Dimitrios Tzalis

发表

Tuning the electronic properties of phenanthroline ligands: 3,8-bis(arylethynyl)-1,10-phenanthrolines and their Ru(II) complexes

Y. Tor, Dimitrios Tzalis, 1995 .

The European Lead Factory: A Blueprint for Public–Private Partnerships in Early Drug Discovery

A. Karawajczyk, Dimitrios Tzalis, K. Orrling, 2017, Front. Med..

European Lead Factory

Adam Nelson, Gerhard Müller, Fabrizio Giordanetto, 2017 .

Toward self-assembling dendrimers: Metal complexation induces the assembly of hyperbranched structures

Y. Tor, Dimitrios Tzalis, 1996 .

Set-up and screening of a fragment library targeting the 14-3-3 protein interface.

C. Ottmann, I. Landrieu, T. Obsil, 2019, MedChemComm.

Simple one-step synthesis of 3-bromo- and 3,8-dibromo-1,10-phenanthroline: Fundamental building blocks in the design of metal chelates

Y. Tor, Dimitrios Tzalis, S. Siegel, 1995 .

The Organic Chemsitry of Coordination Compounds: Unprecedented Substitution Reactions of Functionalized Polypyridine Complexes

Y. Tor, Dimitrios Tzalis, 1997 .

A Versatile Strategy for the Synthesis of 4,5-Dihydroxy-2,3-Pentanedione (DPD) and Related Compounds as Potential Modulators of Bacterial Quorum Sensing

Simona Collina, Fabrizio Giordanetto, Dimitrios Tzalis, 2018, Molecules.

Cesium hydroxide catalyzed addition of alcohols and amine derivatives to alkynes and styrene

P. Knochel, Dimitrios Tzalis, Christopher Koradin, 1999 .

Expansion of chemical space for collaborative lead generation and drug discovery: the European Lead Factory Perspective.

Adam Nelson, Tuomo Kalliokoski, Gerhard Müller, 2015, Drug discovery today.

Cesium Hydroxide Catalyzed Addition of Alcohols and Amine Derivatives to Alkynes and Styrene.

P. Knochel, Dimitrios Tzalis, Christopher Koradin, 1999 .

Cesium Hydroxide: A Superior Base for the Catalytic Alkynylation of Aldehydes and Ketones and Catalytic Alkenylation of Nitriles.

P. Knochel, Dimitrios Tzalis, 1999, Angewandte Chemie.

Ru-Centered coordination complexes as a new phase transfer catalyst for alkylation of enolates and Michael additions

P. Knochel, Dimitrios Tzalis, 1999 .

Cesium Hydroxide: A Superior Base for the Catalytic Alkynylation of Aldehydes and Ketones and Catalytic Alkenylation of Nitriles.

P. Knochel, Dimitrios Tzalis, 1999, Angewandte Chemie.

Coordination compounds as building blocks: single-step synthesis of multi-ruthenium(II) complexes

Y. Tor, Dimitrios Tzalis, 1996 .

STEREOCHEMICALLY-DEFINED SUPRAMOLECULAR ARCHITECTURES : DIASTEREOMERICALLY-PURE MULTI-RUII COMPLEXES

Y. Tor, Dimitrios Tzalis, 1997 .

Coordination Compounds as Building Blocks: Single-Step Synthesis of Heteronuclear Multimetallic Complexes Containing RuII and OsII

Y. Tor, Dimitrios Tzalis, P. Connors, 1998 .

Clinical candidates modulating protein-protein interactions: The fragment-based experience.

C. Ottmann, Dimitrios Tzalis, Stanimira Hristeva, 2019, European journal of medicinal chemistry.

Identification, design, synthesis, and pharmacological activity of (4-ethyl-piperazin-1-yl)-phenylmethanone derivatives with neuroprotective properties against β-amyloid-induced toxicity

Alexander Piechot, V. Papadopoulos, Vassilios Papadopoulos, 2005, Neuropharmacology.

IMI European Lead Factory — democratizing access to high-throughput screening

Stuart P. McElroy, Philip S. Jones, H. V. van Vlijmen, 2021, Nature reviews. Drug discovery.

Fragment‐Based Stabilizers of Protein–Protein Interactions through Imine‐Based Tethering

C. Ottmann, T. Hoffmann, L. Brunsveld, 2020, Angewandte Chemie (International Ed. in English).

The European lead factory—an experiment in collaborative drug discovery

Fabrizio Giordanetto, Dimitrios Tzalis, Hugh Laverty, 2016, Journal of Medicines Development Sciences.

Interrogating dense ligand chemical space with a forward-synthetic library

P. Kolb, E. Pardon, J. Steyaert, 2019, Proceedings of the National Academy of Sciences.

Fragment‐Based Stabilizers of Protein–Protein Interactions through Imine‐Based Tethering

C. Ottmann, T. Hoffmann, L. Brunsveld, 2020, Angewandte Chemie.

A Versatile Strategy for the Synthesis of 4,5-Dihydroxy-2,3-Pentanedione (DPD) and Related Compounds as Potential Modulators of Bacterial Quorum Sensing

S. Collina, F. Giordanetto, Silvia Stotani, 2018, Molecules.

An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-κB—Utilizing a Reversible Covalent Tethering Approach

C. Ottmann, T. Hoffmann, L. Brunsveld, 2021, Journal of medicinal chemistry.

Fragment‐Based Stabilizers of Protein–Protein Interactions through Imine‐Based Tethering

C. Ottmann, P. Cossar, Dimitrios Tzalis, 2020, Angewandte Chemie.