James E Bear

Mechanistic models of PLC/PKC signaling implicate phosphatidic acid as a key amplifier of chemotactic gradient sensing

Timothy C Elston, Jason M Haugh, Jamie L Nosbisch, 2020, PLoS Comput. Biol..

Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins

Brian Kuhlman, James E Bear, Hayretin Yumerefendi, 2014, Proceedings of the National Academy of Sciences.

Light-induced nuclear export reveals rapid dynamics of epigenetic modifications

Brian Kuhlman, Brian D. Strahl, James E Bear, 2016, Nature chemical biology.

Negative Regulation of Fibroblast Motility by Ena/VASP Proteins

James E Bear, Jürgen Wehland, Frank B Gertler, 2000, Cell.

PEGylated PRINT nanoparticles: the impact of PEG density on protein binding, macrophage association, biodistribution, and pharmacokinetics.

James E Bear, Joseph M DeSimone, Kevin P Herlihy, 2012, Nano letters.

Tumor Cell-Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression.

Robert Langer, Michael J Cima, Douglas A Lauffenburger, 2016, Cancer discovery.

Correlating in Vitro and in Vivo Activities of Light-Inducible Dimers: A Cellular Optogenetics Guide.

Brian Kuhlman, James E Bear, Hayretin Yumerefendi, 2016, ACS synthetic biology.

Directed migration of mesenchymal cells: where signaling and the cytoskeleton meet.

Jason M Haugh, James E Bear, J. Haugh, 2014, Current opinion in cell biology.

A cell-based assay for aggregation inhibitors as therapeutics of polyglutamine-repeat disease and validation in Drosophila

James E Bear, Frank B Gertler, Katalin Illes, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Nanoparticle clearance is governed by Th1/Th2 immunity and strain background.

James E Bear, Mary E Napier, Jillian L Perry, 2013, The Journal of clinical investigation.