Steven A King

Development of a catalytic enantioselective conjugate addition of 1,3-dicarbonyl compounds to nitroalkenes for the synthesis of endothelin-A antagonist ABT-546. Scope, mechanism, and further application to the synthesis of the antidepressant rolipram.

S. King, D. Barnes, S. Wittenberger, 2002, Journal of the American Chemical Society.