D. Karnak

发表

Translation of DNA damage response inhibitors as chemoradiation sensitizers from the laboratory to the clinic.

A. Rehemtulla, T. Lawrence, H. Willers, 2021, International journal of radiation oncology, biology, physics.

Molecular Medicine in Practice Cotargeting MAPK and PI 3 K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cancer

B. Ross, A. Rehemtulla, T. Lawrence, 2012 .

Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination Repair12

T. Lawrence, J. Maybaum, Mary A Davis, 2015, Neoplasia.

Combined Inhibition of Wee1 and PARP1/2 for Radiosensitization in Pancreatic Cancer

T. Lawrence, J. Maybaum, Mary A Davis, 2014, Clinical Cancer Research.

A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2–Beclin1 interaction at endoplasmic reticulum

T. Lawrence, X. Wu, F. He, 2011, Cell Death and Differentiation.

Improved prediction of radiation pneumonitis by combining biological and radiobiological parameters using a data-driven Bayesian network analysis

S. Jolly, P. Boonstra, Yilun Sun, 2022, Translational oncology.

The Bcl-2-Beclin 1 interaction in (-)-gossypol-induced autophagy versus apoptosis in prostate cancer cells

Liang Xu, J. Lian, D. Karnak, 2010, Autophagy.

TNFR1 and the TNFα axis as a targetable mediator of liver injury from stereotactic body radiation therapy

R. T. Ten Haken, M. Schipper, T. Lawrence, 2020, Translational oncology.

Cervical mucins carry α(1,2)fucosylated glycans that partly protect from experimental vaginal candidiasis

M. Bäckström, S. Domino, G. Hansson, 2009, Glycoconjugate Journal.

Identification of Multiple Binding Partners for the Amino-terminal Domain of Synapse-associated Protein 97*

B. Margolis, D. Karnak, Seonok Lee, 2002, The Journal of Biological Chemistry.

Cancer Therapy : Preclinical Sensitization of Pancreatic Cancer to Chemoradiation by the Chk 1 Inhibitor MK 8776

Daria M. Tanska, T. Lawrence, J. Maybaum, 2013 .

Identification of an Evolutionarily Conserved Heterotrimeric Protein Complex Involved in Protein Targeting*

Dallas E. Kroon, Stuart K. Kim, B. Margolis, 1998, The Journal of Biological Chemistry.

mLin-7 is localized to the basolateral surface of renal epithelia via its NH(2) terminus.

B. Margolis, J. Wade, J. Borg, 2000, American journal of physiology. Renal physiology.

Cell Surface Fucosylation Does Not Affect Development of Colon Tumors in Mice with Germline Smad3 Mutation

S. Domino, Elizabeth A. Hurd, D. Karnak, 2007, Tumor Biology.

Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair

T. Lawrence, Yi Sun, J. Maybaum, 2013, Clinical Cancer Research.

Cotargeting MAPK and PI3K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cancer

B. Ross, A. Rehemtulla, T. Lawrence, 2012, Molecular Cancer Therapeutics.

Sensitization of Pancreatic Cancer to Chemoradiation by the Chk1 Inhibitor MK8776

Daria M. Tanska, T. Lawrence, J. Maybaum, 2013, Clinical Cancer Research.

Chemosensitization of prostate cancer by modulating Bcl-2 family proteins.

Liang Xu, D. Karnak, 2010, Current drug targets.

A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells.

E. Yoon, A. Bild, I. Kovalenko, 2019, Cell reports.

FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4.

T. Lawrence, Yi Sun, M. Tan, 2016, Molecular cell.

HAb18G/CD147 Promotes pSTAT3-Mediated Pancreatic Cancer Development via CD44s

T. Lawrence, Jiayuh Lin, Liang Xu, 2013, Clinical Cancer Research.

Serum Levels of Hepatocyte Growth Factor and CD40 Ligand Predict Radiation-Induced Liver Injury123

Yilun Sun, M. Schipper, I. El Naqa, 2019, Translational oncology.

Wee1 Kinase Inhibitor AZD1775 Radiosensitizes Hepatocellular Carcinoma Regardless of TP53 Mutational Status Through Induction of Replication Stress.

T. Lawrence, J. Maybaum, Mary A Davis, 2016, International journal of radiation oncology, biology, physics.

PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors

T. Lawrence, M. O’Connor, J. Maybaum, 2017, Molecular Cancer Research.

Interaction with mLin-7 alters the targeting of endocytosed transmembrane proteins in mammalian epithelial cells.

B. Margolis, L. Chen, S. Straight, 2001, Molecular biology of the cell.

Molecular Cloning and Characterization of Pals, Proteins Associated with mLin-7*

B. Margolis, E. Kamberov, S. Straight, 2000, The Journal of Biological Chemistry.

Title : Co-Targeting MAPK and PI 3 K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cancer Running Title : MEK and Akt pathway radiosensitization in pancreatic cancer

B. Ross, A. Rehemtulla, T. Lawrence, 2012 .

Structural basis for L27 domain‐mediated assembly of signaling and cell polarity complexes

A. Lavie, B. Margolis, B. Demeler, 2004, The EMBO journal.

No small matter: microRNAs - key regulators of cancer stem cells.

Liang Xu, Rong-quan Wang, D. Karnak, 2010, International journal of clinical and experimental medicine.

Medical Hypothesis No small matter: microRNAs -- key regulators of cancer stem cells

Liang Xu, Rong-quan Wang, D. Karnak, 2010 .

DNA-PK inhibition and radiation promote anti-tumoral immunity through RNA Polymerase III in pancreatic cancer.

T. Lawrence, Qiang Zhang, T. Frankel, 2022, Molecular cancer research : MCR.

The potential for mid-treatment albumin-bilirubin (ALBI) score to individualize liver stereotactic body radiation therapy.

W. Jackson, M. Schipper, C. Mayo, 2021, International journal of radiation oncology, biology, physics.

HAb18G/CD147 Promotes pSTAT3-Mediated Pancreatic Cancer Development via CD44s

T. Lawrence, Jiayuh Lin, Liang Xu, 2013, Clinical Cancer Research.

Combined Inhibition of Wee1 and PARP1/2 for Radiosensitization in Pancreatic Cancer

T. Lawrence, J. Maybaum, Mary A Davis, 2014, Clinical Cancer Research.