Paul K. Spearing

发表

Conformationally constrained farnesoid X receptor (FXR) agonists: alternative replacements of the stilbene.

G. B. Wisely, Shawn P. Williams, D. Parks, 2011, Bioorganic & medicinal chemistry letters.

A new series of estrogen receptor modulators that display selectivity for estrogen receptor beta.

L. Moore, M. Lambert, G. B. Wisely, 2002, Journal of medicinal chemistry.

Identification of potent, nonabsorbable agonists of the calcium-sensing receptor for GI-specific administration.

S. Roller, S. M. Sparks, Grace Chen, 2017, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of a series of mGlu7 NAMs based on an ethyl-8-methoxy-4-(4-phenylpiperazin-1-yl)quinoline carboxylate core.

Anna L. Blobaum, C. Lindsley, P. Conn, 2020, Bioorganic & medicinal chemistry letters.

VU6010608, a Novel mGlu7 NAM from a Series of N-(2-(1H-1,2,4-Triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamides.

Anna L. Blobaum, C. Lindsley, P. Conn, 2017, ACS medicinal chemistry letters.

VU6010608, a Novel mGlu 7 NAM from a Series of N ‑ (2-(1 H ‑ 1,2,4-Triazol-1-yl)-5-(tri ﬂ uoromethoxy)phenyl)benzamides

Anna L. Blobaum, C. Lindsley, C. Niswender, 2017 .

Synthesis of (R,S)-Dioclein, a Bioactive Flavanone from the Root Bark of Diocleia grandiflora

G. Majetich, Paul K. Spearing, J. Bhattacharyya, 1997 .

Discovery of tertiary sulfonamides as potent liver X receptor antagonists.

Paul R Reid, Timothy M Willson, William J Zuercher, 2010, Journal of medicinal chemistry.

Syntheses of 3,7-Dimethyl-8-hydroxy-6-methoxyisochroman, the 3,7-Dimethyl-6-hydroxy-8-methoxy Isomer, and Their Ester and Ether Derivatives: Plant Growth Regulatory Activity

H. Cutler, G. Majetich, X. Tian, 1997 .

Dioclenol, a minor flavanonol from the root-bark of Dioclea grandiflora

G. Majetich, R. Almeida, Paul K. Spearing, 1997 .

FXR agonist activity of conformationally constrained analogs of GW 4064.

Shawn P. Williams, D. Parks, K. Madauss, 2009, Bioorganic & medicinal chemistry letters.

Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene.

Shawn P Williams, G. B. Wisely, Shawn P. Williams, 2011, Bioorganic & medicinal chemistry letters.

Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064.

Shawn P Williams, G. B. Wisely, Shawn P. Williams, 2008, Bioorganic & medicinal chemistry letters.

Discovery of a novel, CNS penetrant M4 PAM chemotype based on a 6-fluoro-4-(piperidin-1-yl)quinoline-3-carbonitrile core.

C. Lindsley, Hyekyung P. Cho, P. Conn, 2017, Bioorganic & medicinal chemistry letters.

Discovery of a Novel Class of Heteroaryl-Pyrrolidinones as Positive Allosteric Modulators of the Muscarinic Acetylcholine Receptor M1.

Anna L. Blobaum, O. Boutaud, C. Lindsley, 2021, Bioorganic & medicinal chemistry letters.