Zhao-bing Gao

发表

(−)-Naringenin 4′,7-dimethyl Ether Isolated from Nardostachys jatamansi Relieves Pain through Inhibition of Multiple Channels

Jun-Li Yang, Xian-Hua Meng, Ruoxi Gu, 2022, Molecules.

Antiepileptic geissoschizine methyl ether is an inhibitor of multiple neuronal channels

Cheng-gang Huang, Xue-qin Chen, L. Zhan, 2020, Acta Pharmacologica Sinica.

Identification of 2-substituted pyrrolo[1,2-b]pyridazine derivatives as new PARP-1 inhibitors.

Yi Chen, Z. Miao, Jian Ding, 2020, Bioorganic & medicinal chemistry letters.

Discovery of HN37 as a Potent and Chemically Stable Antiepileptic Drug Candidate.

F. Nan, Haichao Xu, L. Zhan, 2021, Journal of medicinal chemistry.

Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates

Xi Cheng, Lei-ke Zhang, Yan Wu, 2021, Acta Pharmacologica Sinica.

Kv1.2 potassium channel inhibitors from Chukrasia tabularis.

J. Yue, Ping Li, Zhao-bing Gao, 2012, Organic & biomolecular chemistry.

Discovery of Novel Retigabine Derivatives as Potent KCNQ4 and KCNQ5 Channel Agonists with Improved Specificity.

Lei Wang, F. Nan, Zhao-bing Gao, 2018, ACS medicinal chemistry letters.

Discovery of aryl sulfonamide-selective Nav1.7 inhibitors with a highly hydrophobic ethanoanthracene core

M. Gu, F. Nan, Zhao-bing Gao, 2019, Acta Pharmacologica Sinica.

Development of Novel Alkoxyisoxazoles as Sigma-1 Receptor Antagonists with Antinociceptive Efficacy.

Hao Sun, Jie Tang, Fan Yang, 2016, Journal of medicinal chemistry.

Inhibition of excitatory synaptic transmission by trans-resveratrol in rat hippocampus

G. Hu, Xue-qin Chen, Zhao-bing Gao, 2006, Brain Research.

Discovery of a retigabine derivative that inhibits KCNQ2 potassium channels

F. Nan, Zhao-bing Gao, Fei Chen, 2013, Acta Pharmacologica Sinica.

The synthesis and antistaphylococcal activity of N-sulfonaminoethyloxime derivatives of dehydroabietic acid.

Cai-Guang Yang, Yang Yao, Hu Zhou, 2018, Bioorganic & medicinal chemistry letters.

Chlorahololides C-F : a new class of potent and selective potassium channel blockers from Chloranthus holostegius

G. Hu, J. Yue, Zhao-bing Gao, 2008 .

Chlorahololides A and B, two potent and selective blockers of the potassium channel isolated from Chloranthus holostegius.

G. Hu, J. Yue, S. Liao, 2007, Organic letters.

Two novel C18-diterpenoid alkaloids, sinomontadine with an unprecedented seven-membered ring A and chloride-containing sinomontanine N from Aconitum sinomontanum

Kaixian Chen, Zhao-bing Gao, Q. Jia, 2017 .

Chukrasones A and B: potential Kv1.2 potassium channel blockers with new skeletons from Chukrasia tabularis.

J. Yue, Ping Li, Zhao-bing Gao, 2012, Organic letters.

Chlorahololides C—F: A New Class of Potent and Selective Potassium Channel Blockers from Chloranthus holostegius.

G. Hu, J. Yue, Zhao-bing Gao, 2008 .

Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors.

Yi Chen, Jian Ding, Xiaoyan Chen, 2020, European journal of medicinal chemistry.

Enhancing inactivation rather than reducing activation of Nav1.7 channels by a clinically effective analgesic CNV1014802

Zhao-bing Gao, Yueming Zheng, Yong-Chun Yu, 2017, Acta Pharmacologica Sinica.

SCN8A epileptic encephalopathy mutations display a gain-of-function phenotype and divergent sensitivity to antiepileptic drugs

Haichao Xu, L. Zhan, Zhao-bing Gao, 2022, Acta Pharmacologica Sinica.

Comparison of the effects of DC031050, a class III antiarrhythmic agent, on hERG channel and three neuronal potassium channels

Hualiang Jiang, G. Hu, Haifeng Sun, 2012, Acta Pharmacologica Sinica.

Functional characterization and in vitro pharmacological rescue of KCNQ2 pore mutations associated with epileptic encephalopathy

Zhao-bing Gao, H. Yuan, Fuyun Tian, 2023, Acta Pharmacologica Sinica.

Inhibitory effects of lappaconitine on the neuronal isoforms of voltage-gated sodium channels

Zhao-bing Gao, Yueming Zheng, Yong-Chun Yu, 2018, Acta Pharmacologica Sinica.

Identification and Evaluation of Antiepileptic Activity of C21 Steroidal Glycosides from the Roots of Cynanchum wilfordii.

Zhao-bing Gao, Weimin Zhao, Jin-Long Li, 2016, Journal of natural products.

Activation of human ether-a-go-go related gene (hERG) potassium channels by small molecules

Joseph J. Babcock, Zhao-bing Gao, Pingzheng Zhou, 2011, Acta Pharmacologica Sinica.

Discovering potassium channel blockers from synthetic compound database by using structure-based virtual screening in conjunction with electrophysiological assay.

Weiliang Zhu, Yang Li, Suxin Zheng, 2007, Journal of medicinal chemistry.

Trans-resveratrol, a red wine ingredient, inhibits voltage-activated potassium currents in rat hippocampal neurons

G. Hu, Zhao-bing Gao, 2005, Brain Research.

Ion channels research in the post-genomic era

B. Attali, Zhao-bing Gao, 2016, Acta Pharmacologica Sinica.

The synthesis and antistaphylococcal activity of dehydroabietic acid derivatives: modifications at C12 and C7.

Cai-Guang Yang, Zhao-bing Gao, Teng Yang, 2017, European journal of medicinal chemistry.

Naphthylisoquinoline alkaloids, a new structural template inhibitor of Nav1.7 sodium channel

Sheng Yao, Yang Ye, Chunping Tang, 2023, Acta Pharmacologica Sinica.

Kv1.2 potassium channel inhibitors from Chukrasia tabularis.

J. Yue, Ping Li, Zhao-bing Gao, 2012, Organic & biomolecular chemistry.

Novel KCNQ2 channel activators discovered using fluorescence-based and automated patch-clamp-based high-throughput screening techniques

Jin-feng Yue, Guan-hua Qiao, Ni Liu, 2016, Acta Pharmacologica Sinica.

Inhibitory effects of lappaconitine on the neuronal isoforms of voltage-gated sodium channels

Zhao-bing Gao, Yueming Zheng, Yong-Chun Yu, 2018, Acta Pharmacologica Sinica.