Kook Hwan Kim

发表

Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

Nobuyuki Itoh, Masaaki Komatsu, Kyu Yeon Hur, 2012, Nature Medicine.

Autophagy as a crosstalk mediator of metabolic organs in regulation of energy metabolism

Myung-Shik Lee, Kook Hwan Kim, 2014, Reviews in Endocrine and Metabolic Disorders.

A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes

H. Kwon, Jin-Hee Ahn, Myung-Shik Lee, 2018, Nature Communications.

Amyloidogenic peptide oligomer accumulation in autophagy-deficient β cells induces diabetes.

M. Komatsu, Sang-Man Jin, S. Kang, 2014, The Journal of clinical investigation.

GDF15 as a central mediator for integrated stress response and a promising therapeutic molecule for metabolic disorders and NASH.

Myung-Shik Lee, Kook Hwan Kim, 2020, Biochimica et biophysica acta. General subjects.

Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice

Y. Jo, Yong‐ho Lee, Myung-Shik Lee, 2018, Scientific Reports.

Pathogenesis of Nonalcoholic Steatohepatitis and Hormone-Based Therapeutic Approaches

Myung-Shik Lee, Kook Hwan Kim, 2018, Front. Endocrinol..

An autophagy enhancer ameliorates diabetes of human IAPP-transgenic mice through clearance of amyloidogenic oligomer

H. Kim, Ji‐Won Kim, K. Yoon, 2021, Nature communications.

Snail acetylation by autophagy‐derived acetyl‐coenzyme A promotes invasion and metastasis of KRAS‐LKB1 co‐mutated lung cancer cells

J. Minna, M. White, Hyun Seok Kim, 2022, Cancer communications.

Fibroblast growth factor 21 participates in adaptation to endoplasmic reticulum stress and attenuates obesity-induced hepatic metabolic stress

M. Konishi, N. Itoh, Myung-Shik Lee, 2015, Diabetologia.

Acute Exercise Induces FGF21 Expression in Mice and in Healthy Humans

Y. Min, Hun-Mo Yang, Myung-Shik Lee, 2013, PloS one.

Cell non-autonomous effect of hepatic growth differentiation factor 15 on the thyroid gland

Sheue-yann Cheng, Y. Jo, Myung-Shik Lee, 2022, Frontiers in Endocrinology.

Autophagy—a key player in cellular and body metabolism

Myung-Shik Lee, Kook Hwan Kim, 2014, Nature Reviews Endocrinology.

Phosphorylation of EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha) is indispensable for nuclear translocation of TFEB and TFE3 during ER stress

E. Jho, H. Yoshida, S. Back, 2023, Autophagy.

Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition

E. Kang, B. Cha, S. Bae, 2017, Autophagy.

Metformin-induced inhibition of the mitochondrial respiratory chain increases FGF21 expression via ATF4 activation.

K. Park, Myung-Shik Lee, H. Jung, 2013, Biochemical and biophysical research communications.

TFEB–GDF15 axis protects against obesity and insulin resistance as a lysosomal stress response

Myung-Shik Lee, Seungsoo Chung, Y. Jang, 2021, Nature Metabolism.

TFEB–GDF15 axis protects against obesity and insulin resistance as a lysosomal stress response

Jinyoung Kim, Myung-Shik Lee, H. Park, 2021, Nature Metabolism.

FGF21 as a Stress Hormone: The Roles of FGF21 in Stress Adaptation and the Treatment of Metabolic Diseases

Myung-Shik Lee, Kook Hwan Kim, 2014, Diabetes & metabolism journal.

FGF21 as a mediator of adaptive responses to stress and metabolic benefits of anti-diabetic drugs.

Myung-Shik Lee, Kook Hwan Kim, 2015, The Journal of endocrinology.

A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes

H. Kwon, Myung-Shik Lee, Hui-Yun Hwang, 2018, Nature Communications.

Age-dependent gait abnormalities in mice lacking the Rnf170 gene linked to human autosomal-dominant sensory ataxia.

Jeongjin Kim, Youngsoo Kim, Daesoo Kim, 2015, Human molecular genetics.