Kasper Harpsøe

发表

A Robust Force Field Based Method for Calculating Conformational Energies of Charged Drug-Like Molecules

Lars Olsen, Flemming Steen Jørgensen, Jacob Poehlsgaard, 2012, J. Chem. Inf. Model..

GPCRdb: an information system for G protein-coupled receptors

Bas Vroling, Gert Vriend, Alexander S. Hauser, 2015, Nucleic Acids Res..

GPCRdb in 2018: adding GPCR structure models and ligands

Alexander S. Hauser, David E. Gloriam, Andrzej J. Bojarski, 2017, Nucleic Acids Res..

Structural insight to mutation effects uncover a common allosteric site in class C GPCRs

David E. Gloriam, Hans Bräuner-Osborne, Kasper Harpsøe, 2016, Bioinform..

A novel virtual screening paradigm via unsupervised iterative alignment and COSMOsar3D descriptors

Paolo Tosco, Kasper Harpsøe, Thomas Balle, 2012 .

Pharmacological Characterization and Modeling of the Binding Sites of Novel 1,3-Bis(pyridinylethynyl)benzenes as Metabotropic Glutamate Receptor 5-Selective Negative Allosteric Modulators

Christina Mølck, David E. Gloriam, Hans Bräuner-Osborne, 2012, Molecular Pharmacology.

Integrating structural and mutagenesis data to elucidate GPCR ligand binding.

David E. Gloriam, Kasper Harpsøe, Vignir Isberg, 2016, Current opinion in pharmacology.

GPCRdb: an information system for G protein-coupled receptors

Bas Vroling, Gert Vriend, Alexander S. Hauser, 2016, Nucleic acids research.

mGluR5: Exploration of Orthosteric and Allosteric Ligand Binding Pockets and Their Applications to Drug Discovery

Christina Mølck, David E. Gloriam, Hans Bräuner-Osborne, 2014, Neurochemical Research.

5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology

David E. Gloriam, John D. McCorvy, Bryan L. Roth, 2018, Cell.

Complementary three-dimensional quantitative structure-activity relationship modeling of binding affinity and functional potency: a study on alpha4beta2 nicotinic ligands.

Tommy Liljefors, Paolo Tosco, Kasper Harpsøe, 2009, Journal of medicinal chemistry.

Selective Negative Allosteric Modulation Of Metabotropic Glutamate Receptors – A Structural Perspective of Ligands and Mutants

David E. Gloriam, Hans Bräuner-Osborne, Kasper Harpsøe, 2015, Scientific Reports.

Structure–Activity Relationships for Negative Allosteric mGluR5 Modulators

Christina Mølck, Hans Bräuner-Osborne, Kasper Harpsøe, 2012, ChemMedChem.

Intersubunit Bridge Formation Governs Agonist Efficacy at Nicotinic Acetylcholine α4β2 Receptors

Kasper Harpsøe, Thomas Balle, Dan Peters, 2011, The Journal of Biological Chemistry.