K. Pyakurel

发表

DNA-dependent protein kinase inhibition blocks asthma in mice and modulates human endothelial and CD4⁺ T-cell function without causing severe combined immunodeficiency.

A. Boulares, Ji-hang Ju, A. Naura, 2015, The Journal of allergy and clinical immunology.

Fuelling the mechanisms of asthma: Increased fatty acid oxidation in inflammatory immune cells may represent a novel therapeutic target

A. Boulares, L. Del Valle, S. Okpechi, 2017, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Allergic Disease Fueling the Mechanisms of Asthma : Increased Fatty Acid Oxidation in Inflammatory Immune Cells May Represent a Novel Therapeutic Target Running title : Fatty Acid Oxidation Inhibition Blocks Asthma-Like Traits in Mice

A. Boulares, S. Okpechi, D. Wyczechowska, 2017 .

Sulfated non-anticoagulant heparin blocks Th2-induced asthma by modulating the IL-4/signal transducer and activator of transcription 6/Janus kinase 1 pathway

S. Mousa, A. Boulares, K. Pyakurel, 2018, Journal of Translational Medicine.

Minocycline Blocks Asthma-associated Inflammation in Part by Interfering with the T Cell Receptor-Nuclear Factor κB-GATA-3-IL-4 Axis without a Prominent Effect on Poly(ADP-ribose) Polymerase*

J. Jordán, A. Boulares, A. Catling, 2012, The Journal of Biological Chemistry.

PARP is activated in human asthma and its inhibition by olaparib blocks house dust mite-induced disease in mice

A. Boulares, A. Naura, Hogyoung Kim, 2015, Clinical science.

DNA-PK inhibition blocks asthma in mice and modulates human endothelial and CD4 + T cell function without causing SCID

A. Boulares, Ji-hang Ju, A. Naura, 2015 .

PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4+ T cell function

A. Boulares, A. Naura, A. Ramsay, 2015, Journal of Translational Medicine.

Potential of Inducible Nitric Oxide Synthase as a Therapeutic Target for Allergen-Induced Airway Hyperresponsiveness: A Critical Connection to Nitric Oxide Levels and PARP Activity

A. Boulares, K. Pyakurel, M. Lammi, 2016, Mediators of inflammation.

Acute effect of inhaled iloprost on exercise dynamic hyperinflation in COPD patients: A randomized crossover study.

John B. Zamjahn, A. Boulares, J. Shellito, 2021, Respiratory medicine.

Microparticles in systemic sclerosis: Potential pro‐inflammatory mediators and pulmonary hypertension biomarkers

A. Boulares, S. Okpechi, L. Saketkoo, 2019, Respirology.

Sulfated non-anticoagulant heparin blocks Th2-induced asthma by modulating the IL-4/signal transducer and activator of transcription 6/Janus kinase 1 pathway

S. Mousa, A. Boulares, K. Pyakurel, 2018, Journal of Translational Medicine.

PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4+ T cell function

A. Boulares, A. Naura, A. Ramsay, 2015, Journal of Translational Medicine.

Treatment with intranasal iloprost reduces disease manifestations in a murine model of previously established COPD.

A. Boulares, J. Shellito, A. Naura, 2016, American journal of physiology. Lung cellular and molecular physiology.

MINOCYCLINE BLOCKS ASTHMA-ASSOCIATED INFLAMMATION IN PART BY INTERFERING WITH THE T CELL RECEPTOR-NF-B-GATA-3-IL-4 AXIS WITHOUT A PROMINENT EFFECT ON PARP 1

J. Jordán, A. Boulares, Ji-hang Ju, 2012 .

Common and differential roles of inducible NO synthase and poly (ADP-ribose)polymerase in allergen-induced inflammation and airway hyperresponsiveness: a potential connection to NO levels (HYP5P.320)

A. Naura, K. Pyakurel, Anil Mishra, 2015, The Journal of Immunology.