Z. Ashraf

发表

Latest perspectives of orally bioavailable 2,4-diarylaminopyrimidine analogues (DAAPalogues) as anaplastic lymphoma kinase inhibitors: discovery and clinical developments

Muhammad Sohail Zafar, S. Basit, S. Meo, 2018, RSC advances.

Repository In vitro inhibitory evaluation of novel amine and amide compounds against the post-translational modifier enzyme

R. Barnard, J. Zuegg, Christian Fercher, 2019 .

Design, synthesis and docking studies of some novel isocoumarin analogues as antimicrobial agents

A. Saeed, Z. Ashraf, Humaira Nadeem, 2014 .

Quinazolines and quinazolinones as ubiquitous structural fragments in medicinal chemistry: An update on the development of synthetic methods and pharmacological diversification.

A. Saeed, N. Abbas, S. Batool, 2016, Bioorganic & medicinal chemistry.

Synthesis and crystal structures of the potential tyrosinase inhibitors N-(4-acetylphenyl)-2-chloroacetamide and 2-(4-acetylanilino)-2-oxoethyl cinnamate.

S. Kang, S. Seo, Z. Ashraf, 2016, Acta crystallographica. Section C, Structural chemistry.

Kinetic and in silico studies of novel hydroxy-based thymol analogues as inhibitors of mushroom tyrosinase.

M. Rafiq, S. Seo, N. S. Zaidi, 2015, European journal of medicinal chemistry.

Understanding the enzymatic inhibition of intestinal alkaline phosphatase by aminophenazone-derived aryl thioureas with aided computational molecular dynamics simulations: synthesis, characterization, SAR and kinetic profiling

Mubashir Hassan, A. Saeed, Q. Abbas, 2020, Molecular Diversity.

Exploration of Novel Human Tyrosinase Inhibitors by Molecular Modeling, Docking and Simulation Studies

Mubashir Hassan, S. Seo, Q. Abbas, 2016, Interdisciplinary Sciences: Computational Life Sciences.

In Vitro Antibacterial and Antifungal Activity of Methanol, Chloroform and Aqueous Extracts of Origanum vulgare and Their Comparative Analysis

M. Imran, A. H. Tareq, Z. Ashraf, 2011 .

Dexibuprofen amide derivatives as potential anticancer agents: synthesis, in silico docking, bioevaluation, and molecular dynamic simulation

Mubashir Hassan, T. Mahmood, J. Latip, 2019, Drug design, development and therapy.

Synthesis, carbonic anhydrase inhibitory activity and antioxidant activity of some 1,3‐oxazine derivatives

F. Albericio, Mubashir Hassan, A. Saeed, 2018, Drug development research.

Triphenylamine based redox-active, fluorescent polyamides: synthesis and photophysics

N. Khalid, H. Siddiqi, Z. Ashraf, 2020, Journal of Polymer Research.

Design, synthesis and biological evaluation of trinary benzocoumarin-thiazoles-azomethines derivatives as effective and selective inhibitors of alkaline phosphatase.

G. Shabir, J. Sévigny, A. Saeed, 2019, Bioorganic chemistry.

Determinants of Increasing Trend of Self-Medication in a Pakistani Community

H. Khan, R. M. Sarfraz, Z. Ashraf, 2014 .

Antihyperlipidemic studies of newly synthesized phenolic derivatives: in silico and in vivo approaches

Arif-ullah Khan, Z. Ashraf, H. Rafique, 2018, Drug design, development and therapy.

Synthesis, characterization of amide substituted dexibuprofen derivatives and their spectral, voltammetric and docking investigations for DNA binding interactions.

N. Arshad, Fouzia Perveen, Z. Ashraf, 2017, Journal of photochemistry and photobiology. B, Biology.

Synthesis, characterization and in vitro hydrolysis studies of ester and amide prodrugs of dexibuprofen

S. Amin, Muhammad Imran, Z. Ashraf, 2012, Medicinal Chemistry Research.

A Practical Method of N ‐Methylpyrrole Disulfonamides Synthesis: Computational Studies, Carbonic Anhydrase Inhibition and Electrochemical DNA Binding Investigations

Z. Iqbal, Mubashir Hassan, Erum Jabeen, 2021, ChemistrySelect.

Enzyme Inhibitory Kinetics and Molecular Docking Studies of Halo-Substituted Mixed Ester/Amide-Based Derivatives as Jack Bean Urease Inhibitors

Z. Iqbal, Mubashir Hassan, Q. Abbas, 2020, BioMed research international.

In silico approach for the development of phenolic derivatives as potential anti-angiogenic agents against lysyl oxidase-like 2 enzyme

Arif-ullah Khan, Z. Ashraf, Muazzam Arif, 2022, Future Journal of Pharmaceutical Sciences.

Antioxidant Activity and Hepatotoxicity of Flavonoids and Their Metal Complexes Through Co‐Administration of β‐Cyclodextrin

Safeer Ahmed, N. K. Janjua, N. Masood, 2019, ChemistrySelect.

Flurbiprofen–antioxidant mutual prodrugs as safer nonsteroidal anti-inflammatory drugs: synthesis, pharmacological investigation, and computational molecular modeling

H. Ahsan, Mubashir Hassan, Alamgeer, 2016, Drug design, development and therapy.

Multifunctional toxin phospholipase A 2 (PLA 2 ) in Naja oxiana venom a promising target for novel 2,5-disubstituted-1,3,4-oxadiazole derivatives: dry and wet lab approaches

Abdul Mannan, R. Tariq, Fiaz Alam, 2022 .

Novel Penicillin Analogues as Potential Antimicrobial Agents; Design, Synthesis and Docking Studies

U. Niazi, M. Manir, Z. Ashraf, 2015, PloS one.

Synthesis and biological evaluation of substituted aurone derivatives as potential tyrosinase inhibitors: in vitro, kinetic, QSAR, docking and drug-likeness studies.

E. Mughal, Z. Ashraf, Yasir Nazir, 2022, Journal of biomolecular structure & dynamics.

Novel amide derivatives as potent tyrosinase inhibitors; in-vitro, in-vivo antimelanogenic activity and computational studies.

E. Choi, M. Rafiq, G. Lee, 2019, Medicinal chemistry (Shariqah (United Arab Emirates)).

Influence of plasma-activated compounds on melanogenesis and tyrosinase activity

Ji Hoon Park, E. Choi, M. Rafiq, 2016, Scientific Reports.

Synthesis, kinetic mechanism and docking studies of vanillin derivatives as inhibitors of mushroom tyrosinase.

M. Rafiq, S. Seo, N. S. Zaidi, 2015, Bioorganic & medicinal chemistry.

Synthesis , Characterization , Antitumor , Antibacterial and Urease Inhibitory Activity of a Small Series of N-tosyl benzimidazoles 1

M. Rafiq, B. Mirza, J. Jasinski, 2018 .

Metal-catalyzed synthesis of isocoumarin derivatives (microreview)

Z. Ashraf, 2016, Chemistry of Heterocyclic Compounds.

Design, Synthesis and Biological Evaluation of 2‐(naphthoyl) iminothiazolidin‐4‐ones as Potential Anticancer Agents

U. Flörke, A. Saeed, Saba Ashraf, 2020 .

Synthesis, crystal structure and DNA binding interactions of ethyl 2-(2-acetamidothiazol-4-yl) acetate: Theoretical and experimental investigations

Z. Iqbal, R. Z. Paracha, M. Tahir, 2019 .

Iminothiazoline‐Sulfonamide Hybrids as Jack Bean Urease Inhibitors; Synthesis, Kinetic Mechanism and Computational Molecular Modeling

M. Rafiq, A. Saeed, S. Seo, 2016, Chemical biology & drug design.

Synthesis and docking studies of N‐(5‐(alkylthio)‐1,3,4‐oxadiazol‐2‐yl)methyl)benzamide analogues as potential alkaline phosphatase inhibitors

Z. Iqbal, Mubashir Hassan, Z. Ashraf, 2019, Drug development research.

Efficient synthesis of some 3-arylisoquinolin-1(2H)-ones

A. Saeed, Z. Ashraf, 2008 .

Efficient synthesis of some 3-substuited-1(2H)-isoquinolones

A. Saeed, Z. Ashraf, 2008, Pharmaceutical Chemistry Journal.

In Vitro Antimicrobial Activity of Some Novel 3-(Substituted Phenyl) Isocoumarins, 1(2H)-Isoquinolones and Isocoumarin-1-Thiones

A. Saeed, Z. Ashraf, 2014 .

Total synthesis and cytotoxic activity of stellatin

A. Saeed, Z. Ashraf, H. Rafique, 2011, Journal of Asian natural products research.

Synthesis of some 3-aryl-1H-isochromene-1-thiones

A. Saeed, Z. Ashraf, 2008 .

Metal‐Catalyzed Synthesis of Isocoumarin Derivatives (Microreview)

Z. Ashraf, 2016 .

Synthesis and antibacterial evaluation of typharin analog: 6,8-dihydroxy-7-methyl-3-styryl-3,4-dihydroisocoumarin

A. Saeed, Z. Ashraf, H. Rafique, 2013, Journal of Asian natural products research.

Synthesis, Bioevaluation and Molecular Dynamic Simulation Studies of Dexibuprofen–Antioxidant Mutual Prodrugs

Khurram Afzal, Zaman Ashraf, Hongsik Cho, 2016, International journal of molecular sciences.

Synthesis, Biological Evaluation, 2D-QSAR, and Molecular Simulation Studies of Dihydropyrimidinone Derivatives as Alkaline Phosphatase Inhibitors

Muhammad Imran, S. Muhammad, Z. Ashraf, 2022, ACS omega.

Antihyperlipidemic effect of selected pyrimidine derivatives mediated through multiple pathways

N. Irshad, Shupeng Li, Arif-ullah Khan, 2021, Fundamental & clinical pharmacology.

Synthesis of aryl pyrazole via Suzuki coupling reaction, in vitro mushroom tyrosinase enzyme inhibition assay and in silico comparative molecular docking analysis with Kojic acid.

H. El‐Seedi, M. Hasan, A. Saeed, 2018, Bioorganic chemistry.

Synthesis, Biological Evaluation and Molecular Docking Studies of Novel Coumarinylthiazolyl Iminothiazolidinone Hybrids as Potent Urease Inhibitors

A. Saeed, Q. Abbas, Shams-ul Mahmood, 2020 .

First macrocyclic 3rd-generation ALK inhibitor for treatment of ALK/ROS1 cancer: Clinical and designing strategy update of lorlatinib.

Kwangho Lee, Zaman Ashraf, S. Basit, 2017, European journal of medicinal chemistry.

Development of highly potent melanogenesis inhibitor by in vitro, in vivo and computational studies

Mubashir Hassan, S. Seo, Q. Abbas, 2017, Drug design, development and therapy.

4-Aminocoumarin based aroylthioureas as potential jack bean urease inhibitors; Synthesis, enzyme inhibitory kinetics and docking studies.

Mubashir Hassan, A. Saeed, P. A. Channar, 2019, Medicinal chemistry (Shariqah (United Arab Emirates)).

Synthesis, computational studies and enzyme inhibitory kinetics of substituted methyl[2-(4-dimethylamino-benzylidene)-hydrazono)-4-oxo-thiazolidin-5-ylidene]acetates as mushroom tyrosinase inhibitors.

M. Rafiq, A. Saeed, P. A. Channar, 2017, Bioorganic & medicinal chemistry.

Synthesis, enzyme inhibitory kinetics, and computational studies of novel 1‐(2‐(4‐isobutylphenyl) propanoyl)‐3‐arylthioureas as Jack bean urease inhibitors

Mubashir Hassan, A. Saeed, P. A. Channar, 2018, Chemical biology & drug design.

Synthesis, in-vitro, in-vivo anti-inflammatory activities and molecular docking studies of acyl and salicylic acid hydrazide derivatives.

U. Rashid, Rahim Ullah, I. Hussain, 2020, Bioorganic chemistry.

Designing novel anticancer sulfonamide based 2,5-disubstituted-1,3,4-thiadiazole derivatives as potential carbonic anhydrase inhibitor

Z. Iqbal, Mubashir Hassan, S. Iqbal, 2021 .

Design, Synthesis, Crystal Structure, Fluorescence, Molecular Docking and DFT Studies of 3,6-Dinitro-N-octylcarbazole

M. Tayyab, U. Flörke, M. Zafar, 2019, Current Organic Chemistry.

Synthesis and enzyme inhibitory kinetics of some novel 3-(substituted benzoyl)-2-thioxoimidazolidin-4-one derivatives as α-glucosidase/α-amylase inhibitors

A. Saeed, S. Seo, Q. Abbas, 2018, Medicinal Chemistry Research.

Synthesis, DFT, electrochemical, biological and DNA-interaction studies of a novel copper(II) complex of salicylic acid and N-tosyl substituted benzimidazole

M. Rafiq, I. Ahmad, Z. Ashraf, 2020 .

Regiospecific synthesis of some novel N-nucleosides of 4-amino-5-substituted-1,2,4-triazole-3-thiones and their in-vitro antimicrobial activity

Z. Ashraf, Humaira Nadeem, 2012 .

Synthesis, in vitro antibacterial and antifungal activity of some n-acetylated and non-acetylated pyrazolines.

F. Ansari, Z. Ashraf, M. Baseer, 2013, Pakistan journal of pharmaceutical sciences.

Synthesis, Characterization and Antibacterial Activity of New 1,2- and 1,4-Bis(N'-Substituted Thioureido)benzene Derivatives

A. Saeed, N. Abbas, M. Bolte, 2013 .

Substituted phenyl[(5-benzyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetates/acetamides as alkaline phosphatase inhibitors: Synthesis, computational studies, enzyme inhibitory kinetics and DNA binding studies.

Z. Iqbal, Mubashir Hassan, Q. Abbas, 2019, Bioorganic chemistry.

Vibrational spectra and molecular structure of isomeric 1-(adamantan-1-ylcarbonyl)-3-(dichlorophenyl)thioureas

A. Saeed, J. Simpson, Z. Ashraf, 2017 .

Synthesis, density functional theory (DFT) studies and urease inhibition activity of chiral benzimidazoles

Hsin‐Tsung Chen, N. Sathishkumar, Z. Ashraf, 2020, Heliyon.

Synthesis, characterization, biological evaluation and molecular docking studies of N-functionalized derivatives of 2-aminobenzohydrazide

Abdullah M. Asiri, A. Asiri, M. Arshad, 2020, Journal of Molecular Structure.

Isolation, characterization, and in silico, in vitro and in vivo antiulcer studies of isoimperatorin crystallized from Ostericum koreanum

Mubashir Hassan, A. Phull, S. Kang, 2016, Pharmaceutical biology.

Hydroxyl substituted benzoic acid/cinnamic acid derivatives: Tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies.

M. Rafiq, W. M. Hussein, A. Saeed, 2019, Bioorganic & medicinal chemistry letters.

Green Synthesis and Investigation of Surface Effects of α-Fe2O3@TiO2 Nanocomposites by Impedance Spectroscopy

Safina Ghaffar, S. Perveen, A. Shahid, 2022, Materials.

Molecular Docking, Synthesis, and Tyrosinase Inhibition Activity of Acetophenone Amide: Potential Inhibitor of Melanogenesis

S. Shamas, M. Asad, Z. Ashraf, 2022, BioMed Research International.

Methoxy-Substituted Tyramine Derivatives Synthesis, Computational Studies and Tyrosinase Inhibitory Kinetics

Q. Abbas, P. Rachtanapun, K. Jantanasakulwong, 2021, Molecules.

Carvacrol derivatives as mushroom tyrosinase inhibitors; synthesis, kinetics mechanism and molecular docking studies

M. Rafiq, Mubashir Hassan, M. Waseem, 2017, PloS one.

Synthesis, computational studies, tyrosinase inhibitory kinetics and antimelanogenic activity of hydroxy substituted 2-[(4-acetylphenyl)amino]-2-oxoethyl derivatives

M. Rafiq, Mubashir Hassan, Anser Ali, 2019, Journal of enzyme inhibition and medicinal chemistry.

Exploration of Novel Human Tyrosinase Inhibitors by Molecular Modeling, Docking and Simulation Studies

Mubashir Hassan, S. Seo, Q. Abbas, 2016, Interdisciplinary Sciences: Computational Life Sciences.

Design, synthesis and bioevaluation of novel umbelliferone analogues as potential mushroom tyrosinase inhibitors

M. Rafiq, S. Seo, N. S. Zaidi, 2015, Journal of enzyme inhibition and medicinal chemistry.

2-Benzylidenebenzofuran-3(2H)-ones as a new class of alkaline phosphatase inhibitors: synthesis, SAR analysis, enzyme inhibitory kinetics and computational studies

M. Mirzaei, M. Zafar, E. Mughal, 2021, RSC advances.

Crystal structure of 2-(4-acetylanilino)-2-oxoethyl 3-(4-hydroxyphenyl)propionate

S. Kang, S. Seo, Z. Ashraf, 2016, Acta crystallographica. Section E, Crystallographic communications.

Pharmacoinformatics exploration of polyphenol oxidases leading to novel inhibitors by virtual screening and molecular dynamic simulation study

Qamar Abbas, Ahmed A. Moustafa, Mubashir Hassan, 2017, Comput. Biol. Chem..

A review on the Scope of Fluorinated Selective and Reactive TFDO-Mediated Oxidation in Organic Synthesis

H. El‐Seedi, N. Abbas, A. Saeed, 1969 .

Exploring Amantadine Derivatives as Urease Inhibitors: Molecular Docking and Structure–Activity Relationship (SAR) Studies

Mubashir Hassan, A. ul-Hamid, A. Saeed, 2021, Molecules.

Sodium borohydride reduction of aromatic carboxylic acids via methyl esters

A. Saeed, Z. Ashraf, 2006 .

Sulfonamide-Based Azaheterocyclic Schiff Base Derivatives as Potential Carbonic Anhydrase Inhibitors: Synthesis, Cytotoxicity, and Enzyme Inhibitory Kinetics

Z. Iqbal, Mubashir Hassan, A. Rizvanov, 2020, BioMed research international.

Synthesis, characterization and in vitro hydrolysis studies of ester and amide prodrugs of dexibuprofen

S. Amin, Muhammad Imran, Z. Ashraf, 2012, Medicinal Chemistry Research.

THE EFFECT OF CLINICAL RESEARCH CENTER, ON CLINICAL RESEARCHES OF ARAK UNIVERSITY OF MEDICAL SCIENCE

M. Kahbazi, A. Noroozi, Z. Ashraf, 2006 .

Evaluation of 2,3-Dihydro-1,5-benzothiazepine Derivatives as Potential Tyrosinase Inhibitors: In Vitro and In Silico Studies

Saleh A. Ahmed, Z. Moussa, Syed Wadood Ali Shah, 2023, ACS omega.

Succinamide Derivatives Ameliorate Neuroinflammation and Oxidative Stress in Scopolamine-Induced Neurodegeneration

Muhammad Imran, Shupeng Li, Z. Ashraf, 2020, Biomolecules.

Polyimides with noncoplanar Carbazole-TPA units: synthesis and characterization

N. K. Janjua, M. Zubair, A. Iqbal, 2020 .

Novel 5‐Acetyl‐3‐aryl‐2‐thioxo‐dihydropyrimidine‐4,6(1H,5H)‐diones: One Pot Three‐Component Synthesis, Characterization and Antibacterial Activity

A. Saeed, N. Abbas, M. Bolte, 2014 .

2-Chloro-5-nitroaniline

Michael Bolte, Aamer Saeed, Mahira Batool, 2009, Acta crystallographica. Section E, Structure reports online.

An investigation of supramolecular synthons in 1,2,4-triazole-3(4H)-thione compounds. X-ray crystal structures, energetic and Hirshfeld surface analysis

A. Saeed, J. Simpson, Z. Ashraf, 2019, Journal of Molecular Structure.

Synthesis, Computational Studies, Antioxidant and Anti-Inflammatory Bio-Evaluation of 2,5-Disubstituted-1,3,4-Oxadiazole Derivatives

H. Saeed, Z. Ashraf, H. Rafique, 2023, Pharmaceuticals.

Charge transfer and opto-electronic properties of some newly designed polycatenar discotic liquid crystal derivatives: a DFT study

T. Noor, Fouzia Perveen, Z. Ashraf, 2020, Journal of Molecular Modeling.

Finding Novel Anti-carcinomas Compounds by Targeting SFRP4 Through Molecular Modeling, Docking and Dynamic Simulation Studies.

A. Moustafa, S. Seo, Q. Abbas, 2018, Current computer-aided drug design.

Cardioprotective effect of 2-methoxy phenol derivatives against oxidative stress-induced vascular complications: An integrated in vitro, in silico, and in vivo investigation.

S. Bungău, Nisar-ur Rahman, Arif-ullah Khan, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Synthesis, Characterization, Anti-Inflammatory and in Vitro Antimicrobial Activity of Some Novel Alkyl/Aryl Substituted Tertiary Alcohols

F. Ansari, Z. Ashraf, M. Baseer, 2011, Molecules.