R. Ward

发表

The Role of Plasmhogen Activators in the Regulation of Connective Tissue Metalloproteinases a

J. Reynolds, G. Murphy, S. Atkinson, 1992 .

Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP).

M. Cockett, G. Murphy, A. Docherty, 1991, The Biochemical journal.

Presenilins--in search of functionality.

D. Allsop, E. Karran, J. Davis, 1998, Biochemical Society transactions.

Gingival fibroblasts degrade type I collagen films when stimulated with tumor necrosis factor and interleukin 1: evidence that breakdown is mediated by metalloproteinases.

J. Reynolds, G. Murphy, S. Atkinson, 1989, Journal of periodontal research.

Intermolecular Autolytic Cleavage Can Contribute to the Activation of Progelatinase A by Cell Membranes (*)

M. Seiki, J. Reynolds, G. Murphy, 1995, The Journal of Biological Chemistry.

Regulation of Matrix Metalloproteinase Activity a

J. O'Connell, G. Murphy, F. Willenbrock, 1994, Annals of the New York Academy of Sciences.

Physiological mechanisms for metalloproteinase activation.

G. Murphy, S. Atkinson, J. Gavrilović, 1992, Matrix (Stuttgart, Germany). Supplement.

Proteolytic Fragments of Alzheimer’s Disease‐Associated Presenilin 1 Are Present in Synaptic Organelles and Growth Cone Membranes of Rat Brain

C. Masters, G. Multhaup, K. Beyreuther, 1999, Journal of neurochemistry.

Tissue inhibitor of metalloproteinases and collagenase inhibitory activity in lung secretions from patients with chronic obstructive bronchitis: effect of corticosteroid treatment.

R. Stockley, S. Afford, D. Burnett, 1986, Thorax.

The purification of tissue inhibitor of metalloproteinases-2 from its 72 kDa progelatinase complex. Demonstration of the biochemical similarities of tissue inhibitor of metalloproteinases-2 and tissue inhibitor of metalloproteinases-1.

R. Hembry, J. Reynolds, G. Murphy, 1991, The Biochemical journal.

Cell-mediated degradation of type IV collagen and gelatin films is dependent on the activation of matrix metalloproteinases.

J. Reynolds, G. Murphy, S. Atkinson, 1992, The Biochemical journal.

A fibrosarcoma model derived from mouse embryo cells: Growth properties and secretion of collagenase and metalloproteinase inhibitor (TIMP) by tumour cell lines

J. Reynolds, R. Ward, N. Hicks, 1984, International journal of cancer.

Interaction between Progelatinase A and TIMP‐2

K. Iwata, N. Fujimoto, R. Ward, 1994, Annals of the New York Academy of Sciences.

Expression, purification, and functional analysis of the human serine protease HtrA2.

E. Karran, O. Jenkins, C. Creasy, 2000, Protein expression and purification.

Common structural features determine the effectiveness of carvedilol, daunomycin and rolitetracycline as inhibitors of Alzheimer beta-amyloid fibril formation.

D. Owen, D. Howlett, R. Markwell, 1999, The Biochemical journal.

Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase.

K. Tryggvason, R. Hembry, J. Reynolds, 1989, The Biochemical journal.

Extracellular matrix and matrix metalloproteinases in sciatic nerve

D. Edwards, J. Gavrilović, C. A. Krekoski, 2003, Journal of neuroscience research.

Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response.

C. Southan, G. P. Livi, E. Karran, 2000, European journal of biochemistry.

The C-terminal domain of 72 kDa gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases.

M. Cockett, G. Murphy, G Murphy, 1992, The Biochemical journal.

Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of beta-amyloid peptide.

D. Owen, E. Karran, J. Hawkins, 2000, The Biochemical journal.

Cell surface-mediated activation of progelatinase A: demonstration of the involvement of the C-terminal domain of progelatinase A in cell surface binding and activation of progelatinase A by primary fibroblasts.

J. Reynolds, G. Murphy, S. Atkinson, 1994, The Biochemical journal.

Interaction between tissue inhibitor of metalloproteinases-2 and progelatinase A: immunoreactivity analyses.

K. Iwata, N. Fujimoto, K. Yamashita, 1996, The Biochemical journal.

Tissue inhibitor of metalloproteinases-2 inhibits the activation of 72 kDa progelatinase by fibroblast membranes.

P. Slocombe, J. Reynolds, G. Murphy, 1991, Biochimica et biophysica acta.

Presenilin-1 is processed into two major cleavage products in neuronal cell lines.

J. Hardy, M. Hutton, M. Caivano, 1996, Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration.

Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of beta-amyloid peptide.

D. Owen, E. Karran, J. Hawkins, 2000, The Biochemical journal.

Biological activity associated with a high molecular weight form of β-amyloid.

D. Allsop, E. Karran, K. H. Jennings, 1999 .