Paula Perkins

Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor.

Peter Ballard, Simon J Brown, Nathaniel G. Martin, 2014, Journal of medicinal chemistry.

Small molecule binding sites on the Ras:SOS complex can be exploited for inhibition of Ras activation.

Malcolm Anderson, Jason G Kettle, Alexander L Breeze, 2015, Journal of medicinal chemistry.