Suzanne J. F. Kaptein

发表

Reverse engineering synthetic antiviral amyloids

Frederic Rousseau, Rodrigo Gallardo, Guy Bormans, 2020, Nature Communications.

Drug development of an affinity enhanced, broadly neutralizing heavy chain-only antibody that restricts SARS-CoV-2 in rodents

P. Maes, N. Callewaert, B. Weynand, 2021, bioRxiv.

A Dengue type 2 reporter virus assay amenable to high-throughput screening.

J. Neyts, P. Leyssen, K. Dallmeier, 2020, Antiviral research.

A Derivate of the Antibiotic Doxorubicin Is a Selective Inhibitor of Dengue and Yellow Fever Virus Replication In Vitro

P. Herdewijn, A. Gamarnik, M. Froeyen, 2010, Antimicrobial Agents and Chemotherapy.

Favipiravir inhibits in vitro Usutu virus replication and delays disease progression in an infection model in mice.

J. Neyts, S. Kaptein, Sapna Sharma, 2018, Antiviral research.

Identification of a new dengue virus inhibitor that targets the viral NS4B protein and restricts genomic RNA replication.

J. Neyts, F. V. van Kuppeveld, A. Davidson, 2013, Antiviral research.

Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug.

Alicia M. Hanson, M. Bolognesi, M. Pezzullo, 2012, The Journal of antimicrobial chemotherapy.

Design, synthesis, optimization and antiviral activity of a class of hybrid dengue virus E protein inhibitors.

J. Neyts, P. Leyssen, B. N. Sinha, 2015, Bioorganic & medicinal chemistry letters.

The Rat Cytomegalovirus R33-Encoded G Protein-Coupled Receptor Signals in a Constitutive Fashion

R. Leurs, P. Casarosa, M. Smit, 2002, Journal of Virology.

Human stem cell-derived hepatocyte-like cells support Zika virus replication and provide a relevant model to assess the efficacy of potential antivirals

C. Verfaillie, J. Neyts, S. Kaptein, 2018, PloS one.

Broad Antiviral Activity of Carbohydrate-Binding Agents against the Four Serotypes of Dengue Virus in Monocyte-Derived Dendritic Cells

J. Neyts, J. Balzarini, D. Schols, 2011, PloS one.

Reaching beyond HIV/HCV: nelfinavir as a potential starting point for broad-spectrum protease inhibitors against dengue and chikungunya virus

L. Delang, J. Neyts, S. Bhakat, 2015 .

Discovery of Multitarget Antivirals Acting on Both the Dengue Virus NS5-NS3 Interaction and the Host Src/Fyn Kinases.

G. Rastelli, M. Radi, E. Crespan, 2015, Journal of medicinal chemistry.

In search of Flavivirus inhibitors part 2: tritylated, diphenylmethylated and other alkylated nucleoside analogues.

J. Rozenski, J. Neyts, A. Van Aerschot, 2014, European journal of medicinal chemistry.

3',5'Di-O-trityluridine inhibits in vitro flavivirus replication.

J. Neyts, A. Van Aerschot, B. Canard, 2013, Antiviral research.

An Analogue of the Antibiotic Teicoplanin Prevents Flavivirus Entry In Vitro

A. Gamarnik, M. Preobrazhenskaya, J. Neyts, 2012, PloS one.

A Viral Polymerase Inhibitor Reduces Zika Virus Replication in the Reproductive Organs of Male Mice

L. Delang, J. Neyts, E. Verbeken, 2019, International journal of molecular sciences.

The Viral Polymerase Inhibitor 7-Deaza-2’-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model

J. Neyts, E. Verbeken, R. E. Marques, 2016, bioRxiv.

Molecular Dynamic Study and Synthesis of 1H-benzo[d]imidazole-5-carboxamide Derivatives as Inhibitors for Yellow Fever and Zika Virus Replication

J. Neyts, S. Kaptein, R. Serya, 2020, Archives of Pharmaceutical Sciences Ain Shams University.

Scaffold Morphing Approach To Expand the Toolbox of Broad-Spectrum Antivirals Blocking Dengue/Zika Replication.

M. Radi, J. Neyts, G. Costantino, 2019, ACS medicinal chemistry letters.

HIV / HCV : nel fi navir as a potential starting point for broad-spectrum protease inhibitors against dengue and chikungunya virus †

L. Delang, J. Neyts, S. Bhakat, 2015 .

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine lacks activity

B. Weynand, Rachel J. Williams, B. Hens, 2020, Proceedings of the National Academy of Sciences.

Antibody-dependent enhancement of dengue virus infection is inhibited by SA-17, a doxorubicin derivative.

J. Neyts, J. Smit, S. Kaptein, 2013, Antiviral research.

Debio 025, a Cyclophilin Binding Molecule, Is Highly Efficient in Clearing Hepatitis C Virus (HCV) Replicon-Containing Cells When Used Alone or in Combination with Specifically Targeted Antiviral Therapy for HCV (STAT-C) Inhibitors

Jan Paeshuyse, Johan Neyts, J. Neyts, 2008, Antimicrobial Agents and Chemotherapy.

A derivate of the antibiotic doxorubicin inhibits dengue and yellow fever virus replication in vitro

A. Gamarnik, J. Neyts, E. Clercq, 2008 .

Aminopurine and aminoquinazoline scaffolds for development of potential dengue virus inhibitors.

J. Rozenski, A. Venkatesham, M. Froeyen, 2017, European journal of medicinal chemistry.

Synthetic strategy and antiviral evaluation of diamide containing heterocycles targeting dengue and yellow fever virus

J. Rozenski, A. Marchand, J. Neyts, 2016, European journal of medicinal chemistry.

Antiviral activity of carbohydrate-binding agents and the role of DC-SIGN in dengue virus infection.

J. Neyts, J. Balzarini, D. Schols, 2009, Virology.

Antiviral Treatment of Chronic Hepatitis B Virus (HBV) Infections

E. De Clercq, J. Neyts, S. Kaptein, 2010, Viruses.

Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains

O. Faye, L. Nguyen, R. Jarman, 2021, Nature Communications.