P. T. Nguyen

发表

Structural basis for antiarrhythmic drug interactions with the human cardiac sodium channel

Kevin R. DeMarco, V. Yarov-Yarovoy, I. Vorobyov, 2018, Proceedings of the National Academy of Sciences.

Identification of a hinge residue controlling islet amyloid polypeptide self-assembly and cytotoxicity

S. Bourgault, P. T. Nguyen, Elizabeth Godin, 2019, The Journal of Biological Chemistry.

Role of Site-Specific Asparagine Deamidation in Islet Amyloid Polypeptide Amyloidogenesis: Key Contributions of Residues 14 and 21.

S. Bourgault, M. Sebastiao, P. T. Nguyen, 2017, Biochemistry.

Cell surface glycosaminoglycans exacerbate plasma membrane perturbation induced by the islet amyloid polypeptide

S. Bourgault, M. Sebastiao, P. T. Nguyen, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Site-Specific Alkylation of the Islet Amyloid Polypeptide Accelerates Self-Assembly and Potentiates Perturbation of Lipid Membranes.

M. Golizeh, S. Bourgault, L. Sleno, 2021, Biochemistry.

Molecular determinants of μ-conotoxin KIIIA interaction with the human voltage-gated sodium channel NaV1.7

V. Yarov-Yarovoy, B. Olivera, Ian H. Kimball, 2019, bioRxiv.

Cell-Penetrating Ability of Peptide Hormones: Key Role of Glycosaminoglycans Clustering

S. Bourgault, P. T. Nguyen, Armelle Tchoumi Neree, 2015, International journal of molecular sciences.

Low generation anionic dendrimers modulate islet amyloid polypeptide self-assembly and inhibit pancreatic β-cell toxicity

R. Roy, S. Bourgault, Rishi Sharma, 2016 .

Probing the role of λ6 immunoglobulin light chain dimerization in amyloid formation.

S. Bourgault, P. T. Nguyen, Noé Quittot, 2016, Biochimica et biophysica acta.

Delineating the Role of Helical Intermediates in Natively Unfolded Polypeptide Amyloid Assembly and Cytotoxicity.

S. Bourgault, P. T. Nguyen, Noé Quittot, 2015, Angewandte Chemie.

New insights into the roles of sulfated glycosaminoglycans in islet amyloid polypeptide amyloidogenesis and cytotoxicity.

S. Bourgault, P. T. Nguyen, Carole Anne De Carufel, 2013, Biopolymers.

Endogenous retrovirus-encoded Syncytin-2 contributes to exosome-mediated immunosuppression of T cells†

E. Rassart, A. Lokossou, A. Vargas, 2019, Biology of Reproduction.

Contribution of the 12–17 hydrophobic region of islet amyloid polypeptide in self-assembly and cytotoxicity

S. Bourgault, Vy Nguyen, P. T. Nguyen, 2022, Frontiers in Molecular Biosciences.

Secondary conformational conversion is involved in glycosaminoglycans‐mediated cellular uptake of the cationic cell‐penetrating peptide PACAP

S. Bourgault, A. Fournier, D. Chatenet, 2014, FEBS letters.

Key role of secondary conformational conversion in glycosaminoglycans-mediated cellular uptake of PACAP , a cationic cell-penetrating peptide

A. Fournier, D. Chatenet, P. T. Nguyen, 2014 .

Molecular Interactions of Tannic Acid with Proteins Associated with SARS-CoV-2 Infectivity

N. Mousseau, S. Bourgault, T. V. D. van de Ven, 2022, International journal of molecular sciences.

Cytotoxic flavonoids from the roots of Bougainvillea spectabilis

Y. Tran, P. T. Nguyen, Van-Kieu Nguyen, 2021 .

EWSR1, a multifunctional protein, regulates cellular function and aging via genetic and epigenetic pathways.

Sooyoung Chung, N. Kowall, H. Ryu, 2019, Biochimica et biophysica acta. Molecular basis of disease.

Genetic Ablation of EWS RNA Binding Protein 1 (EWSR1) Leads to Neuroanatomical Changes and Motor Dysfunction in Mice

Sooyoung Chung, H. Ryu, Junghee Lee, 2018, Experimental neurobiology.

Synthesis of Analogs of Trans-Fagaramide and Their Cytotoxic Activity

R. Roy, S. Bourgault, T. Shiao, 2018, Pharmaceutical Chemistry Journal.

HIV-1 Antisense Protein of Different Clades Induces Autophagy and Associates with the Autophagy Factor p62

E. Rassart, Zhenlong Liu, S. Cen, 2018, Journal of Virology.

Epigenetic crosstalk: Pharmacological inhibition of HDACs can rescue defective synaptic morphology and neurotransmission phenotypes associated with loss of the chromatin reader Kismet

Faith L. W. Liebl, Jennifer M. Viveiros, Faith L W Liebl, 2017, Molecular and Cellular Neuroscience.

α-Synuclein Preformed Fibrils Bind to β-Neurexins and Impair β-Neurexin-Mediated Presynaptic Organization

S. Bourgault, Hideto Takahashi, P. T. Nguyen, 2023, bioRxiv.

Corilagin and 1,3,6-Tri-O-galloy-β-D-glucose: potential inhibitors of SARS-CoV-2 variants.

N. Mousseau, S. Bourgault, Vincent Binette, 2021, Physical chemistry chemical physics : PCCP.

The Endoplasmic Reticulum and Its Contacts: Emerging Roles in Axon Development, Neurotransmission, and Degeneration.

V. Haucke, M. Kuijpers, P. T. Nguyen, 2023, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

Identification of transmissible proteotoxic oligomer-like fibrils that expand conformational diversity of amyloid assemblies

A. Arnold, S. Bourgault, I. Marcotte, 2021, Communications biology.

Adsorption of Tannic Acid onto Gold Surfaces.

S. Bourgault, T. V. D. van de Ven, P. T. Nguyen, 2023, Langmuir : the ACS journal of surfaces and colloids.

Truncated netrin-1 contributes to pathological vascular permeability in diabetic retinopathy.

T. Kennedy, S. Bourgault, F. Rezende, 2016, The Journal of clinical investigation.

Different arrhythmia-associated calmodulin mutations have distinct effects on cardiac SK channel regulation

Hannah A. Ledford, V. Yarov-Yarovoy, A. George, 2020, The Journal of general physiology.

Synthesis and characterization of tetraphenylethylene-functionalized N-heterocyclic carbene-stabilized gold nanoparticles with aggregation-induced emission

S. Bourgault, A. Nazemi, P. T. Nguyen, 2023, Canadian Journal of Chemistry.

Identification of a conformational heparin-recognition motif on the peptide hormone secretin: key role for cell surface binding.

M. Lussier, S. Bourgault, P. T. Nguyen, 2017, The Biochemical journal.

Mechanistic Contributions of Biological Cofactors in Islet Amyloid Polypeptide Amyloidogenesis

S. Bourgault, Nagore Andraka, P. T. Nguyen, 2015, Journal of diabetes research.

Synthetic Multicomponent Nanovaccines Based on the Molecular Co-assembly of β-Peptides Protect against Influenza A Virus.

S. Bourgault, D. Archambault, D. Giguère, 2023, ACS infectious diseases.

Gain-of-function mutation of a voltage-gated sodium channel NaV1.7 associated with peripheral pain and impaired limb development

S. Dib-Hajj, S. Waxman, V. Yarov-Yarovoy, 2017, The Journal of Biological Chemistry.

Converting the Amyloidogenic Islet Amyloid Polypeptide into a Potent Nonaggregating Peptide Ligand by Side Chain-to-Side Chain Macrocyclization.

S. Bourgault, P. T. Nguyen, M. Babych, 2024, Journal of the American Chemical Society.