, 2012, Bioanalysis.

Characterization of over-the-counter cough/cold medications by liquid chromatography/electrospray mass spectrometry

J. Josephs, Jonathan L. Josephs, 1995 .

Novel MS solutions inspired by MIST.

Ragu Ramanathan, Mohammed Jemal, Mark Arnold, 2010, Bioanalysis.

Creation and comparison of MS/MS spectral libraries using quadrupole ion trap and triple-quadrupole mass spectrometers.

Jonathan L Josephs, M. Sanders, Mark Sanders, 2004, Rapid communications in mass spectrometry : RCM.

A Case Study to Identify the Drug Conjugation Site of a Site-Specific Antibody-Drug-Conjugate Using Middle-Down Mass Spectrometry

S. Cianférani, A. Beck, R. Huguet, 2019, Journal of The American Society for Mass Spectrometry.