S Hirota

Deficiency of c-kit+ cells in patients with a myopathic form of chronic idiopathic intestinal pseudo-obstruction.

K Isozaki, S. Hirota, Y. Matsuzawa, 1997, The American journal of gastroenterology.

A loss-of-function mutation of c-kit results in depletion of mast cells and interstitial cells of Cajal, while its gain-of-function mutation results in their oncogenesis.

S. Hirota, T. Nishida, Y. Kitamura, 2001, Mutation research.