Hongmin Chen

Identification of predictive genetic signatures of Cytarabine responsiveness using a 3D acute myeloid leukaemia model

I. Kariv, Sarah Javaid, R. Cristescu, 2019, Journal of cellular and molecular medicine.

Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications.

Duan Liu, M. Altman, Ruojing Yang, 2015, Bioorganic & medicinal chemistry letters.

Discovery of 5-Amino-N-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide Inhibitors of IRAK4.

T. Fischmann, M. Altman, Ruojing Yang, 2015, ACS medicinal chemistry letters.

Discovery of 1-(1H-Pyrazolo[4,3-c]pyridin-6-yl)urea Inhibitors of Extracellular Signal-Regulated Kinase (ERK) for the Treatment of Cancers.

G. Naumov, U. Philippar, A. Petrocchi, 2016, Journal of medicinal chemistry.

Establishing and Validating Cellular Functional Target Engagement Assay for Selective IRAK4 Inhibitor Discovery

I. Kariv, Ruojing Yang, Jongwon Lim, 2021, SLAS discovery : advancing life sciences R & D.

Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation.

Duan Liu, T. Fischmann, M. Altman, 2017, Bioorganic & medicinal chemistry letters.

Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction.

M. Crackower, H. Houshyar, Hongshi Yu, 2013, American journal of respiratory cell and molecular biology.

Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation.

Duan Liu, T. Fischmann, M. Altman, 2017, Bioorganic & medicinal chemistry letters.

Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications.

Duan Liu, M. Altman, Ruojing Yang, 2015, Bioorganic & medicinal chemistry letters.