George L. Sen

发表

DNMT1 Maintains Progenitor Function in Self-Renewing Somatic Tissue

Paul A. Khavari, Li-Li Zhu, Jason A. Reuter, 2010, Nature.

The parathyroid hormone family member TIP39 interacts with sarco/endoplasmic reticulum Ca2+‐ ATPase activity by influencing calcium homoeostasis

R. Gallo, S. Imafuku, George L. Sen, 2017, Experimental dermatology.

Enhanc(er)ing Skin Stem Cells.

George L. Sen, Ying Wang, 2016, Cell stem cell.

Single-cell transcriptomics of human-skin-equivalent organoids

Shuxiong Wang, George L. Sen, Scott X. Atwood, 2022, bioRxiv.

PTH/PTHrP and Vitamin D Control Antimicrobial Peptide Expression and Susceptibility to Bacterial Skin Infection

L. Deftos, R. Gallo, G. Sen, 2012, Science Translational Medicine.

Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies

H. Blau, G. Sen, George L. Sen, 2005, Nature Cell Biology.

Transcription Factor PAX6 (Paired Box 6) Controls Limbal Stem Cell Lineage in Development and Disease*

Kang Zhang, Xiang-Dong Fu, R. Maas, 2015, The Journal of Biological Chemistry.

A brief history of RNAi: the silence of the genes

Helen M Blau, George L Sen, George L. Sen, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Active tissue-specific DNA demethylation conferred by somatic cell nuclei in stable heterokaryons

H. Blau, J. Pomerantz, A. Palermo, 2007, Proceedings of the National Academy of Sciences.

Post-Transcriptional Mechanisms Regulating Epidermal Stem and Progenitor Cell Self-Renewal and Differentiation.

George L. Sen, Jingting Li, 2016, The Journal of investigative dermatology.

CDK12 is Necessary to Promote Epidermal Differentiation through Transcription Elongation

Yifang Chen, George L. Sen, M. Tiwari, 2021, bioRxiv.

Remembering one's identity: the epigenetic basis of stem cell fate decisions

George L. Sen, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Antimicrobial Peptide LL37 and MAVS Signaling Drive Interferon-β Production by Epidermal Keratinocytes during Skin Injury.

Yi Fritz, N. Ward, A. Johnston, 2016, Immunity.

ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation.

Z. Siprashvili, Dan E. Webster, K. Qu, 2012, Developmental cell.

DNA methylation and epigenetic control of cellular differentiation

J. Rinn, David Khavari, G. Sen, 2010, Cell cycle.

ELL facilitates RNA Polymerase II mediated transcription of human epidermal proliferation genes.

M. Tiwari, Yifang Chen, George L. Sen, 2020, The Journal of investigative dermatology.

KLF3 Mediates Epidermal Differentiation through the Epigenomic Writer CBP

Jackson Jones, M. Tiwari, Yifang Chen, 2020, iScience.

Restriction enzyme–generated siRNA (REGS) vectors and libraries

Helen M Blau, J. Myers, H. Blau, 2004, Nature Genetics.

mRNA translation is not a prerequisite for small interfering RNA-mediated mRNA cleavage.

Helen M Blau, H. Blau, G. Sen, 2005, Differentiation; research in biological diversity.

SNAI2 Controls the Undifferentiated State of Human Epidermal Progenitor Cells

Ying Wang, George L Sen, Kang Zhang, 2014, Stem cells.

Progenitor function in self-renewing human epidermis is maintained by the exosome.

Yifang Chen, George L. Sen, Devendra S. Mistry, 2012, Cell stem cell.

SPT6 promotes epidermal differentiation and blockade of an intestinal-like phenotype through control of transcriptional elongation

P. Tamayo, Soumita Das, P. Ghosh, 2021, Nature Communications.

Regulation of integrin and extracellular matrix genes by HNRNPL is necessary for epidermal renewal

M. Tiwari, Yifang Chen, George L. Sen, 2021, PLoS biology.

HNRNPK maintains epidermal progenitor function through transcription of proliferation genes and degrading differentiation promoting mRNAs

O. Harismendy, Jackson Jones, M. Tiwari, 2019, Nature Communications.

Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3.

Howard Y. Chang, Howard Y Chang, Dan E. Webster, 2008, Genes & development.

RAS-mediated suppression of PAR3 and its effects on SCC initiation and tissue architecture occur independently of hyperplasia

Jackson Jones, M. Tiwari, Yifang Chen, 2020, Journal of Cell Science.

Highly rapid and efficient conversion of human fibroblasts to keratinocyte like cells

Yifang Chen, George L. Sen, Devendra S. Mistry, 2013, The Journal of investigative dermatology.

Cellular toxicity of silicon carbide nanomaterials as a function of morphology.

Yuting Bai, J. Jokerst, Gong-yi Li, 2018, Biomaterials.

Cutaneous innate immune tolerance is mediated by epigenetic control of MAP2K3 by HDAC8/9

R. Gallo, Y. Sawada, T. Dokoshi, 2021, Science Immunology.

DDX6 Orchestrates Mammalian Progenitor Function through the mRNA Degradation and Translation Pathways.

J. Lykke-Andersen, Yifang Chen, George L. Sen, 2015, Molecular cell.

TEAD1 and TEAD3 play redundant roles in the regulation of human epidermal proliferation.

P. Tamayo, M. Tiwari, Yifang Chen, 2020, The Journal of investigative dermatology.

Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis.

George L. Sen, Jingting Li, 2015, Journal of visualized experiments : JoVE.

RACK1 Prevents the Premature Differentiation of Epidermal Progenitor Cells by Inhibiting IRF6 Expression.

M. Tiwari, Yifang Chen, George L. Sen, 2021, The Journal of investigative dermatology.

BRD4 is necessary for differentiation downstream of epidermal lineage determining transcription factors.

Jackson Jones, M. Tiwari, Yifang Chen, 2020, The Journal of investigative dermatology.

The Cohesin Complex Is Necessary for Epidermal Progenitor Cell Function through Maintenance of Self-Renewal Genes.

Maria Noutsou, Jackson Jones, Yifang Chen, 2017, Cell reports.

Genomic profiling of a human organotypic model of AEC syndrome reveals ZNF750 as an essential downstream target of mutant TP63.

Dan E. Webster, K. Qu, P. Khavari, 2012, American journal of human genetics.

Increasing the Efficacy of Stem Cell Therapy via Triple-Function Inorganic Nanoparticles.

J. Jokerst, V. Grassian, Taeho Kim, 2019, ACS nano.

SOX2 expression inhibits terminal epidermal differentiation

Yifang Chen, George L. Sen, 2015, Experimental dermatology.