Tsung H. Lin

发表

Cell Cycle Progression following Naive T Cell Activation Is Independent of Jak3/Common γ-Chain Cytokine Signals1

L. Berg, K. Appell, Leslie J. Berg, 2009, The Journal of Immunology.

Erratum: Integrin-mediated activation of MEK and mitogen-activated protein kinase is independent of Ras (Journal of Biological Chemistry (1996) 271 (18122-18127))

C. Der, R. Juliano, Qiming Chen, 1996 .

Integrin-mediated Activation of MEK and Mitogen-activated Protein Kinase Is Independent of Ras*

C. Der, R. Juliano, Qiming Chen, 1996, The Journal of Biological Chemistry.

Integrin-mediated Tyrosine Phosphorylation and Cytokine Message Induction in Monocytic Cells

S. Haskill, J. Bolen, R. Juliano, 1995, The Journal of Biological Chemistry.

Successful screening of large encoded combinatorial libraries leading to the discovery of novel p38 MAP kinase inhibitors.

M. Webb, D. Diller, A. Metzger, 2006, Combinatorial chemistry & high throughput screening.

PF-06651600, a Dual JAK3/TEC Family Kinase Inhibitor.

R. Everley, J. Telliez, Liang Xue, 2019, ACS chemical biology.

Demonstration of In Vitro to In Vivo Translation of a TYK2 Inhibitor That Shows Cross Species Potency Differences

J. D. Clark, M. Hegen, M. Dowty, 2020, Scientific Reports.

Identification and characterization of small‐molecule inhibitors of Tie2 kinase

M. Webb, R. Wen, I. Henderson, 2008, FEBS letters.

Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition.

J. Bauman, J. D. Clark, M. Hegen, 2016, ACS chemical biology.

pSTAT3: a target biomarker to study the pharmacology of the anti-IL-21R antibody ATR-107 in human whole blood

J. Masferrer, John B. Cheng, Tsung H. Lin, 2013, Journal of Translational Medicine.

Janus kinase inhibitors for the treatment of rheumatoid arthritis demonstrate similar profiles of in vitro cytokine receptor inhibition

M. Hegen, J. Telliez, M. Dowty, 2019, Pharmacology research & perspectives.

Discovery of Tyrosine Kinase 2 (TYK2) Inhibitor (PF-06826647) for the Treatment of Autoimmune Diseases.

S. Wright, J. D. Clark, M. Hegen, 2020, Journal of medicinal chemistry.

Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases.

Mark J. Mitton-Fry, J. D. Clark, M. Hegen, 2018, Journal of medicinal chemistry.

Cell Cycle Progression following Naive T Cell Activation Is Independent of Jak3/Common -Chain Cytokine Signals

K. Appell, Tsung H. Lin, Min-Min Shi, 2009 .

-Chain Cytokine Signals g Activation Is Independent of Jak3/Common Cell Cycle Progression following Naive T Cell

L. Berg, K. Appell, Tsung H. Lin, 2009 .

Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation.

L. Berg, K. Appell, Tsung H. Lin, 2008, Immunity.

OP0147 Lack of Differentiation of Janus Kinase Inhibitors in Rheumatoid Arthritis Based on Janus Kinase Pharmacology and Clinically Meaningful Concentrations

J. Telliez, M. Dowty, J. Jussif, 2014 .

Design and optimization of a series of 4-(3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-2-amines: Dual inhibitors of TYK2 and JAK1.

J. D. Clark, M. Hegen, Betsy S. Pierce, 2020, Bioorganic & medicinal chemistry.

Cell Anchorage Permits Efficient Signal Transduction Between Ras and Its Downstream Kinases*

R. Juliano, A. Howe, Qiming Chen, 1997, The Journal of Biological Chemistry.