J. Mazaleyrat

发表

A cyclopeptidic suicide substrate preferentially inactivates urokinase-type plasminogen activator.

M. Reboud-Ravaux, N. Boggetto, A. Vilain, 1991, Biochemical and biophysical research communications.

Specific and irreversible cyclopeptide inhibitors of dipeptidyl peptidase IV activity of the T-cell activation antigen CD26.

J. Blanco, E. Jacotot, A. Hovanessian, 1998, Journal of medicinal chemistry.

Synthesis of a potential “suicide substrate” of the HIV-1 protease, incorporating A 3-acetoxy-Δ-4,5-(L)-pipecolic acid as proline substitute.

Juan Xie, J. Mazaleyrat, M. Wakselman, 1992 .

Synthesis and characterisation of helical beta-peptide architectures that contain (S)-beta3-HDOPA(Crown Ether) derivatives.

C. Toniolo, F. Formaggio, C. Peggion, 2008, Chemistry.

Synthesis of a potential “suicide substrate” of the HIV-1 protease, incorporating A 3-acetoxy-Δ-4,5-(L)-pipecolic acid as proline substitute.

Juan Xie, J. Mazaleyrat, M. Wakselman, 1992 .

Acyloxybenzyl halides, inhibitors of elastases.

V. Okochi, M. Reboud-Ravaux, A. Vilain, 1991, Biochimica et biophysica acta.

Urethane protected amino acid N-carboxyanhydrides and fluorides (U-NCAs and U2AAFs)

J. Mazaleyrat, M. Wakselman, J. Šavrda, 1994, Amino Acids.

Evidence for the 310‐helical structure of peptides based on antAib, a fluorophoric, anthracene‐fused, 1‐aminocyclopentane‐1‐carboxylic acid

C. Toniolo, F. Formaggio, K. Wright, 2007 .

Synthesis and conformational study of homo-peptides based on (S)-Bin, a C2-symmetric binaphthyl-derived Cα,α-disubstituted glycine with only axial chirality

C. Toniolo, F. Formaggio, S. Oancea, 2003 .

Synthesis and complexing properties of chiral macrocycles containing enforced cavities

R. Helgeson, D. Cram, J. Mazaleyrat, 1981 .

Synthesis, Ion Complexation Study, and 3D‐Structural Analysis of Peptides Based on Crown‐Carrier, Cα‐Methyl‐L‐DOPA Amino Acids

C. Toniolo, F. Formaggio, T. Keiderling, 2008 .

Dipeptidyl‐peptidase IV‐β

J. Blanco, E. Jacotot, A. Hovanessian, 1998 .

New mechanism-based inactivators of trypsin-like proteinases. Selective inactivation of urokinase by functionalized cyclopeptides incorporating a sulfoniomethyl-substituted m-aminobenzoic acid residue.

M. Reboud-Ravaux, N. Boggetto, A. Vilain, 1993, Journal of medicinal chemistry.

Susceptibility of plasminogen activators to suicide inactivation

M. Reboud-Ravaux, J. Mazaleyrat, M. Wakselman, 1988 .

New axially chiral atropos and tropos secondary diamines as ligands for enantioselective intramolecular hydroamination

J. Collin, K. Wright, J. Mazaleyrat, 2008 .

Binaphthyl substituted 1,8-bis(dimethylamino)naphthalenes, the first chiral, atropisomeric, proton sponges

K. Wright, J. Mazaleyrat, 2008 .

The Williamson Reaction: A New and Efficient Method for the Alternate Resolution of 2,2'-Bis(bromomethyl)-1,1'-binaphthyl and 1,1'-Binaphthalene-2,2'-diol.

J. Mazaleyrat, M. Wakselman, 1996, The Journal of organic chemistry.

Synthesis of Enantiomerically Pure cis‐ and trans‐4‐Amino‐1‐oxyl‐2,2,6,6‐tetramethylpiperidine‐3‐carboxylic Acid: A Spin‐Labelled, Cyclic, Chiral β‐Amino Acid, and 3D‐Structural Analysis of a Doubly Spin‐Labelled β‐Hexapeptide

C. Corvaja, C. Toniolo, F. Formaggio, 2007 .

4-Amino-1-oxyl-2,2,6,6-tetramethylpiperidine-3-carboxylic acid (β-TOAC), the first spin-labelled, cyclic, chiral β-amino acid resolved in an enantiomerically pure state

C. Toniolo, M. Crisma, K. Wright, 2003 .

Selective hydrogenolysis of the benzyloxycarbonyl protecting group of Nϵ-lysine in cyclopeptides containing a benzylic phenyl ether function. Evidence for Nϵ-methylated lysine side products.

Juan Xie, J. Mazaleyrat, M. Wakselman, 1992 .

Chiral catalysis of additions of alkyllithiums to aldehydes

D. Cram, J. Mazaleyrat, 1981 .

Central-to-axial chirality transfer and induced circular dichroism in 6,7-dihydro-5H-dibenz[c,e]azepine derivatives of α- and β-amino esters

C. Toniolo, F. Formaggio, K. Wright, 2008 .

Synthesis and resolution of axially chiral C2-symmetric 1,1′-binaphthyl-substituted tetramethylethylenediamines

J. Mazaleyrat, 1997 .

Induced Axial Chirality in the Biphenyl Core of the Proatropoisomeric, Cα‐Tetrasubstituted α‐Amino Acid Residue Bip in Peptides

C. Toniolo, F. Formaggio, M. Crisma, 2005 .

Methode simple de synthese d'agents de transfert chiraux par action d'un agent alkylant a squelette binaphtyle-1,1′

J. Mazaleyrat, 1983 .

Practical resolution of an atropoisomeric α,α-disubstituted glycine with l-phenylalanine cyclohexylamide as chiral auxiliary

J. Mazaleyrat, M. Wakselman, A. Gaucher, 1998 .

Asymmetric nucleophilic acylation via metalated .alpha.-aminonitriles possessing an axially disymmetric tertiary amino group

J. Mazaleyrat, Z. Welvart, N. Maigrot, 1985 .

New and improved synthesis of optically pure (R)- and (S)-2,2'-dimethyl-1,1'-binaphthyl and related compounds

J. Mazaleyrat, N. Maigrot, 1985 .

Reductive cleavage of axially disymmetric tertiary amines and quaternary ammonium salts by lithium aluminium hydride. Synthesis of new 1,1′-binaphthyl substituted amines

J. Mazaleyrat, N. Maigrot, F. Cottineau, 1985 .

Towards peptide versions of Cram's host–guest chemistry: the synthesis of Cα,α-disubstituted glycines with binaphthol-based crowned side-chains

K. Wright, J. Mazaleyrat, M. Wakselman, 2003 .

New crown-carrier C a,a-disubstituted glycines derived from a-methyl-( l)-DOPA

K. Wright, J. Mazaleyrat, M. Wakselman, 2002 .

Anti-HIV activity of N-(2,3-dihalogenopropyl)- and N-allyl-glycine containing pentapeptides.

A. Bousseau, Juan Xie, J. Mazaleyrat, 1994 .

Preparation of N-Boc N-Alkyl Glycines for Peptoid Synthesis

Juan Xie, J. Mazaleyrat, M. Wakselman, 1994 .

9-Amino-4,5-diazafluorene-9-carboxylic Acid (Daf), a New Cα,α-Disubstituted Glycine Containing a Spatially Constrained Bipyridine-Like Ligand for Transition Metals − Synthesis and Evaluation of Peptide-Coupling Conditions at itsC- andN-Termini

C. Toniolo, F. Formaggio, M. Crisma, 2001 .

Chiral catalysis of additions of alkyllithiums to aldehydes

D. Cram, J. Mazaleyrat, 1981 .

Induced axial chirality in the biphenyl core of the cα-tetrasubstituted α-amino acid residue Bip and subsequent propagation of chirality in (Bip)n/Val oligopeptides

C. Toniolo, F. Formaggio, S. Oancea, 2004 .

Synthesis of a,a-disubstituted--aminoacids with axial chirality

J. Mazaleyrat, M. Wakselman, A. Gaucher, 1998 .

A new tool for photoaffinity labeling studies: a partially constrained, benzophenone based, alpha-amino acid.

C. Toniolo, F. Formaggio, M. Crisma, 2010, Organic & biomolecular chemistry.

Synthesis of terminally protected (S)-β3-H-DOPA by Arndt–Eistert homologation: an approach to crowned β-peptides

J. Mazaleyrat, M. Wakselman, A. Gaucher, 2005 .

Synthesis of enantiopure, axially chiral, Cα-tetrasubstituted α-amino acids with binaphthyl-based crowned side chains and 3D-structural analysis of their peptides

C. Toniolo, F. Formaggio, K. Wright, 2008 .

New tools for the control of peptide conformation and supramolecular chemistry: crown-carrier, C(alpha)-methyl L-DOPA amino acids.

C. Toniolo, F. Formaggio, M. Crisma, 2003, Biopolymers.

Synthesis of the First Axially Dissymmetric, Cα,α-Disubstituted Glycine Containing a Crown Ether Receptor, and the Conformational Preferences of a Model Peptide

C. Toniolo, F. Formaggio, C. Peggion, 2002 .

Synthesis and resolution of β2,2-HBin, the first enantiomerically stable β-amino acid with chirality only due to axial dissymmetry

D. Cabaret, J. Mazaleyrat, M. Wakselman, 2001 .

A new chiral α-aminoacid with only axial dissymmetry: Synthesis and X-ray analysis of a 1,1′-binaphthyl-substituted α-aminoisobutyric acid (Bin) and of its biphenyl analogue (Bip)

L. Tchertanov, J. Guilhem, J. Mazaleyrat, 1996 .

Synthesis, conformational study, and spectroscopic characterization of the cyclic Cα,α‐disubstituted glycine 9‐amino‐9‐fluorenecarboxylic acid

C. Toniolo, F. Formaggio, M. Crisma, 1999 .

Synthesis and enzymic hydrolysis of cyclic peptides containing an anthranilic acid residue.

M. Reboud-Ravaux, J. Mazaleyrat, M. Wakselman, 2009, International journal of peptide and protein research.

Recent contributions of electronic circular dichroism to the investigation of oligopeptide conformations.

C. Toniolo, F. Formaggio, M. Crisma, 2004, Chirality.

Synthesis of terminally protected 9-amino-4,5-diazafluorene-9-carboxylic acid, the first rigid, transition-metal receptor, Cα,α-disubstituted glycine

C. Toniolo, F. Formaggio, M. Crisma, 1999 .

The Bip method, based on the induced circular dichroism of a flexible biphenyl probe in terminally protected -Bip-Xaa*- dipeptides, for assignment of the absolute configuration of beta-amino acids.

C. Toniolo, F. Formaggio, K. Wright, 2008, Journal of the American Chemical Society.

Synthesis and spectroscopic characterization of enantiopure protected trans-4-amino-1-oxyl-2,2,6,6-tetramethyl piperidine-3-carboxylic acid (trans β-TOAC)

C. Toniolo, F. Formaggio, A. Toffoletti, 2005 .

An extension of the ‘Bip method’: induced axial chirality in a series of dipeptides based on Bip/β2,2-HBip combined with Ala/β3-HAla

C. Toniolo, F. Formaggio, S. Oancea, 2006 .

Synthesis of linear and cyclic homo-β-peptides based on a binaphthylic β-amino acid with only axial chirality

C. Toniolo, F. Formaggio, M. Crisma, 2006 .

High-performance liquid chromatographic separation of novel atropic α,α-disubstituted-β-amino acids, either on different β-cyclodextrin-bonded phases or as their 1-fluoro-2,4-dinitrophenyl-5-l-alanine amide derivatives

D. Armstrong, A. Péter, J. Mazaleyrat, 1999 .

Novel α,α-disubstituted α-aminoacids with axial dissymmetry and their N- or C-protected derivatives

J. Mazaleyrat, M. Wakselman, A. Gaucher, 1997 .

Liquid chromatographic enantioseparation of spin-labelled β-amino acids

K. Wright, A. Péter, J. Mazaleyrat, 2003 .

Synthesis of protected derivatives and short peptides of antAib, a novel Cα-tetrasubstituted α-amino acid of the Ac5c type possessing a fused anthracene fluorophore

C. Toniolo, F. Formaggio, K. Wright, 2006 .

Synthesis, conformational analysis, and spectroscopic characterization of peptides based on Daf, the first rigid transition-metal receptor, cyclic Cα,α-disubstituted glycine

C. Toniolo, F. Formaggio, M. Crisma, 2002 .

Synthesis of [18-C-6]-β3-(L)-DOPA, first β-amino acid with a crown-ether receptor side-chain

K. Wright, L. Vandromme, J. Mazaleyrat, 2002 .

High diastereoselectivity in the reaction of α-aminonitriles bearing an (S)-(+)-2-methoxymethylpyrrolidine group with Grignard reagents

J. Mazaleyrat, Z. Welvart, N. Maigrot, 1984 .

Participation of a peri‐Hydroxyl Group in the Trifluoroacetolysis of Naphthalenesulfonamides.

J. Mazaleyrat, M. Wakselman, 1986 .

Peptoid mimics of a C2-symmetric inhibitor of the HIV-1 protease.

J. Mazaleyrat, M. Wakselman, Y. Lelièvre, 1994 .

High-performance liquid chromatographic separation of enantiomers of 1,1′-binaphthyl-substituted α-aminoisobutyric acid

A. Péter, J. Mazaleyrat, M. Wakselman, 1997 .

Synthesis, resolution and assignment of absolute configuration of trans 3-amino-1-oxyl-2,2,5,5-tetramethylpyrrolidine-4-carboxylic acid (POAC), a cyclic, spin-labelled β-amino acid

C. Toniolo, F. Formaggio, M. Crisma, 2008 .

First access to the spin-labelled β-amino acid POAC in an enantiopure state by resolution through its binaphthyl esters

C. Toniolo, F. Formaggio, K. Wright, 2003 .

Afc can adopt either the fully extended or a turn conformation

C. Toniolo, F. Formaggio, M. Crisma, 2000, Letters in Peptide Science.

Peptides Based on Daf, the First Rigid, Transition-Metal Receptor: Cα,α-Disubstituted Glycine

C. Toniolo, F. Formaggio, M. Crisma, 2001 .

Synthesis and conformational characterisation of hexameric β-peptide foldamers by using double POAC spin labelling and cw-EPR.

L. Franco, C. Toniolo, F. Formaggio, 2010, Chemistry.

N-t-Boc 6-amino-1,11-(20-crown-6)-6,7-dihydro-5H-dibenzo[a,c] cycloheptene-6-carboxylic acid methyl ester, the first prototype of a crown-carrier-axially dissymmetric-α,α-disubstituted glycine

J. Mazaleyrat, M. Wakselman, A. Gaucher, 1997 .

First Peptide‐Based System of Rigid Donor–Rigid Interchromophore Spacer–Rigid Acceptor: A Structural and Photophysical Study

C. Toniolo, F. Formaggio, M. Crisma, 1999 .

A combined spectroscopic and theoretical study of a series of conformationally restricted hexapeptides carrying a rigid binaphthyl-nitroxide donor-acceptor pair.

C. Toniolo, F. Formaggio, C. Mazzuca, 2003, Chemistry.

Bip: a Cα-Tetrasubstituted, Axially Chiral α-Amino Acid. Synthesis and Conformational Preference of Model Peptides

C. Toniolo, F. Formaggio, M. Crisma, 2000 .

CIDEP effects of intramolecular quenching of singlet and triplet excited states by nitroxide radicals in oligopeptides: a potentially useful new method for investigating peptide secondary structures in solution.

C. Corvaja, C. Toniolo, F. Formaggio, 2000, Chemistry.

Regio- and stereoselectivity of chiral binaphthyl reductive aminoalkylation. Rotational conformation and electron distribution of alkali-metal biarylides

O. Eisenstein, M. Tordeux, J. Mazaleyrat, 1977 .

Dipeptidyl-peptidase IV-beta--further characterization and comparison to dipeptidyl-peptidase IV activity of CD26.

J. Blanco, E. Jacotot, A. Hovanessian, 1998, European journal of biochemistry.

Synthesis, conformational study, and spectroscopic characterization of the cyclic Cα,α‐disubstituted glycine 9‐amino‐9‐fluorenecarboxylic acid

C. Toniolo, F. Formaggio, M. Crisma, 1999 .

Synthesis and characterisation of helical beta-peptide architectures that contain (S)-beta3-HDOPA(Crown Ether) derivatives.

C. Toniolo, F. Formaggio, C. Peggion, 2008, Chemistry.

A Chirally Stable, Atropoisomeric,Cα-Tetrasubstitutedα-Amino Acid: Incorporation into Model Peptides and Conformational Preference

C. Toniolo, F. Formaggio, M. Crisma, 2001 .