D. Barefield

发表

The genetic landscape of cardiomyopathy and its role in heart failure.

E. McNally, D. Barefield, M. Puckelwartz, 2015, Cell metabolism.

Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury.

Erik N. Taylor, D. Kass, R. Gilbert, 2019, Journal of molecular and cellular cardiology.

A sensitive and specific quantitation method for determination of serum cardiac myosin binding protein-C by electrochemiluminescence immunoassay.

S. Sadayappan, D. Kuster, D. Barefield, 2013, Journal of visualized experiments : JoVE.

Experimental Modeling Supports a Role for MyBP-HL as a Novel Myofilament Component in Arrhythmia and Dilated Cardiomyopathy

Lorenzo L. Pesce, E. A. Waters, Andy H. Vo, 2017, Circulation.

Deletion of Sulfonylurea Receptor 2 in the Adult Myocardium Enhances Cardiac Glucose Uptake and Is Cardioprotective

A. E. Rossi, J. Makielski, E. McNally, 2019, JACC. Basic to translational science.

Partial and complete loss of myosin binding protein H-like cause cardiac conduction defects.

G. Fishman, M. Broman, E. McNally, 2022, Journal of molecular and cellular cardiology.

Contractile dysfunction in a mouse model expressing a heterozygous MYBPC3 mutation associated with hypertrophic cardiomyopathy.

P. D. de Tombe, S. Sadayappan, Mohit Kumar, 2014, American journal of physiology. Heart and circulatory physiology.

Phosphorylation of cMyBP-C affects contractile mechanisms in a site-specific manner.

S. Sadayappan, X. Ji, D. Barefield, 2014, Biophysical journal.

IL 10 Treatment Attenuates Pressure Overload-Induced Hypertrophic Remodeling and Improves Heart Function via STAT3 Dependent Inhibition of NF B Running title: Verma et al.; IL10 inhibits adverse cardiac remodeling in mice

A. Ghosh, R. Kishore, G. Qin, 2012 .

Interleukin-10 Treatment Attenuates Pressure Overload–Induced Hypertrophic Remodeling and Improves Heart Function via Signal Transducers and Activators of Transcription 3–Dependent Inhibition of Nuclear Factor-&kgr;B

A. Ghosh, R. Kishore, G. Qin, 2012, Circulation.

Altered C10 domain in cardiac myosin binding protein-C results in hypertrophic cardiomyopathy.

Michael J. Zilliox, M. Zilliox, S. Sadayappan, 2019, Cardiovascular research.

Enhanced Muscular Dystrophy from Loss of Dysferlin Is Accompanied by Impaired Annexin A6 Translocation after Sarcolemmal Disruption.

E. McNally, James L. Warner, J. Earley, 2016, The American journal of pathology.

Anti-latent TGFβ binding protein 4 antibody improves muscle function and reduces muscle fibrosis in muscular dystrophy

Carl Morris, E. McNally, L. Wood, 2021, Science Translational Medicine.

Transgenic overexpression of the SUR2A-55 splice variant in mouse heart reduces infract size and promotes protective mitochondrial function

J. Makielski, T. Hacker, E. McNally, 2018, Heliyon.

An actin-dependent annexin complex mediates plasma membrane repair in muscle

E. McNally, M. Quattrocelli, A. Demonbreun, 2016, The Journal of cell biology.

Highlights from the American Heart Association's Basic Cardiovascular Science 2018 Scientific Sessions

D. Barefield, Joanne F. Garbincius, 2018, Journal of the American Heart Association.

Distinct pathological signatures in human cellular models of myotonic dystrophy subtypes.

Janel L. Davis, Andy H. Vo, Hao F. Zhang, 2019, JCI insight.

Altered Enhancer and Promoter Usage Leads to Differential Gene Expression in the Normal and Failed Human Heart

M. Nóbrega, E. McNally, D. Barefield, 2020, Circulation. Heart failure.

Enhancer and promoter usage in the normal and failed human heart

M. Nóbrega, E. McNally, D. Barefield, 2020, bioRxiv.

Phosphorylation and function of cardiac myosin binding protein-C in health and disease.

S. Sadayappan, D. Barefield, 2010, Journal of molecular and cellular cardiology.

Haploinsufficiency of Cardiac Myosin Binding Protein-C in the Development of Hypertrophic Cardiomyopathy

D. Barefield, 2014 .

Loss of dysferlin or myoferlin results in differential defects in excitation–contraction coupling in mouse skeletal muscle

E. McNally, A. Demonbreun, D. Barefield, 2021, Scientific Reports.

A Critical Function for Ser-282 in Cardiac Myosin Binding Protein-C Phosphorylation and Cardiac Function

D. Bers, J. Molkentin, J. Lorenz, 2011, Circulation research.

Oxidative Stress in Dilated Cardiomyopathy Caused by MYBPC3 Mutation

C. D. dos Remedios, S. Sadayappan, M. Michels, 2015, Oxidative medicine and cellular longevity.

Sham Surgery and Inter-Individual Heterogeneity Are Major Determinants of Monocyte Subset Kinetics in a Mouse Model of Myocardial Infarction

C. Hamm, S. Sadayappan, T. Braun, 2014, PloS one.

A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping

E. McNally, M. Quattrocelli, M. Hadhazy, 2019, Disease Models & Mechanisms.

Recombinant annexin A6 promotes membrane repair and protects against muscle injury.

E. McNally, M. Quattrocelli, James L. Warner, 2019, The Journal of clinical investigation.

Intermittent glucocorticoid steroid dosing enhances muscle repair without eliciting muscle atrophy

Andy H. Vo, E. McNally, M. Quattrocelli, 2017, The Journal of clinical investigation.

Reengineering a transmembrane protein to treat muscular dystrophy using exon skipping.

C. Bönnemann, J. Goldstein, Matthew J. Wolf, 2015, The Journal of clinical investigation.

Peritoneal dialysis solutions reverse the hemodynamic effects of nitric oxide synthesis inhibitors.

S. Ram, D. Barefield, J. Work, 1995, Kidney international.

The naked mole-rat exhibits an unusual cardiac myofilament protein profile providing new insights into heart function of this naturally subterranean rodent

S. Weintraub, P. D. de Tombe, S. Sadayappan, 2017, Pflügers Archiv - European Journal of Physiology.

High-Throughput Diagnostic Assay for a Highly Prevalent Cardiomyopathy-Associated MYBPC3 Variant

S. Sadayappan, Thomas L Lynch, D. Barefield, 2016, Journal of molecular biomarkers & diagnosis.

Alterations in Multi‐Scale Cardiac Architecture in Association With Phosphorylation of Myosin Binding Protein‐C

Erik N. Taylor, R. Gilbert, S. Sadayappan, 2016, Journal of the American Heart Association.

Intermittent glucocorticoid treatment enhances skeletal muscle performance through sexually dimorphic mechanisms

E. McNally, M. Quattrocelli, M. Hadhazy, 2022, The Journal of clinical investigation.

Is haploinsufficiency a sufficient mechanism for MYBPC3 truncating mutations?

D. Barefield, 2023, The Journal of general physiology.

Haploinsufficiency of MYBPC3 exacerbates the development of hypertrophic cardiomyopathy in heterozygous mice.

J. Seidman, C. Seidman, J. Gorham, 2015, Journal of molecular and cellular cardiology.

Mechanisms of Sarcomere Protein Mutation-Induced Cardiomyopathies

D. Barefield, A. Álvarez-Arce, Kelly N Araujo, 2023, Current Cardiology Reports.

Cardiac myosin binding protein-C is a potential diagnostic biomarker for myocardial infarction.

P. Luther, Jody L. Martin, S. Sadayappan, 2012, Journal of molecular and cellular cardiology.

The naked mole-rat exhibits an unusual cardiac myofilament protein profile providing new insights into heart function of this naturally subterranean rodent

P. D. de Tombe, S. Sadayappan, R. Buffenstein, 2017, Pflügers Archiv: European Journal of Physiology.

A Critical Function for Ser-282 in Cardiac Myosin Binding Protein-C Phosphorylation and Cardiac Function

D. Bers, J. Molkentin, J. Lorenz, 2011, Circulation research.

Reengineering a transmembrane protein to treat muscular dystrophy using exon skipping.

C. Bönnemann, J. Goldstein, Matthew J. Wolf, 2015, The Journal of clinical investigation.

Distinct pathological signatures in human cellular models of myotonic dystrophy subtypes.

Janel L. Davis, Andy H. Vo, Hao F. Zhang, 2019, JCI insight.

Reduction of Filamin C Results in Altered Proteostasis, Cardiomyopathy, and Arrhythmias

L. Choudhury, Alfred L. George, Joyce C. Ohiri, 2024, Journal of the American Heart Association.

The effects of conditional loss of myosin binding protein H-like on cardiac function

D. Barefield, Hope V Burnham, Alexandra Pena, 2024, bioRxiv.