J. Patrick

发表

Rapid determination of enzyme activities of recombinant human cytochromes P450, human liver microsomes and hepatocytes

A. Ghosal, Xiaowen Lu, N. Hapangama, 2003, Biopharmaceutics & drug disposition.

Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia).

R. Iannucci, A. Ghosal, K. Alton, 2004, Drug metabolism and disposition: the biological fate of chemicals.

Disposition and pharmacokinetics of temozolomide in rat

P. Statkevich, V. Batra, J. Patrick, 2004, Xenobiotica; the fate of foreign compounds in biological systems.

Disposition of 14C-eptifibatide after intravenous administration to healthy men.

M. Cayen, M. Affrime, K. Alton, 1998, Clinical therapeutics.

Quantitative analysis of albuterol in human plasma by combined gas chromatography chemical ionization mass spectrometry.

J. Patrick, M. Powell, M. Weisberger, 1983, Biomedical mass spectrometry.

Comparative bioavailability and pharmacokinetics of three formulations of albuterol.

E. Radwanski, S. Symchowicz, J. Patrick, 1985, Journal of pharmaceutical sciences.

Disposition of loratadine in healthy volunteers

R. Clement, K. Alton, S. Chowdhury, 2007, Xenobiotica; the fate of foreign compounds in biological systems.

Uterine prostaglandin concentrations in sheep during late pregnancy and adrenocorticotropin-induced labor.

J. Challis, J. Patrick, C. A. Evans, 1981, Endocrinology.

Fetal and maternal estrogen concentrations throughout pregnancy in the sheep.

J. Challis, J. Patrick, 1981, Canadian journal of physiology and pharmacology.

Antihypertensive effect of dilevalol is directly related to dose and plasma concentrations.

M. Affrime, G. Perentesis, B. Given, 1989, The American journal of cardiology.

DIURNAL CHANGES IN MATERNAL PLASMA OESTRONE AND OESTRADIOL AT 30 TO 31, 34 TO 35 AND 38 TO 39 WEEKS GESTATIONAL AGE

B. Richardson, R. Natale, J. Patrick, 1980, British journal of obstetrics and gynaecology.

High-performance liquid chromatographic determination of N-[2(S)-(mercaptomethyl)-3-(2-methylphenyl)-1-oxopropyl]-L-methionine, the active plasma metabolite of a prodrug atriopeptidase inhibitor (SCH 42495), using a thiol selective (Au/Hg) amperometric detector.

K. Alton, J. Patrick, N. Alvarez, 1992, Journal of chromatography.

Influence of food on the absorption of albuterol Repetabs.

M. Affrime, J. Gambertoglio, S. Symchowicz, 1989, The Journal of allergy and clinical immunology.

Short in vitro half-life of thymopoietin32--36 pentapeptide in human plasma.

G. Goldstein, J. Patrick, M. Chasin, 2009, International journal of peptide and protein research.

Effect of Food on the Oral Bioavailability of Isosorbide‐5‐Mononitrate Administered as an Extended‐Release Tablet

Jerome J. Schentag, D. Kazierad, E. Radwanski, 1995, Journal of clinical pharmacology.

Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of posaconazole (Noxafil).

R. Iannucci, A. Ghosal, K. Alton, 2004, Drug metabolism and disposition: the biological fate of chemicals.

Identification of human UDP‐glucuronosyltransferase enzyme(s) responsible for the glucuronidation of 3‐hydroxydesloratadine

A. Ghosal, K. Alton, S. Chowdhury, 2004, Biopharmaceutics & drug disposition.

The peripartal endocrine system in sheep

J. Challis, J. Patrick, J. Glickman, 1979 .

Pharmacokinetics and pharmacodynamics of dilevalol

M. Bottorff, M. Affrime, R. Lalonde, 1989, Clinical pharmacology and therapeutics.

The fetal membranes as a possible source of progesterone in the amniotic and allantoic fluids of pregnant sheep.

J. Challis, J. Patrick, G. D. Carson, 1982, Endocrinology.

High-performance liquid chromatographic assay for hydrochlorothiazide in human urine.

K. Alton, J. Patrick, D. Desrivieres, 1986, Journal of chromatography.

The development of fetal adrenal function.

J. Challis, B. Mitchell, J. Patrick, 1981, Ciba Foundation symposium.

Steroids in the amniotic fluid of the rhesus monkey (Macaca mulatta).

J. Robinson, J. Challis, J. Patrick, 1977, The Journal of endocrinology.

High-performance liquid chromatographic assay for the antiprotozoal agent, tinidazole, in human plasma.

K. Alton, J. Patrick, 1979, Journal of Pharmacy and Science.

Disposition of the selective cholesterol absorption inhibitor ezetimibe in healthy male subjects.

R. Iannucci, M. Cayen, M. Affrime, 2002, Drug metabolism and disposition: the biological fate of chemicals.

Cortisol in amniotic fluid of rhesus monkeys.

J. Robinson, J. Challis, J. Patrick, 1976, The Journal of endocrinology.

Perinatal pulmonary hyperplasia due to laryngeal atresia.

J. Patrick, M. Silver, W. Thurston, 1988, Human pathology.

Biotransformation of norgestimate in women.

K. Alton, C. Shaw, J. Patrick, 1984, Contraception.

Pharmacokinetics of dilevalol in normotensive and hypertensive volunteers.

M. Affrime, G. Perentesis, J. Patrick, 1989, The American journal of cardiology.

Disposition of norgestimate in the presence and absence of ethinyl estradiol after oral administration to humans.

J. Patrick, H. Weintraub, L. Abrams, 1978, Journal of pharmaceutical sciences.

Biotransformation of bromperidol in rat, dog, and man.

F. Wong, C. Shaw, J. Patrick, 1983, Drug metabolism and disposition: the biological fate of chemicals.

Short-term fluctuations in the concentration of cortisol and progesterone in fetal plasma, maternal plasma, and amniotic and allantoic fluids from sheep during late pregnancy.

J. Challis, J. Patrick, E. Manchester, 1981, Canadian journal of physiology and pharmacology.

Urethral and urachal urine output to the amniotic and allantoic sacs in fetal sheep.

J. Patrick, J. Challis, M. Wlodek, 1988, Journal of developmental physiology.

High-performance liquid chromatographic method for the quantification of unbound evernimicin in human plasma ultrafiltrate.

K. Alton, J. Patrick, N. Kishnani, 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

The Plasma Concentration and LDL‐C Relationship in Patients Receiving Ezetimibe

D. Wexler, T. Kosoglou, P. Statkevich, 2001, Journal of clinical pharmacology.

Biotransformation of a 1,5-benzodiazepine, triflubazam, by man.

K. Alton, C. Shaw, J. Patrick, 1975, Drug metabolism and disposition: the biological fate of chemicals.

Pharmacologic, Metabolic, and Toxicologic Profile of Spirapril (SCH 33844), a New Angiotensin Converting Inhibitor

E. Sybertz, J. Patrick, T. Baum, 1987, Journal of Cardiovascular Pharmacology.

Fragmentation of N-oxides (deoxygenation) in atmospheric pressure ionization: investigation of the activation process.

J E Patrick, W. Tong, K. Alton, 2001, Rapid communications in mass spectrometry : RCM.

Pharmacodynamic interaction between the new selective cholesterol absorption inhibitor ezetimibe and simvastatin

D. Cutler, M. Affrime, I. Meyer, 2002 .

Pharmacodynamic interaction between the new selective cholesterol absorption inhibitor ezetimibe and simvastatin.

D. Cutler, M. Affrime, I. Meyer, 2000, British journal of clinical pharmacology.

Relation between diurnal changes in peripheral plasma progesterone, cortisol, and estriol in normal women at 30-31, 34-35, and 38-39 weeks of gestation.

J. Challis, J. Patrick, C. Sprague, 1983, Gynecologic and obstetric investigation.

Prostaglandins in the plasma and amniotic fluid of rhesus monkeys during pregnancy and after intra-uterine foetal death.

M. Mitchell, J. Robinson, J. Challis, 1976, The Journal of endocrinology.

Stepwise determination of multicompartment disposition and absorption parameters from extravascular concentration-time data. Application to mesoridazine, flurbiprofen, flunarizine, labetalol, and diazepam

Kamal K. Midha, J. Chris Sackellares, John G. Wagner, 1991, Journal of Pharmacokinetics and Biopharmaceutics.

High-performance liquid chromatographic assay for the anthelmintic agent mebendazole in human plasma.

K. Alton, J. Patrick, J. McGUIRE, 1979, Journal of pharmaceutical sciences.

Pharmacokinetics and Bioavailability of Dilevalol in Normotensive Volunteers

M. Affrime, G. Perentesis, S. Symchowicz, 1988, Journal of clinical pharmacology.

The disposition of [3H]cortisol after intra-amniotic administration to sheep late in pregnancy.

J. Challis, J. Patrick, S. Power, 1980, Journal of developmental physiology.

Secretion of Dilevalol in Breast Milk

J. Patrick, N. Nagabhushan, Melton B. Affrime, 1988, Journal of clinical pharmacology.

Multiple‐Dose Albuterol Kinetics

E. Radwanski, S. Symchowicz, J. Patrick, 1986, Journal of clinical pharmacology.

Effects of naloxone on the breathing, electrocortical, heart rate, glucose and cortisol responses to hypoxia in the sheep fetus.

J. Challis, S. Adamson, J. Patrick, 1984, Journal of developmental physiology.

Diurnal changes in the concentration of progesterone in the plasma of women at 34-35 weeks of gestation.

J. Challis, J. Patrick, J. Workewych, 1981, The Journal of endocrinology.

Pharmacokinetics of isosorbide-5-mononitrate after oral administration of an extended-release mononitrate formulation versus a standard dinitrate formulation.

E. Radwanski, M. Affrime, T. Kosoglou, 1995, Clinical therapeutics.

Activation of adrenal function in fetal sheep by the infusion of adrenocorticotropin to the fetus in utero.

J. Challis, B. Mitchell, J. Patrick, 1982, Biology of Reproduction.

Changes in the diurnal rhythms of plasma cortisol in women during the third trimester of pregnancy.

J. Challis, J. Patrick, 1983, Gynecologic and obstetric investigation.

Metabolism and excretion of loratadine in male and female mice, rats and monkeys

K. Alton, S. Chowdhury, R. Ramanathan, 2005, Xenobiotica; the fate of foreign compounds in biological systems.

The effects of indomethacin on uterine activity and prostaglandin (PG) concentrations during labor induced by administering ACTH to fetal sheep.

J. Challis, J. Patrick, T. Kennedy, 1982, Canadian journal of physiology and pharmacology.

In vitro metabolism of 10‐(3‐chlorophenyl)‐6,8,9,10‐tetrahydrobenzo[b][1,8]naphthyridin‐5(7H)‐one, a topical antipsoriatic agent. Use of precision‐cut rat, dog, monkey and human liver slices, and chemical synthesis of metabolites

K. Ng, A. McPhail, M. Cayen, 1998, Biopharmaceutics & drug disposition.

Disposition of desloratadine in healthy volunteers

R. Clement, K. Alton, S. Chowdhury, 2005, Xenobiotica; the fate of foreign compounds in biological systems.

In Vitro Uptake of SCH 27899 (Evernimicin) by Rat Alveolar Macrophages

J. Brieland, D. Loebenberg, M. Cayen, 2001, Antimicrobial Agents and Chemotherapy.

The production of prostaglandins and thromboxanes in the feto-placental unit and their effects on the developing fetus.

J. Challis, J. Patrick, 1980, Seminars in perinatology.

Comparative bioavailability of a lipophilic steroid.

J. Patrick, H. Weintraub, L. Abrams, 1978, Journal of pharmaceutical sciences.