Y. Shaaltiel

发表

Crystal structures of complexes of N-butyl- and N-nonyl-deoxynojirimycin bound to acid beta-glucosidase: insights into the mechanism of chemical chaperone action in Gaucher disease.

Joel L Sussman, Israel Silman, J. Sussman, 2007, The Journal of biological chemistry.

Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system.

O. Dym, J. Sussman, I. Silman, 2007, Plant biotechnology journal.

Characterization of a chemically modified plant cell culture expressed human α-Galactosidase-A enzyme for treatment of Fabry disease.

Yoram Tekoah, D. Aviezer, Yaniv Azulay, 2015, Molecular genetics and metabolism.

An oral administration of a recombinant anti-TNF fusion protein is biologically active in the gut promoting regulatory T cells: Results of a phase I clinical trial using a novel oral anti-TNF alpha-based therapy.

E. Almon, Y. Ilan, T. Khoury, 2017, Journal of immunological methods.

Novel Orally Administered Recombinant Anti-TNF Alpha Fusion Protein for the Treatment of Ulcerative Colitis

E. Almon, Y. Ilan, M. Waterman, 2020, Journal of clinical gastroenterology.

A plant cell-expressed recombinant anti-TNF fusion protein is biologically active in the gut and alleviates immune-mediated hepatitis and colitis.

E. Almon, Y. Ilan, Y. Shaaltiel, 2017, Immunobiology.

Transfer of antibodies elicited by baculovirus-derived VP2 of a very virulent bursal disease virus strain to progeny of commercial breeder chickens

J. Pitcovski, B. Levi, M. Goldway, 2000, Avian pathology : journal of the W.V.P.A.

Taliglucerase alfa: an enzyme replacement therapy using plant cell expression technology.

G. Grabowski, M. Golembo, Y. Shaaltiel, 2014, Molecular genetics and metabolism.

Glycosylation and functionality of recombinant β-glucocerebrosidase from various production systems

Yoram Tekoah, D. Aviezer, M. Golembo, 2013, Bioscience reports.

Cross tolerance to herbicidal and environmental oxidants of plant biotypes tolerant to paraquat, sulfur dioxide, and ozone

J. Gressel, Y. Shaaltiel, A. Glazer, 1988 .

Light-requiring acifluorfen action in the absence of bulk photosynthetic pigments

A. Ben‐Amotz, J. Gressel, V. Gaba, 1988 .

Mode of Evolved Photooxidant Resistance to Herbicides and Xenobiotics

M. Jansen, J. Gressel, C. Malan, 1990 .

Coding region of segment A sequence of a very virulent isolate of IBDV--comparison with isolates from different countries and virulence.

T. Maray, J. Pitcovski, B. Levi, 1998, Avian diseases.

Insect cell-derived VP2 of infectious bursal disease virus confers protection against the disease in chickens.

J. Pitcovski, B. Levi, Y. Shaaltiel, 1996, Avian diseases.

Cyclodextrin-mediated crystallization of acid β-glucosidase in complex with amphiphilic bicyclic nojirimycin analogues.

J. Sussman, I. Silman, J. M. Benito, 2011, Organic & biomolecular chemistry.

6‐Amino‐6‐deoxy‐5,6‐di‐N‐(N′‐octyliminomethylidene)nojirimycin: Synthesis, Biological Evaluation, and Crystal Structure in Complex with Acid β‐Glucosidase

J. Sussman, I. Silman, C. Ortiz Mellet, 2009, Chembiochem : a European journal of chemical biology.

A Plant-Derived Recombinant Human Glucocerebrosidase Enzyme—A Preclinical and Phase I Investigation

E. Galun, S. Hashmueli, D. Aviezer, 2009, PloS one.

9. Novel enzyme replacement therapy for Gaucher disease: Phase III pivotal clinical trial with plant cell expressed recombinantglucocerebrosidase (prGCD) – taliglucerase alpha

S. Hashmueli, D. Aviezer, A. Zimran, 2010 .

Plant-based oral delivery of β-glucocerebrosidase as an enzyme replacement therapy for Gaucher's disease.

Yoram Tekoah, D. Aviezer, Y. Shaaltiel, 2015, Plant biotechnology journal.

Establishment of a tobacco BY2 cell line devoid of plant‐specific xylose and fucose as a platform for the production of biotherapeutic proteins

Yoram Tekoah, M. Weiss, Yaniv Azulay, 2017, Plant biotechnology journal.

Large-scale production of pharmaceutical proteins in plant cell culture-the Protalix experience.

Yoram Tekoah, D. Bartfeld, Y. Shaaltiel, 2015, Plant biotechnology journal.

Preclinical and first-in-human evaluation of PRX-105, a PEGylated, plant-derived, recombinant human acetylcholinesterase-R.

H. Soreq, T. Ben-Moshe, J. Atsmon, 2015, Toxicology and applied pharmacology.

Oral administration of a non-absorbable plant cell-expressed recombinant anti-TNF fusion protein induces immunomodulatory effects and alleviates nonalcoholic steatohepatitis

E. Almon, Y. Ilan, Y. Shaaltiel, 2016, World journal of gastroenterology.

Glycosylation and functionality of recombinant glucocerebrosidase from various production systems

D. Aviezer, Y. Shaaltiel, Mariana Hainrichson, 2014 .

Development and Analytical Characterization of Pegunigalsidase Alfa, a Chemically Cross-Linked Plant Recombinant Human α-Galactosidase-A for Treatment of Fabry Disease.

Yoram Tekoah, Yaniv Azulay, Y. Shaaltiel, 2018, Bioconjugate chemistry.

Plant specific N-glycans do not have proven adverse effects in humans

Yoram Tekoah, Y. Shaaltiel, 2016, Nature Biotechnology.

Sequential Genome Editing and Induced Excision of the Transgene in N. tabacum BY2 Cells

Yoram Tekoah, Y. Shaaltiel, U. Hanania, 2020, Frontiers in Plant Science.

Plant-based oral delivery of β-glucocerebrosidase as an enzyme replacement therapy for Gaucher's disease.

Yoram Tekoah, D. Aviezer, Y. Shaaltiel, 2015, Plant biotechnology journal.

Crystal Structures of Complexes of N-Butyl- and N-Nonyl-Deoxynojirimycin Bound to Acid β-Glucosidase

J. Sussman, I. Silman, T. Butters, 2007, Journal of Biological Chemistry.