Buddha Gurung

发表

Islet-Specific Prmt5 Excision Leads to Reduced Insulin Expression and Glucose Intolerance in Mice.

Zijie Feng, Jian Ma, X. Hua, 2020, The Journal of endocrinology.

SUMO modification of menin.

Zijie Feng, X. Hua, Buddha Gurung, 2013, American journal of cancer research.

Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome.

T. Curran, Zijie Feng, X. Hua, 2013, Cancer research.

Tumor Syndrome Menin Epigenetically Represses Hedgehog Signaling in MEN 1

T. Curran, Zijie Feng, X. Hua, 2013 .

Menin Directly Represses Gli1 Expression Independent of Canonical Hedgehog Signaling

Zijie Feng, X. Hua, Buddha Gurung, 2013, Molecular Cancer Research.

Chromatin , Gene , and RNA Regulation Menin Directly Represses Gli 1 Expression Independent of Canonical Hedgehog Signaling

Zijie Feng, X. Hua, Buddha Gurung, 2013 .

Menin/PRMT5/Hedgehog signaling: A Potential Target for the Treatment of MEN1 Tumors

X. Hua, Buddha Gurung, 2017 .

Menin/PRMT5/hedgehog signaling: a potential target for the treatment of multiple endocrine neoplasia type 1 tumors.

X. Hua, Buddha Gurung, 2013, Epigenomics.

"…epigenetic regulation of gene expression represents a key aspect of menin's function … and the modulation of its epigenetic targets holds considerable therapeutic potential, including in multiple endocrine neoplasia type 1 syndrome."

Buddha Gurung, 2013 .

The Iron-Sulfur Cluster of the Rieske Iron-Sulfur Protein Functions as a Proton-exiting Gate in the Cytochrome bc1 Complex*

D. Xia, Chang-an Yu, Buddha Gurung, 2005, Journal of Biological Chemistry.

Menin-mediated regulation of miRNA biogenesis uncovers the IRS2 pathway as a target for regulating pancreatic beta cells

X. Hua, Bryson W. Katona, Buddha Gurung, 2014, Oncoscience.

Development of Multi-Engineered iPSC-Derived CAR-NK Cells for the Treatment of B-Cell Malignancies

M. Wallet, J. Carton, M. Beqiri, 2021, Blood.

Bi-specific and Split CAR T Cells Targeting CD13 and TIM3 Eradicate Acute Myeloid Leukemia.

C. June, Zijie Feng, Jian Ma, 2020, Blood.

The same pocket in menin binds both MLL and JUND but has opposite effects on transcription

M. Lei, J. Merchant, X. Hua, 2012, Nature.

Menin Is Required for Optimal Processing of the MicroRNA let-7a*

X. Hua, Buddha Gurung, Abdul Bari Muhammad, 2014, The Journal of Biological Chemistry.

, Abdul Bari Muhammad and let-7 a of the MicroRNA Menin Is Required for Optimal Processing

X. Hua, Buddha Gurung, Abdul Bari Muhammad, 2014 .

An Epigenetic Pathway Regulates Sensitivity of Breast Cancer Cells to HER2 Inhibition via FOXO/c-Myc Axis.

C. Dang, X. Hua, J. Liao, 2015, Cancer cell.

PTCH 1 staining of pancreatic neuroendocrine tumor (PNET) samples from patients with and without multiple endocrine neoplasia (MEN-1) syndrome reveals a potential therapeutic target

D. Metz, V. Livolsi, X. Hua, 2015, Cancer biology & therapy.

Stigmatellin Induces Reduction of Iron-Sulfur Protein in the Oxidized Cytochrome bc1 Complex*

Chang-an Yu, Buddha Gurung, Linda P. C. Yu, 2008, Journal of Biological Chemistry.

Structure and function studies of the cytochrome bc1 complex

Buddha Gurung, 2007 .

Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase.

M. Herlyn, A. Rustgi, H. Nakagawa, 2010, Cancer cell.