Chang-cheng Zhang

发表

Saponins of Panax japonicus Confer Neuroprotection against Brain Aging through Mitochondrial Related Oxidative Stress and Autophagy in Rats

C. Yuan, Yaoyan Dun, Jing-zhi Wan, 2020 .

Chikusetsu saponin IVa attenuates isoprenaline-induced myocardial fibrosis in mice through activation autophagy mediated by AMPK/mTOR/ULK1 signaling.

Zhiyong Zhou, Chang-cheng Zhang, Chaoqi Liu, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Icariin Intervenes in Cardiac Inflammaging through Upregulation of SIRT6 Enzyme Activity and Inhibition of the NF-Kappa B Pathway

H. Fang, B. Kalionis, S. Xia, 2015, BioMed research international.

Chikusetsu saponin IVa ameliorates high fat diet-induced inflammation in adipose tissue of mice through inhibition of NLRP3 inflammasome activation and NF-κB signaling

Junjie Wang, C. Yuan, Yaoyan Dun, 2017, Oncotarget.

Protective effect of saponins extract from Panax japonicus on myocardial infarction: involvement of NF‐κB, Sirt1 and mitogen‐activated protein kinase signalling pathways and inhibition of inflammation

Zhiyong Zhou, Chang-cheng Zhang, D. Yuan, 2014, The Journal of pharmacy and pharmacology.

Chikusetsu saponin V attenuates H2O2-induced oxidative stress in human neuroblastoma SH-SY5Y cells through Sirt1/PGC-1α/Mn-SOD signaling pathways.

Q. Yuan, Yaoyan Dun, Jing-zhi Wan, 2016, Canadian journal of physiology and pharmacology.

Saponins from Panax japonicus attenuate age-related neuroinflammation via regulation of the mitogen-activated protein kinase and nuclear factor kappa B signaling pathways

Yuan-jian Yang, Yaoyan Dun, Jing-zhi Wan, 2017, Neural regeneration research.

Saponins from Panax japonicus ameliorate age-related renal fibrosis by inhibition of inflammation mediated by NF-κB and TGF-β1/Smad signaling and suppression of oxidative stress via activation of Nrf2-ARE signaling

C. Yuan, Chang-cheng Zhang, Chaoqi Liu, 2020, Journal of ginseng research.

Protective effects of saponins from Panax japonicus on neurons of the colon myenteric plexus in aging rats through reduction of α‐synuclein through endoplasmic reticulum stress

Yaoyan Dun, Chang-cheng Zhang, Yumin He, 2020, Geriatrics & gerontology international.

The preventive effect of total saponins from Panax japonicus on inflammation and insulin resistance in adipose tissue of mice induced by a high-fat diet

C. Yuan, Chang-cheng Zhang, Chaoqi Liu, 2021 .

Regulatory effects of saponins from Panax japonicus on colonic epithelial tight junctions in aging rats

Jing Chen, Yaoyan Dun, Zhiyong Zhou, 2016, Journal of ginseng research.

Chikusetsusaponin V attenuates lipopolysaccharide-induced liver injury in mice

Yaoyan Dun, Jing-zhi Wan, Zhiyong Zhou, 2016, Immunopharmacology and immunotoxicology.

Saponins from Panax japonicus attenuate cognitive impairment in ageing rats through regulating microglial polarisation and autophagy

Zhiyong Zhou, Chang-cheng Zhang, Yumin He, 2021, Pharmaceutical biology.

Icariin improves brain function decline in aging rats by enhancing neuronal autophagy through the AMPK/mTOR/ULK1 pathway

Zhiyong Zhou, Chang-cheng Zhang, Chaoqi Liu, 2021, Pharmaceutical biology.

Chikusetsusaponin V Inhibits LPS-Activated Inflammatory Responses via SIRT1/NF-κB Signaling Pathway in RAW264.7 Cells

Q. Yuan, Chang-cheng Zhang, Chaoqi Liu, 2018, Inflammation.

Relief Effects of Icariin on Inflammation-Induced Decrease of Tight Junctions in Intestinal Epithelial Cells

Yaoyan Dun, Chang-cheng Zhang, Haixia Zhao, 2022, Frontiers in Pharmacology.

Common markers of testicular Sertoli cells

Chang-cheng Zhang, Haixia Zhao, D. Yuan, 2021, Expert review of molecular diagnostics.

[Triterpene saponins in Panax japonicus and their ~(13)C-NMR spectroscopic characteristics].

San-jin Cai, Chang-cheng Zhang, Yumin He, 2019, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

Chlorogenic Acid Suppresses miR-155 and Ameliorates Ulcerative Colitis Through the NF-κB/NLRP3 inflammasome Pathway.

C. Yuan, Chang-cheng Zhang, Chaoqi Liu, 2020, Molecular nutrition & food research.

Protective effect of Wuzi Yanzong recipe on testicular dysfunction through inhibition of germ cell apoptosis in ageing rats via endoplasmic reticulum stress

C. Yuan, Yaoyan Dun, Zhiyong Zhou, 2018, Andrologia.

Icariin attenuates perfluorooctane sulfonate-induced testicular toxicity by alleviating Sertoli cell injury and downregulating the p38MAPK/MMP9 pathway.

Yaoyan Dun, Chang-cheng Zhang, Haixia Zhao, 2022, Food & function.

Icariin Improves Age-Related Testicular Dysfunction by Alleviating Sertoli Cell Injury via Upregulation of the ERα/Nrf2-Signaling Pathway

Yaoyan Dun, Chang-cheng Zhang, Chaoqi Liu, 2020, Frontiers in Pharmacology.

Perfluorooctanoic acid induces tight junction injury of Sertoli cells by blocking autophagic flux.

Chang-cheng Zhang, Haixia Zhao, D. Yuan, 2023, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[Decline of secretory function of TM4 Sertoli cells stimulated by D-galactose in mice and its mechanism].

Chang-cheng Zhang, Haixia Zhao, D. Yuan, 2018, Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology.

Saponins from Panax japonicus attenuate D‐galactose‐induced cognitive impairment through its anti‐oxidative and anti‐apoptotic effects in rats

Li Yang, Yaoyan Dun, Jing-zhi Wan, 2015, The Journal of pharmacy and pharmacology.

Chikusetsu Saponin V Attenuates MPP+-Induced Neurotoxicity in SH-SY5Y Cells via Regulation of Sirt1/Mn-SOD and GRP78/Caspase-12 Pathways

Yaoyan Dun, Jing-zhi Wan, Zhiyong Zhou, 2014, International journal of molecular sciences.

[Effect of total saponins from Panax japonicus on non-alcoholic steatohepatitis by regulating autophagy].

C. Yuan, Chang-cheng Zhang, Chaoqi Liu, 2021, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

MiRNA-194 Regulates Palmitic Acid-Induced Toll-Like Receptor 4 Inflammatory Responses in THP-1 Cells

Xiaohuan Zou, Chang-cheng Zhang, Chaoqi Liu, 2015, Nutrients.

Preventive effects of total saponins of Panax japonicus on fatty liver fibrosis in mice

Yaoyan Dun, Zhiyong Zhou, Chang-cheng Zhang, 2016, Archives of medical science : AMS.

Oleanolic acid rejuvenates testicular function through attenuating germ cell DNA damage and apoptosis via deactivation of NF‐κB, p53 and p38 signalling pathways

Yongjun Wang, Yaoyan Dun, Zhiyong Zhou, 2017, The Journal of pharmacy and pharmacology.

Distinct expression patterns of aging effects on the UPRER signaling pathway in rat colon and regulatory role of saponins from Panax japonicus.

Yaoyan Dun, Chang-cheng Zhang, Yumin He, 2019, International journal of clinical and experimental pathology.

[Studies on preparative technology and quantitative determination for extracts of total saponin in roof of Panax japonicus].

Chang-cheng Zhang, Yumin He, D. Yuan, 2008, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

Cardioprotective effects of saponins from Panax japonicus on acute myocardial ischemia against oxidative stress-triggered damage and cardiac cell death in rats.

Chang-cheng Zhang, Yumin He, D. Yuan, 2012, Journal of ethnopharmacology.

Chikusetsusaponin V inhibits inflammatory responses via NF-κB and MAPK signaling pathways in LPS-induced RAW 264.7 macrophages

Yaoyan Dun, Jing-zhi Wan, Zhiyong Zhou, 2014, Immunopharmacology and immunotoxicology.

Protective Effects of Total Flavonoids from Epimedium on the Male Mouse Reproductive System Against Cyclophosphamide‐Induced Oxidative Injury by Up‐Regulating the Expressions of SOD3 and GPX1

Chang-cheng Zhang, Yumin He, D. Yuan, 2014, Phytotherapy research : PTR.

[HPLC-ELSD fingerprint and chemical constituents of Rhizoma Panacis Japonici].

Chang-cheng Zhang, Yumin He, D. Yuan, 2010, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

MiR-155/GSK-3β mediates anti-inflammatory effect of Chikusetsusaponin IVa by inhibiting NF-κB signaling pathway in LPS-induced RAW264.7 cell

Q. Yuan, Chang-cheng Zhang, Chaoqi Liu, 2020, Scientific Reports.

Saponins from Panax japonicus alleviate HFD-induced impaired behaviors through inhibiting NLRP3 inflammasome to upregulate AMPA receptors

C. Yuan, Zhiyong Zhou, Chang-cheng Zhang, 2021, Neurochemistry International.

[Effect of saponins extracted from Panax japonicas on inhibiting myocardial fibrosis by TGF-β1/Smad3 signaling pathway in aging rats].

Zhiyong Zhou, Chang-cheng Zhang, D. Yuan, 2018, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

[Protective Effect of Total Saponins of Panax japonicus Against H2O2-Induced Oxidative Stress Damage].

Li Yang, Chang-cheng Zhang, D. Yuan, 2015, Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.

Panax notoginseng saponins attenuate neuroinflammation through TXNIP-mediated NLRP3 inflammasome activation in aging rats.

Qingqing Zhao, C. Yuan, Yaoyan Dun, 2020, Current pharmaceutical biotechnology.

Vaccine adjuvant ginsenoside Rg1 enhances immune responses against hepatitis B surface antigen in mice.

Q. Yuan, Yaoyan Dun, Zhiyong Zhou, 2016, Canadian journal of physiology and pharmacology.

Saponins of Panax japonicus attenuate neuronal apoptosis through oxidative stress-related pathways and autophagy in natural aging rats.

C. Yuan, Yaoyan Dun, Jing-zhi Wan, 2019, Current pharmaceutical biotechnology.

The dynamic changes of Nrf2 mediated oxidative stress, DNA damage and base excision repair in testis of rats during aging

Yaoyan Dun, Zhiyong Zhou, Chang-cheng Zhang, 2021, Experimental Gerontology.

Saturated Fatty Acids Promote Hepatocytic Senecence through Negative Regulation of miR-34a/Cyclin-dependent Kinase 6.

C. Yuan, Chang-cheng Zhang, Chaoqi Liu, 2020, Molecular nutrition & food research.

Draft Vaccine Adjuvant Ginsenosides Rg 1 Enhances Immune Responses against Hepatitis B Surface Antigen in Mice

Q. Yuan, Yaoyan Dun, Zhiyong Zhou, 2016 .

Changes of Wnt/β-catenin signalling, BMP2, and BMP4 in the jejunum during ageing in rats.

J. Chen, Yaoyan Dun, Chang-cheng Zhang, 2020, Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology.

Panax notoginseng saponins attenuate cardiomyocyte apoptosis through mitochondrial pathway in natural aging rats

Yaoyan Dun, Zhiyong Zhou, Chang-cheng Zhang, 2018, Phytotherapy research : PTR.

Activation of NLRP3-Caspase-1 pathway contributes to age-related impairments in cognitive function and synaptic plasticity

Yuan-jian Yang, Zhiyong Zhou, Chang-cheng Zhang, 2021, Neurochemistry International.

Wuzi Yanzong administration alleviates Sertoli cell injury by recovering AKT/mTOR-mediated autophagy and the mTORC1-mTROC2 balance in aging-induced testicular dysfunction.

Chang-cheng Zhang, Haixia Zhao, Yumin He, 2023, Journal of ethnopharmacology.

[Artesunate induces prostate cancer cell line PC-3 differentiation and cell cycle arrest].

Chang-cheng Zhang, D. Yuan, Xiao-fei Huang, 2008, Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.

Chikusetsusaponin V Inhibits LPS-Activated Inflammatory Responses via SIRT1/NF-κB Signaling Pathway in RAW264.7 Cells

Q. Yuan, Chang-cheng Zhang, Chaoqi Liu, 2018, Inflammation.

Decline in testicular function in ageing rats: Changes in the unfolded protein response and mitochondrial apoptotic pathway

Chang-cheng Zhang, Chaoqi Liu, Haixia Zhao, 2019, Experimental Gerontology.

Saponins from Panax japonicus improve neuronal mitochondrial injury of aging rats

Zhiyong Zhou, Chang-cheng Zhang, D. Yuan, 2023, Pharmaceutical biology.