Lihren Chen

发表

Synthesis and Evaluation of Homoaza Sugars as Glycosidase Inhibitors

Chi‐Huey Wong, J. Porco, L. Provencher, 1995 .

Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib.

J. D. Clark, M. Hegen, J. McKew, 2008, Journal of medicinal chemistry.

Synthesis of C1C8 and C9C24 fragments of (−)-discodermolide: use of asymmetric alkylation and stereoselective aldol reactions☆

Jinhua J. Song, S. Masamune, S. Filla, 1999 .

Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2alpha: optimization of in vitro potency and rat pharmacokinetics for oral efficacy.

J. D. Clark, J. McKew, W. Abraham, 2008, Bioorganic & medicinal chemistry.

Structure-activity studies of a series of dipyrazolo[3,4-b:3',4'-d]pyridin-3-ones binding to the immune regulatory protein B7.1.

Jing Chen, J. Xiang, D. Erbe, 2003, Bioorganic & medicinal chemistry.

Palladium-mediated stereocontrolled reductive amination of azido sugars prepared from enzymic aldol condensation: a general approach to the synthesis of deoxy aza sugars

Chi‐Huey Wong, K. Liu, T. Kajimoto, 1991 .

Use of dihydroxyacetone phosphate-dependent aldolases in the synthesis of deoxy aza sugars

Chi‐Huey Wong, K. Liu, Y. Ichikawa, 1991 .

Facile and successive orthometallation in rhenium carbene complex

K. Lu, Y. Wen, Lihren Chen, 1993 .

Enzymes in organic synthesis: synthesis of highly enantiomerically pure 1,2-epoxy aldehydes, epoxy alcohols, thiirane, aziridine, and glyceraldehyde 3-phosphate

Richard L. Pederson, Chi‐Huey Wong, K. Liu, 1990 .

Developing better enzymes for organic synthesis.

Chi‐Huey Wong, K. Liu, Y. Ichikawa, 1992 .

Recombinant 2-Deoxyribose-5-phosphate Aldolase in Organic Synthesis: Use of Sequential Two-Substrate and Three-Substrate Aldol Reactions

Chi‐Huey Wong, E. García-Junceda, Lihren Chen, 1995 .

Deoxyribose-5-phosphate Aldolase as a Catalyst in Asymmetric Aldol Condensation.

Chi-Huey Wong, Chi‐Huey Wong, D. Dumas, 1992 .

Reactions of functionalized sulfonamides: application to lowering the lipophilicity of cytosolic phospholipase A2alpha inhibitors.

J. McKew, E. A. Murphy, Xingwei Xu, 2009, Journal of medicinal chemistry.

Discovery of Ecopladib, an Indole Inhibitor of Cytosolic Phospholipase Α2α

S. Khor, J. D. Clark, J. McKew, 2007 .

Discovery of Ecopladib, an indole inhibitor of cytosolic phospholipase A2alpha.

S. Khor, J. McKew, M. S. Ku, 2007, Journal of medicinal chemistry.

A New Route to Deoxythio sugars Based on Aldolases

Chi‐Huey Wong, Jim-Min Fang, Lihren Chen, 1994 .

A New Route to Deoxythiosugars Based on Aldolases.

Chi‐Huey Wong, Jim-Min Fang, Lihren Chen, 1994 .

Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model.

J. McKew, T. Mansour, J. Xiang, 2008, Journal of medicinal chemistry.

Crystallization and preliminary crystallographic data for class I deoxyribose‐5‐phosphate aldolase from Escherichia coli: An Application of Reverse Screening

I. Wilson, Chi‐Huey Wong, E. Stura, 1995, Proteins.