J. Abbott

发表

Cooperative binding of the Escherichia coli repressor of biotin biosynthesis to the biotin operator sequence.

D. Beckett, J. Abbott, Jennifer Abbott, 1993, Biochemistry.

Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS.

S. Fesik, A. Waterson, O. Rossanese, 2018, ACS medicinal chemistry letters.

Stereoselective synthesis of the disaccharide unit of incednine.

W. Roush, J. Abbott, 2013, Organic letters.

Stereoselective synthesis of a model C(18)-C(35) spiroketal fragment of integramycin.

W. Roush, J. Abbott, Huikai Sun, 2011, Organic letters.

alpha-Conotoxins, small peptide probes of nicotinic acetylcholine receptors.

B. Olivera, W. Gray, L. Cruz, 1991, Biochemistry.

Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor

A. Waterson, D. Rudolph, M. Gmachl, 2022, Journal of medicinal chemistry.

Preparation of Crystalline (Diisopinocampheyl)borane

J. Abbott, 2015 .

Enantioselective Reductive Syn-Aldol Reactions of 4-Acryloylmorpholine: Preparation of (2R, 3S)-3-Hydroxy-2-methyl-1-morpholino-5-phenylpentan-1-one

W. Roush, C. Allais, J. Abbott, 2015 .

Amides as excellent mimics of phosphate linkages in RNA.

S. Kennedy, C. Selvam, E. Rozners, 2011, Angewandte Chemie.

Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS.

S. Fesik, A. Waterson, O. Rossanese, 2018, Journal of medicinal chemistry.

Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling.

S. Fesik, A. Waterson, O. Rossanese, 2018, Journal of medicinal chemistry.

High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling.

S. Fesik, A. Waterson, O. Rossanese, 2018, Analytical biochemistry.