Omid Motabar

发表

High Throughput Screening for Inhibitors of Alpha-Galactosidase

Noel Southall, Wei Zheng, J. Marugan, 2010, Current chemical genomics.

Synergistic drug combination effectively blocks Ebola virus infection

P. Shinn, Wei Zheng, X. Qiu, 2017, Antiviral research.

Non-iminosugar glucocerebrosidase small molecule chaperones.

Noel Southall, A. Simeonov, Jingbo Xiao, 2012, MedChemComm.

Discovery of a novel non-iminosugar acid alpha glucosidase chaperone series

Ellen, Noel Southall, R. Tamargo, 2012 .

Synthesis and characterization of a new fluorogenic substrate for alpha-galactosidase

Noel Southall, C. Austin, Wei Zheng, 2009, Analytical and bioanalytical chemistry.

Discovery, SAR, and Biological Evaluation of Non-inhibitory Chaperones of Glucocerebrosidase

Noel Southall, Wei Zheng, J. Marugan, 2013 .

A high throughput glucocerebrosidase assay using the natural substrate glucosylceramide

Noel Southall, Wei Zheng, J. Marugan, 2011, Analytical and Bioanalytical Chemistry.

Evaluation of quinazoline analogues as glucocerebrosidase inhibitors with chaperone activity.

Christopher P Austin, Anton Simeonov, Noel Southall, 2011, Journal of medicinal chemistry.

Discovery, structure-activity relationship, and biological evaluation of noninhibitory small molecule chaperones of glucocerebrosidase.

Noel Southall, Wei Zheng, J. Marugan, 2012, Journal of medicinal chemistry.

A new resorufin-based alpha-glucosidase assay for high-throughput screening.

Noel Southall, C. Austin, Wei Zheng, 2009, Analytical biochemistry.

Fabry Disease – Current Treatment and New Drug Development

Wei Zheng, E. Sidransky, Omid Motabar, 2010, Current chemical genomics.

High Throughput Screening for Small Molecule Therapy for Gaucher Disease Using Patient Tissue as the Source of Mutant Glucocerebrosidase

Noel Southall, C. Austin, Wei Zheng, 2012, PloS one.

Small Molecule Drug Discovery for Fabry Disease

Wei Zheng, E. Sidransky, Omid Motabar, 2010 .

Disease models for the development of therapies for lysosomal storage diseases

M. Ferrer, Wei Zheng, J. Marugan, 2016, Annals of the New York Academy of Sciences.

Discovery of a novel noniminosugar acid α glucosidase chaperone series.

M. Ferrer, Noel Southall, R. Tamargo, 2012, Journal of medicinal chemistry.

Evaluation of 2-thioxo-2,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidin-4(1H)-one analogues as GAA activators.

Noel Southall, C. Austin, Wei Zheng, 2010, European journal of medicinal chemistry.

Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease

Wei Zheng, J. Marugan, D. Ory, 2018, Orphanet Journal of Rare Diseases.

Identification of Modulators of the N370S Mutant Form of Glucocerebrosidase as a Potential Therapy for Gaucher Disease - Chemotype 2

Noel Southall, Wei Zheng, J. Marugan, 2011 .