Q. Chang

发表

Digenic inheritance of non-syndromic deafness caused by mutations at the gap junction proteins Cx26 and Cx31

X. Liu, Shoeb Ahmad, D. Yan, 2008, Human Genetics.

Diverse deafness mechanisms of connexin mutations revealed by studies using in vitro approaches and mouse models

Shoeb Ahmad, Wenxue Tang, Xi Lin, 2009, Brain Research.

Differences in the Pathogenicity of the p.H723R Mutation of the Common Deafness-Associated SLC26A4 Gene in Humans and Mice

J. Wong, Shu-Wha Lin, I. Yu, 2013, PloS one.

Protection of Spiral Ganglion Neurons from Degeneration Using Small-Molecule TrkB Receptor Agonists

K. Ye, Xia Liu, S. Gong, 2013, The Journal of Neuroscience.

Gap Junction Mediated Intercellular Metabolite Transfer in the Cochlea Is Compromised in Connexin30 Null Mice

Shoeb Ahmad, Wenxue Tang, Xi Lin, 2008, PloS one.

Targeted connexin26 ablation arrests postnatal development of the organ of Corti.

Wenxue Tang, Xi Lin, Q. Chang, 2009, Biochemical and biophysical research communications.

Functional Studies Reveal New Mechanisms for Deafness Caused by Connexin Mutations

Shoeb Ahmad, Wenxue Tang, Xi Lin, 2009, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.

Connexin29 Is Highly Expressed in Cochlear Schwann Cells, and It Is Required for the Normal Development and Function of the Auditory Nerve of Mice

D. Paul, Yanping Zhang, Wenxue Tang, 2006, The Journal of Neuroscience.

Early postnatal virus inoculation into the scala media achieved extensive expression of exogenous green fluorescent protein in the inner ear and preserved auditory brainstem response thresholds

Shoeb Ahmad, Xi Lin, Q. Chang, 2013, The journal of gene medicine.

Restoration of connexin26 protein level in the cochlea completely rescues hearing in a mouse model of human connexin30-linked deafness

K. Willecke, Shoeb Ahmad, G. Söhl, 2007, Proceedings of the National Academy of Sciences.

Adaptor protein-3 complex is required for Vangl2 trafficking and planar cell polarity of the inner ear

Ping Chen, V. Faundez, Hao Wu, 2019, Molecular biology of the cell.

Functional Evaluation of GJB 2 Variants in Nonsyndromic Hearing Loss

C. Jeon, J. Bok, U. Kim, 2011 .

Virally-expressed connexin26 restores gap junction function in the cochlea of conditional Gjb2 knockout mice

Jianjun Wang, Xi Lin, Q. Chang, 2013, Gene Therapy.

Early developmental expression of connexin26 in the cochlea contributes to its dominate functional role in the cochlear gap junctions.

Shoeb Ahmad, Xiaoming Li, Wenxue Tang, 2012, Biochemical and biophysical research communications.

Connexin30 null and conditional connexin26 null mice display distinct pattern and time course of cellular degeneration in the cochlea

W. Kong, Wenxue Tang, Xi Lin, 2009, The Journal of comparative neurology.

Establishment of a Knock-In Mouse Model with the SLC26A4 c.919-2A>G Mutation and Characterization of Its Pathology

Xi Lin, Chen-Chi Wu, Jau-Min Wong, 2011, PloS one.

Virally mediated Kcnq1 gene replacement therapy in the immature scala media restores hearing in a mouse model of human Jervell and Lange-Nielsen deafness syndrome

Jianjun Wang, Xi Lin, Q. Chang, 2015, EMBO molecular medicine.

De novo mutation in ATP6V1B2 impairs lysosome acidification and causes dominant deafness-onychodystrophy syndrome

Weiwei Guo, Ping Chen, Hui Jiang, 2014, Cell Research.

A Novel Mechanism for Connexin 26 Mutation Linked Deafness: Cell Death Caused by Leaky Gap Junction Hemichannels

Xi Lin, Shoeb Ahmad, Shoeb Ahmad, 2006, The Laryngoscope.

Characterization of ATPase Activity of P2RX2 Cation Channel

X. Liu, Yanbin Zhang, F. Yuan, 2016, Front. Physiol..

Atoh1 Directs the Formation of Sensory Mosaics and Induces Cell Proliferation in the Postnatal Mammalian Cochlea In Vivo

Michael C. Kelly, Xi Lin, Q. Chang, 2012, The Journal of Neuroscience.

Functional Evaluation of GJB2 Variants in Nonsyndromic Hearing Loss

Xi Lin, Hong-Joon Park, Un-Kyung Kim, 2011, Molecular medicine.

Different functional consequences of two missense mutations in the GJB2 gene associated with non‐syndromic hearing loss

Xi Lin, Sang Heun Lee, Hong-Joon Park, 2009, Human mutation.

7,8,3'-Trihydroxyflavone, a potent small molecule TrkB receptor agonist, protects spiral ganglion neurons from degeneration both in vitro and in vivo.

K. Ye, Xia Liu, S. Gong, 2012, Biochemical and biophysical research communications.

Timed conditional null of connexin26 in mice reveals temporary requirements of connexin26 in key cochlear developmental events before the onset of hearing

Wenxue Tang, Xi Lin, Q. Chang, 2015, Neurobiology of Disease.

Molecular Atoh 1 Directs the Formation of Sensory Mosaics and Induces Cell Proliferation in the Postnatal Mammalian Cochlea In Vivo

Michael C. Kelly, Q. Chang, Erick Lin, 2022 .

Diverse deafness mechanisms of connexin mutations revealed by studies using in vitro approaches and mouse models

Shoeb Ahmad, Wenxue Tang, Xi Lin, 2009, Brain Research.