Christina Backes

发表

IMOTA: an interactive multi-omics tissue atlas for the analysis of human miRNA–target interactions

Christina Backes, Eckart Meese, Andreas Keller, 2017, Nucleic Acids Res..

BN++ - A Biological Information System

Christina Backes, Michael Kaufmann, Hans-Peter Lenhof, 2006, J. Integr. Bioinform..

A high‐resolution map of the human small non‐coding transcriptome

Christina Backes, Benjamin Meder, Eckart Meese, 2018, Bioinform..

Computation of significance scores of unweighted Gene Set Enrichment Analyses

Christina Backes, Andreas Keller, Hans-Peter Lenhof, 2007, BMC Bioinformatics.

Regulatory MicroRNA Networks: Complex Patterns of Target Pathways for Disease-related and Housekeeping MicroRNAs

Christina Backes, Eckart Meese, Andreas Keller, 2015, Genom. Proteom. Bioinform..

RegulatorTrail: a web service for the identification of key transcriptional regulators

Christina Backes, Eckart Meese, Marcel H. Schulz, 2017, Nucleic Acids Res..

GraBCas: a bioinformatics tool for score-based prediction of Caspase- and Granzyme B-cleavage sites in protein sequences

Christina Backes, Eckart Meese, Hans-Peter Lenhof, 2005, Nucleic Acids Res..

BusyBee Web: metagenomic data analysis by bootstrapped supervised binning and annotation

Christina Backes, Andreas Keller, Tobias Fehlmann, 2017, Nucleic Acids Res..

miRCarta: a central repository for collecting miRNA candidates

Christina Backes, Eckart Meese, Andreas Keller, 2017, Nucleic Acids Res..

Genome-wide MicroRNA Expression Profiles in COPD: Early Predictors for Cancer Development

Christina Backes, Eckart Meese, Andreas Keller, 2018, Genom. Proteom. Bioinform..

DynaVenn: web-based computation of the most significant overlap between ordered sets

Christina Backes, Andreas Keller, Tobias Fehlmann, 2019, BMC Bioinformatics.

A novel algorithm for detecting differentially regulated paths based on gene set enrichment analysis

Christina Backes, Eckart Meese, Andreas Keller, 2009, Bioinform..

miEAA: microRNA enrichment analysis and annotation

Christina Backes, Eckart Meese, Andreas Keller, 2016, Nucleic Acids Res..

NetworkTrail - a web service for identifying and visualizing deregulated subnetworks

Christina Backes, Andreas Keller, Michael Kaufmann, 2013, Bioinform..

A review of databases predicting the effects of SNPs in miRNA genes or miRNA-binding sites

Christina Backes, Andreas Keller, Shashwat Sahay, 2019, Briefings Bioinform..

Bioinformatics approaches for cancer research

Christina Backes, 2010 .

ClinOmicsTrailbc: a visual analytics tool for breast cancer treatment stratification

Christina Backes, Eckart Meese, Andreas Keller, 2019, Bioinform..

EDISON-WMW: Exact Dynamic Programing Solution of the Wilcoxon–Mann–Whitney Test

Christina Backes, Eckart Meese, Andreas Keller, 2016, Genom. Proteom. Bioinform..

What's the target: understanding two decades of in silico microRNA-target prediction

Christina Backes, Eckart Meese, Andreas Keller, 2019, Briefings Bioinform..

Machine Learning to Detect Alzheimer’s Disease from Circulating Non-coding RNAs

Christina Backes, Eckart Meese, Andreas Keller, 2019, Genom. Proteom. Bioinform..

Integrating Culture-based Antibiotic Resistance Profiles with Whole-genome Sequencing Data for 11,087 Clinical Isolates

Christina Backes, Eckart Meese, Andreas Keller, 2019, Genom. Proteom. Bioinform..

Whole miRNome-wide Differential Co-expression of MicroRNAs

Christina Backes, Benjamin Meder, Eckart Meese, 2012, Genom. Proteom. Bioinform..

BALL-SNPgp - from genetic variants toward computational diagnostics

Sabine C. Mueller, Christina Backes, Eckart Meese, 2016, Bioinform..

BNDB – The Biochemical Network Database

Christina Backes, Michael Kaufmann, Hans-Peter Lenhof, 2007, BMC Bioinformatics.

miRPathDB: a new dictionary on microRNAs and target pathways

Christina Backes, Eckart Meese, Andreas Keller, 2016, Nucleic Acids Res..

Multi-omics enrichment analysis using the GeneTrail2 web service

Christina Backes, Eckart Meese, Andreas Keller, 2016, Bioinform..

GeneTrail—advanced gene set enrichment analysis

Christina Backes, Eckart Meese, Andreas Keller, 2007, Nucleic Acids Res..

miEAA 2.0: integrating multi-species microRNA enrichment analysis and workflow management systems

Christina Backes, Eckart Meese, Andreas Keller, 2020, bioRxiv.

Comparing genome versus proteome-based identification of clinical bacterial isolates

Christina Backes, Howard Li, Andre Franke, 2016, Briefings Bioinform..

PLSDB: a resource of complete bacterial plasmids

Christina Backes, Andreas Keller, Tobias Fehlmann, 2018, Nucleic Acids Res..

miRTrail - a comprehensive webserver for analyzing gene and miRNA patterns to enhance the understanding of regulatory mechanisms in diseases

Christina Backes, Jan Haas, Hugo A. Katus, 2012, BMC Bioinformatics.

Transcriptome analysis by GeneTrail revealed regulation of functional categories in response to alterations of iron homeostasis in Arabidopsis thaliana

Christina Backes, Andreas Keller, Hans-Peter Lenhof, 2011, BMC Plant Biology.

Toward the blood-borne miRNome of human diseases

Christina Backes, Benjamin Meder, Eckart Meese, 2011, Nature Methods.

miRTargetLink—miRNAs, Genes and Interaction Networks

Christina Backes, Benjamin Meder, Eckart Meese, 2016, International journal of molecular sciences.

Complex humoral immune response against a benign tumor: frequent antibody response against specific antigens as diagnostic targets.

Christina Backes, Eckart Meese, Andreas Keller, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Influence of next-generation sequencing and storage conditions on miRNA patterns generated from PAXgene blood.

Sabine C. Mueller, Christina Backes, Benjamin Meder, 2015, Analytical chemistry.

miFRame: analysis and visualization of miRNA sequencing data in neurological disorders

Christina Backes, Benjamin Meder, Eckart Meese, 2015, Journal of Translational Medicine.

Treatment-independent miRNA signature in blood of wilms tumor patients

Christina Backes, Eckart Meese, Andreas Keller, 2012, BMC Genomics.

Towards Clinical Applications of Blood-Borne miRNA Signatures: The Influence of the Anticoagulant EDTA on miRNA Abundance

Christina Backes, Eckart Meese, Andreas Keller, 2015, PloS one.

BN++ – A Biological Information System

Christina Backes, Hans-Peter Lenhof, Oliver Kohlbacher, 2008, J. Integr. Bioinform..

MicroRNA in vitro diagnostics using immunoassay analyzers.

Christina Backes, Benjamin Meder, Eckart Meese, 2015, Clinical chemistry.

Evaluating the Use of Circulating MicroRNA Profiles for Lung Cancer Detection in Symptomatic Patients.

Christina Backes, Benjamin Meder, Eckart Meese, 2020, JAMA oncology.

miRNAs can be generally associated with human pathologies as exemplified for miR-144*

Sabine C. Mueller, Christina Backes, Benjamin Meder, 2014, BMC Medicine.

Differentially regulated miRNAs as prognostic biomarkers in the blood of primary CNS lymphoma patients.

Christina Backes, Eckart Meese, Andreas Keller, 2015, European journal of cancer.

Deep characterization of blood cell miRNomes by NGS

Christina Backes, Benjamin Meder, Eckart Meese, 2016, Cellular and Molecular Life Sciences.

Machine Learning to Detect Alzheimer’s Disease from Circulating Non-coding RNAs

Christina Backes, Eckart Meese, Andreas Keller, 2019, bioRxiv.

A novel whole-blood miRNA signature for a rapid diagnosis of pulmonary tuberculosis

Christina Backes, Eckart Meese, Andreas Keller, 2015, European Respiratory Journal.

Influence of the confounding factors age and sex on microRNA profiles from peripheral blood.

Christina Backes, Benjamin Meder, Eckart Meese, 2014, Clinical chemistry.

Combining miRNA and mRNA Expression Profiles in Wilms Tumor Subtypes

Christina Backes, Eckart Meese, Andreas Keller, 2016, International journal of molecular sciences.

Comprehensive analysis of microRNA profiles in multiple sclerosis including next-generation sequencing

Christina Backes, Benjamin Meder, Eckart Meese, 2014, Multiple sclerosis.

Immunogenicity of autoantigens

Christina Backes, Eckart Meese, Andreas Keller, 2011, BMC Genomics.

Comprehensive Analysis of Human Endogenous Retrovirus Group HERV-W Locus Transcription in Multiple Sclerosis Brain Lesions by High-Throughput Amplicon Sequencing

Christina Backes, Klemens Ruprecht, E. Meese, 2013, Journal of Virology.

A dictionary on microRNAs and their putative target pathways

Christina Backes, Eckart Meese, Andreas Keller, 2010, Nucleic acids research.

What makes a blood cell based miRNA expression pattern disease specific? - A miRNome analysis of blood cell subsets in lung cancer patients and healthy controls

Christina Backes, Eckart Meese, Andreas Keller, 2014, Oncotarget.

Blood Born miRNAs Signatures that Can Serve as Disease Specific Biomarkers Are Not Significantly Affected by Overall Fitness and Exercise

Christina Backes, Eckart Meese, Andreas Keller, 2014, PloS one.

An integer linear programming approach for finding deregulated subgraphs in regulatory networks

Christina Backes, Eckart Meese, Andreas Keller, 2011, Nucleic acids research.

Bias in High-Throughput Analysis of miRNAs and Implications for Biomarker Studies.

Christina Backes, Benjamin Meder, Eckart Meese, 2016, Analytical chemistry.

An estimate of the total number of true human miRNAs

Christina Backes, Eckart Meese, Andreas Keller, 2019, Nucleic acids research.

From Single Variants to Protein Cascades

Sabine C. Mueller, Christina Backes, Benjamin Meder, 2015, The Journal of Biological Chemistry.

The human miRNA repertoire of different blood compounds

Christina Backes, Benjamin Meder, Eckart Meese, 2014, BMC Genomics.

Longitudinal study on circulating miRNAs in patients after lung cancer resection

Christina Backes, Eckart Meese, Andreas Keller, 2015, Oncotarget.

High-throughput qRT-PCR validation of blood microRNAs in non-small cell lung cancer

Christina Backes, Eckart Meese, Andreas Keller, 2015, Oncotarget.

MicroRNA expression profiles in human testicular tissues of infertile men with different histopathologic patterns.

Christina Backes, Eckart Meese, Andreas Keller, 2014, Fertility and sterility.

New insights into the genetics of glioblastoma multiforme by familial exome sequencing

Sabine C. Mueller, Christina Backes, Hugo A. Katus, 2014, Oncotarget.

miRNAs and sports: tracking training status and potentially confounding diagnoses

Christina Backes, Benjamin Meder, Eckart Meese, 2016, Journal of Translational Medicine.

Integrative analysis of cancer‐related data using CAP

Christina Backes, Eckart Meese, Hans-Peter Lenhof, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

BALL-SNP: combining genetic and structural information to identify candidate non-synonymous single nucleotide polymorphisms

Sabine C. Mueller, Christina Backes, Benjamin Meder, 2015, Genome Medicine.