T. Uno

发表

Fixed eruption due to quinine in tonic water: A case report with high‐performance liquid chromatography and ultraviolet A analyses

T. Miyagi, H. Uezato, Sayaka Yamaguchi, 2013, The Journal of dermatology.

Effect of clarithromycin on the enantioselective disposition of lansoprazole in relation to CYP2C19 genotypes.

N. Yasui-Furukori, M. Miura, Toshio Suzuki, 2005, Chirality.

The (R)-omeprazole hydroxylation index reflects CYP2C19 activity in healthy Japanese volunteers

N. Yasui-Furukori, Y. Akamine, S. Yamada, 2013, European Journal of Clinical Pharmacology.

Hydroxylation of R(+)- and S(−)-Omeprazole after Racemic Dosing are Different among the CYP2C19 Genotypes

N. Yasui-Furukori, Y. Akamine, S. Yamada, 2012, Pharmaceutical Research.

Chiral assay of omeprazole and metabolites and its application to a pharmacokinetics related to CYP2C19 genotypes.

N. Yasui-Furukori, H. Shiohira, T. Uno, 2011, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Absolute bioavailability and metabolism of omeprazole in relation to CYP2C19 genotypes following single intravenous and oral administrations

M. Hayakari, N. Yasui-Furukori, T. Niioka, 2007, European Journal of Clinical Pharmacology.

The effect of CYP2C19 genotypes on the pharmacokinetics of warfarin enantiomers

K. Sugimoto, T. Uno, T. Tateishi, 2008, Journal of clinical pharmacy and therapeutics.

Effects of multiple‐dose rifampicin 450 mg on the pharmacokinetics of fexofenadine enantiomers in Japanese volunteers

N. Yasui-Furukori, M. Miura, I. Ieiri, 2015, Journal of Clinical Pharmacy and Therapeutics.

Effects of repeated ingestion of grapefruit juice on the single and multiple oral-dose pharmacokinetics and pharmacodynamics of alprazolam

K. Otani, S. Kaneko, T. Kondo, 2000, Psychopharmacology.

Effects of grapefruit juice on the stereoselective disposition of nicardipine in humans: evidence for dominant presystemic elimination at the gut site

T. Ishizaki, S. Motomura, T. Uno, 2000, European Journal of Clinical Pharmacology.

Lack of Significant Effect of Grapefruit Juice on the Pharmacokinetics of Lansoprazole and Its Metabolites in Subjects With Different CYP2C19 Genotypes

T. Uno, T. Takahata, T. Tateishi, 2005, Journal of clinical pharmacology.

Effect of grapefruit juice on the disposition of manidipine enantiomers in healthy subjects.

S. Motomura, T. Uno, K. Sugawara, 2006, British journal of clinical pharmacology.

Intestinal CYP3A4 is not involved in the enantioselective disposition of lansoprazole

N. Yasui-Furukori, M. Miura, H. Kagaya, 2006, Xenobiotica; the fate of foreign compounds in biological systems.

Estimation of CYP2C19 activity by the omeprazole hydroxylation index at a single point in time after intravenous and oral administration

M. Hayakari, K. Sugimoto, T. Niioka, 2007, European Journal of Clinical Pharmacology.

Enantioselective disposition of lansoprazole in relation to CYP2C19 genotypes in the presence of fluvoxamine.

N. Yasui-Furukori, M. Miura, Toshio Suzuki, 2005, British journal of clinical pharmacology.

Effects of clarithromycin on lansoprazole pharmacokinetics between CYP2C19 genotypes.

A. Munakata, N. Yasui-Furukori, T. Uno, 2005, British journal of clinical pharmacology.

Influence of drug-transporter polymorphisms on the pharmacokinetics of fexofenadine enantiomers

N. Yasui-Furukori, M. Miura, H. Kagaya, 2010, Xenobiotica; the fate of foreign compounds in biological systems.

Effects of the P-glycoprotein Inducer Carbamazepine on Fexofenadine Pharmacokinetics

N. Yasui-Furukori, S. Kaneko, Y. Akamine, 2009, Therapeutic drug monitoring.

Effects of itraconazole and diltiazem on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein.

Mikiko Shimizu, T. Uno, T. Tateishi, 2006, British journal of clinical pharmacology.

Personalized Medicine of Antithrombotic Therapy

T. Uno, S. Yamada, 2013 .

Pharmacokinetics of low-dose nedaplatin and validation of AUC prediction in patients with non-small-cell lung carcinoma

N. Yasui-Furukori, T. Niioka, Mikiko Shimizu, 2007, Cancer Chemotherapy and Pharmacology.

Effects of selective serotonin reuptake inhibitors on the pharmacokinetics of proton pump inhibitors

N. Yasui-Furukori, Y. Akamine, T. Hirano, 2017 .

The Role of Cytochrome P2C19 in R-warfarin Pharmacokinetics and its Interaction With Omeprazole

K. Sugimoto, T. Uno, T. Tateishi, 2008, Therapeutic drug monitoring.

Different effects of fluvoxamine on rabeprazole pharmacokinetics in relation to CYP2C19 genotype status.

N. Yasui-Furukori, Mikiko Shimizu, T. Uno, 2006, British journal of clinical pharmacology.

Determination of lansoprazole and two of its metabolites by liquid-liquid extraction and automated column-switching high-performance liquid chromatography: application to measuring CYP2C19 activity.

N. Yasui-Furukori, T. Uno, T. Takahata, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Simultaneous Determination of Warfarin Enantiomers and Its Metabolite in Human Plasma by Column-Switching High-Performance Liquid Chromatography With Chiral Separation

M. Hayakari, T. Niioka, T. Uno, 2007, Therapeutic drug monitoring.

The Role of Drug Transporters on Psychotropic Penetration of the Blood–Brain Barrier

Y. Akamine, T. Uno, K. China, 2012 .

Effects of single and multiple doses of itraconazole on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein.

Mikiko Shimizu, T. Uno, T. Tateishi, 2006, British journal of clinical pharmacology.

Limited frequency of the CYP2C19*17 allele and its minor role in a Japanese population.

H. Yamazaki, K. Sugimoto, T. Uno, 2008, British journal of clinical pharmacology.

A developed determination of midazolam and 1'-hydroxymidazolam in plasma by liquid chromatography-mass spectrometry: application of human pharmacokinetic study for measurement of CYP3A activity.

H. Kanazawa, Mikiko Shimizu, T. Uno, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Am80 induces neuronal differentiation via increased tropomyosin-related kinase B expression in a human neuroblastoma SH-SY5Y cell line.

M. Nakashima, M. Enjoji, T. Uno, 2012, Biomedical research.

Lack of Dose-Dependent Effects of Itraconazole on the Pharmacokinetic Interaction with Fexofenadine

Mikiko Shimizu, T. Uno, T. Tateishi, 2006, Drug Metabolism and Disposition.

interaction with fexofenadine

Mikiko Shimizu, T. Uno, K. Sugawara, 2006 .

Clinical pharmacokinetics of fexofenadine enantiomers

M. Miura, T. Uno, 2010, Expert opinion on drug metabolism & toxicology.

Oral Administration of IL-12 Abrogates the Induction but Not the Maintenance of Oral Tolerance

Koji Takahashi, M. Hattori, Tadashi Yoshida, 2006, International Archives of Allergy and Immunology.

Influence of Genetic Polymorphisms and Non-Genetic Factors upon Warfarin Maintenance Dose in Japanese Elderly Patients

H. Nakashima, T. Uno, J. Miura, 2011 .

Enantioselective disposition of rabeprazole in relation to CYP2C19 genotypes.

N. Yasui-Furukori, M. Miura, H. Kagaya, 2006, British journal of clinical pharmacology.

PHARMACOKINETICS A ND D ISPOSITION

M. Miura, Toshio Suzuki, H. Tada, 2002 .

Determination of rabeprazole and its active metabolite, rabeprazole thioether in human plasma by column-switching high-performance liquid chromatography and its application to pharmacokinetic study.

N. Yasui-Furukori, Mikiko Shimizu, T. Uno, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Pharmacokinetic differences between the enantiomers of lansoprazole and its metabolite, 5-hydroxylansoprazole, in relation to CYP2C19 genotypes

M. Miura, H. Tada, T. Uno, 2004, European Journal of Clinical Pharmacology.

Multiple inductive effects of carbamazepine on combined therapy with paliperidone and amlodipine

M. Miura, Y. Akamine, T. Uno, 2015, Journal of clinical pharmacy and therapeutics.

Sensitive Determination of Itraconazole and Its Active Metabolite in Human Plasma by Column-switching High-performance Liquid Chromatography With Ultraviolet Detection

Mikiko Shimizu, T. Uno, T. Tateishi, 2006, Therapeutic drug monitoring.

The different effects of itraconazole on the pharmacokinetics of fexofenadine enantiomers.

M. Miura, Toshio Suzuki, T. Uno, 2008, British journal of clinical pharmacology.

The change of pharmacokinetics of fexofenadine enantiomers through the single and simultaneous grapefruit juice ingestion.

N. Yasui-Furukori, I. Tamai, M. Miura, 2015, Drug metabolism and pharmacokinetics.

Effects of one-time apple juice ingestion on the pharmacokinetics of fexofenadine enantiomers

H. Kusuhara, I. Tamai, M. Miura, 2014, European Journal of Clinical Pharmacology.

Effect of Coadministration of Single and Multiple Doses of Rifampicin on the Pharmacokinetics of Fexofenadine Enantiomers in Healthy Subjects

H. Kusuhara, Y. Sugiyama, N. Yasui-Furukori, 2013, Drug Metabolism and Disposition.

DMD048330 206..213

H. Kusuhara, Y. Sugiyama, M. Miura, 2012 .

Enantioselective disposition of fexofenadine with the P-glycoprotein inhibitor verapamil.

M. Miura, Toshio Suzuki, T. Uno, 2009, British journal of clinical pharmacology.

Pharmacokinetics of fexofenadine enantiomers in healthy subjects.

M. Miura, Toshio Suzuki, T. Uno, 2007, Chirality.

Determination of fexofenadine enantiomers in human plasma with high-performance liquid chromatography.

M. Miura, Toshio Suzuki, T. Uno, 2007, Journal of pharmaceutical and biomedical analysis.

Liquid chromatographic determination of manidipine in serum with electrochemical detection.

T. Uno, K. Sugawara, T. Ohkubo, 1996, Journal of chromatography. B, Biomedical applications.

Carbamazepine differentially affects the pharmacokinetics of fexofenadine enantiomers.

N. Yasui-Furukori, M. Miura, Y. Akamine, 2012, British journal of clinical pharmacology.

Different Effects of Three Transporting Inhibitors, Verapamil, Cimetidine, and Probenecid, on Fexofenadine Pharmacokinetics

N. Yasui-Furukori, Kazunobu Sugawara, Norio Yasui-Furukori, 2005, Clinical pharmacology and therapeutics.

Drug-Drug Interactions of P-gp Substrates Unrelated to CYP Metabolism.

N. Yasui-Furukori, Y. Akamine, T. Uno, 2019, Current drug metabolism.

Liquid chromatographic determination of fexofenadine in human plasma with fluorescence detection.

T. Uno, T. Takahata, T. Tateishi, 2004, Journal of pharmaceutical and biomedical analysis.

Column-switching high-performance liquid chromatography of ofloxacin in human saliva and correlation of ofloxacin level in saliva and serum.

T. Uno, K. Sugawara, T. Ohkubo, 1996, Therapeutic Drug Monitoring.

Determination of Propylthiouracil in Human Breast Milk by Direct Injection High Performance Liquid Chromatography

T. Uno, K. Sugawara, T. Ohkubo, 1991 .

Sensitive determination of omeprazole and its two main metabolites in human plasma by column-switching high-performance liquid chromatography: application to pharmacokinetic study in relation to CYP2C19 genotypes.

T. Niioka, Mikiko Shimizu, T. Uno, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Effects of a dopamine receptor agonist and atropine sulfate on absorption of valproic acid in rats.

N. Hobara, T. Uno, N. Hokama, 2009, Biomedical research.

A sensitive column-switching HPLC method for aripiprazole and dehydroaripiprazole and its application to human pharmacokinetic studies.

Y. Akamine, Y. Inoue, T. Uno, 2010, Journal of separation science.

Effects of clarithromycin and verapamil on rabeprazole pharmacokinetics between CYP2C19 genotypes

Mikiko Shimizu, T. Uno, T. Tateishi, 2006, European Journal of Clinical Pharmacology.

Quantification of the steady-state plasma concentrations of clozapine and N-desmethylclozapine in Japanese patients with schizophrenia using a novel HPLC method and the effects of CYPs and ABC transporters polymorphisms

M. Miura, Y. Akamine, T. Uno, 2017, Annals of clinical biochemistry.

Psychotropic Drug–Drug Interactions Involving P-Glycoprotein

N. Yasui-Furukori, I. Ieiri, Y. Akamine, 2012, CNS Drugs.

Effects of Fluvoxamine on Lansoprazole Pharmacokinetics in Relation to CYP2C19 Genotypes

T. Uno, T. Takahata, T. Tateishi, 2004, Journal of clinical pharmacology.

Identification of a Single Time-point for Plasma Lansoprazole Measurement That Adequately Reflects Area Under the Concentration-Time Curve

T. Niioka, S. Kaneko, T. Uno, 2006, Therapeutic drug monitoring.

Estimation of the area under the concentration-time curve of racemic lansoprazole by using limited plasma concentration of lansoprazole enantiomers

M. Hayakari, M. Miura, T. Niioka, 2008, European Journal of Clinical Pharmacology.

Fexofenadine does not affect omeprazole pharmacokinetics: both are putative P-glycoprotein substrates.

T. Uno, T. Takahata, T. Tateishi, 2004, Basic & clinical pharmacology & toxicology.

Patient factors against stable control of warfarin therapy for Japanese non-valvular atrial fibrillation patients.

Koujirou Yamamoto, M. Usui, S. Ando, 2013, Thrombosis research.

Standard warfarin dose in a patient with the CYP2C9*3/*3 genotype leads to hematuria.

Koujirou Yamamoto, M. Miura, Y. Abe, 2010, Clinica chimica acta; international journal of clinical chemistry.

Effect of grapefruit juice in relation to human pharmacokinetic study.

N. Yasui-Furukori, T. Uno, N. Yasui‐Furukori, 2006, Current clinical pharmacology.

Effects of the CYP3A5 genotype on omeprazole sulfoxidation in CYP2C19 PMs

K. Sugimoto, T. Uno, T. Tateishi, 2008, European Journal of Clinical Pharmacology.

Different Effects of the Selective Serotonin Reuptake Inhibitors Fluvoxamine, Paroxetine, and Sertraline on the Pharmacokinetics of Fexofenadine in Healthy Volunteers

T. Niioka, J. Saruwatari, S. Kaneko, 2012, Journal of clinical psychopharmacology.

Enantiomer separation of dihydropyridine derivatives by liquid chromatography with chiral stationary phase

T. Uno, K. Sugawara, T. Ohkubo, 1992 .

The (R)-omeprazole hydroxylation index reflects CYP2C19 activity in healthy Japanese volunteers

Y. Akamine, S. Yamada, H. Shiohira, 2013, European Journal of Clinical Pharmacology.

Effects of one-time apple juice ingestion on the pharmacokinetics of fexofenadine enantiomers

H. Kusuhara, N. Yasui-Furukori, I. Tamai, 2014, European Journal of Clinical Pharmacology.

Oral Administration of Alginic Acid Oligosaccharide Suppresses IgE Production and Inhibits the Induction of Oral Tolerance

M. Hattori, Tadashi Yoshida, T. Uno, 2006, Bioscience, biotechnology, and biochemistry.

Enantioselective high-performance liquid chromatographic determination of nicardipine in human plasma.

T. Uno, K. Sugawara, T. Ohkubo, 1997, Journal of chromatography. B, Biomedical sciences and applications.

ENANTIOSELECTIVE HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF MANIDIPINE IN HUMAN PLASMA

T. Uno, K. Sugawara, T. Ohkubo, 1999 .

Identification of the time-point which gives a plasma rabeprazole concentration that adequately reflects the area under the concentration-time curve

T. Niioka, Mikiko Shimizu, T. Uno, 2006, European Journal of Clinical Pharmacology.

Effects of the CYP2D6*10 Allele on the Steady-State Plasma Concentrations of Aripiprazole and Its Active Metabolite, Dehydroaripiprazole, in Japanese Patients With Schizophrenia

K. Nemoto, T. Kondo, T. Uno, 2011, Therapeutic drug monitoring.

Different Effects of the Selective Serotonin Reuptake Inhibitors Fluvoxamine, Paroxetine, and Sertraline on the Pharmacokinetics of Fexofenadine in Healthy Volunteers

N. Yasui-Furukori, T. Niioka, J. Saruwatari, 2012, Journal of clinical psychopharmacology.