W. Baker

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Fosfomycin Enhances the Active Transport of Tobramycin in Pseudomonas aeruginosa

J. Velayudhan, D. Macleod, T. Kenney, 2012, Antimicrobial Agents and Chemotherapy.

Rapid screening of natural products for antimycobacterial activity by using luciferase-expressing strains of Mycobacterium bovis BCG and Mycobacterium intracellulare

M. Hickey, C. K. Stover, L. Mitscher, 1997, Antimicrobial agents and chemotherapy.

Discovery of a well-absorbed, efficacious renin inhibitor, A-74273.

P. Kovar, H. Kleinert, J. Polakowski, 1992, Hypertension.

Cardiovascular Effects and Hemodynamic Mechanism of Action of the Novel, Nonpeptidic Renin Inhibitor A‐74273 in Dogs

P. Kovar, H. Kleinert, J. Wessale, 1993, Journal of cardiovascular pharmacology.

Chapter 17. Recent Advances in the Chemistry and Biology of Anti-mycobacterial Agents

C. K. Stover, L. Mitscher, W. Baker, 1996 .

The In Vitro Pharmacology of GS-5759, A Novel Bifunctional Phosphodiesterase 4 Inhibitor and Long Acting β2-Adrenoceptor Agonist

M. Salmon, G. Phillips, C. Wright, 2014, The Journal of Pharmacology and Experimental Therapeutics.

GS-424020 – A Novel Mutual Prodrug Of Salmeterol And Desisobutrylciclesonide Attenuates Acute Bronchoconstriction In The Absence Of Cardiovascular Side-Effects In Ragweed Sensitized And Naïve Dogs

P. Kuehl, K. Rudolph, M. Campen, 2010, ATS 2010.

Effects of angiotensinase inhibitors on plasma protein binding and IC50 determinations of renin inhibitors.

S. Rosenberg, B. Dayton, W. Baker, 1992, Clinical chemistry.

A search for novel chemotherapy against tuberculosis amongst natural products

L. Mitscher, W. Baker, 1998 .

A prodrug approach toward the development of water soluble fluoroquinolones and structure--activity relationships of quinoline-3-carboxylic acids.

J. Therrien, W. Baker, R. Shawar, 2004, Journal of medicinal chemistry.

A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis

Clifton E. Barry, William R. Baker, D. Sherman, 2000, Nature.

Synthesis and Structure Determination of (3S, 5S)-2,3,5,6-Tetrahydro-3,5-dialkyl-N-(tert-butyloxycarbonyl)-4H-1,4-oxazine-2-ones

S. Spanton, W. Baker, S. L. Condon, 1992 .

Discovery of a peptide-based renin inhibitor with oral bioavailability and efficacy.

P. Kovar, S. Rosenberg, H. Kleinert, 1992, Science.

Dipeptide isosteres. 2. Synthesis of hydroxyethylene dipeptide isostere diastereomers from a common γ-lactone intermediate. Preparation of renin and HIV-1 protease inhibitor transition state mimics.☆

J. Pratt, W. Baker, 1993 .

Design of a well-absorbed renin inhibitor.

D. Egan, S. Rosenberg, H. Kleinert, 1991, Journal of medicinal chemistry.

Annelative ring expansion via intramolecular [2 + 2] photocycloaddition of .alpha.,.beta.-unsaturated .gamma.-lactones and reductive cleavage: synthesis of hydrocyclopentacyclooctene-5-carboxylates

P. Senter, W. Baker, R. Coates, 1982 .

Annelative ring expansion via intramolecular [2 + 2] photocycloaddition of α,β-unsaturated γ-lactones and reductive cleavage

P. Senter, W. Baker, R. Coates, 1982 .

The design and synthesis of cyclic renin inhibitors

Charles W. Hutchins, William R. Baker, C. Hutchins, 1991 .

1,2,3-trisubstituted cyclopropanes as conformationally restricted peptide isosteres: application to the design and synthesis of novel renin inhibitors.

S. Rosenberg, R. Austin, W. Baker, 1992, Journal of medicinal chemistry.

Antitubercular natural products: berberine from the roots of commercial Hydrastis canadensis powder. Isolation of inactive 8-oxotetrahydrothalifendine, canadine, beta-hydrastine, and two new quinic acid esters, hycandinic acid esters-1 and -2.

L. Mitscher, L A Mitscher, D. Velde, 1998, Journal of natural products.

Antibacterial activities of a fosfomycin/tobramycin combination: a novel inhaled antibiotic for bronchiectasis

J. Burns, Jesse L. Gurgel, D. Macleod, 2009, The Journal of antimicrobial chemotherapy.

Dipeptide isosteres. 1. Synthesis of dihydroxyethylene dipeptide isosteres via diastereoselective additions of alkyllithium reagents to N,N-dimethylhydrazones. Preparation of renin and HIV-1 protease inhibitor transition-state mimics

W. Baker, S. L. Condon, 1993 .

C-terminal modifications of nonpeptide renin inhibitors: improved oral bioavailability via modification of physicochemical properties.

D. Egan, W. Baker, J. Cohen, 1992, Journal of medicinal chemistry.

Stereoselective syntheses of hydroxyethylene dipeptide isosteres

W. Baker, R. Mantei, C. Hsiao, 1991 .

Dipeptide Isosters. Part 1. Synthesis of Dihydroxyethylene Dipeptide Isosters via Diastereoselective Additions of Alkyllithium Reagents to N,N-Dimethylhydrazones. Preparation of Renin and HIV-1 Protease Inhibitor Transition-State Mimics.

W. Baker, S. L. Condon, 1993 .

Renin inhibitors: C-terminal oxetanes as potent transition-state mimics.

S. Rosenberg, H. Kleinert, W. Baker, 1994, Bioorganic & medicinal chemistry.

A Practical Synthesis of the Dihydroxyethylene Dipeptide Isostere, (2S, 3R, 4S) 2-[(tert-Butyloxycarbonyl)amino]-1-cyclohexyl-3,4-dihydroxy-6-methylheptane, from D-Isoascorbic Acid

W. Baker, S. L. Condon, 1992 .

Synthesis of [14C]A‐62514, a radiolabelled derivative of erythromycin a, via [2‐14C]N, N‐dimethylethylenediamine

W. Baker, B. Surber, L. Seif, 1991 .

A diastereoselective synthesis of pseudo-C2 -symmetric 1,3-diamino-2-propanols as core units in HIV protease inhibitors

S. Wittenberger, W. Baker, B. G. Donner, 1993 .

A Diastereoselective Synthesis of Pseudo‐C2‐Symmetric 1,3‐Diamino‐2‐ propanols as Core Units in HIV Protease Inhibitors.

S. Wittenberger, W. Baker, B. G. Donner, 2010 .

Nonpeptide renin inhibitors with good intraduodenal bioavailability and efficacy in dog.

J. Wessale, K. Verburg, W. Baker, 1994, Journal of medicinal chemistry.

Slow, tight binding to human renin of some nonpeptidic renin inhibitors containing a 4‐methoxymethoxypiperidinylamide at the P4 position

S. Rosenberg, B. Dayton, H. Kleinert, 1992, FEBS letters.

ORALLY BIOAVAILABLE PEPTIDELIKE MOLECULES : A CASE HISTORY

H. Kleinert, W. Baker, H. Stein, 1993 .

Synthesis of the Nonpeptide Renin Inhibitor A-68064 and the ACE Inhibitor Methyl Enalaprilat from (5S)-2,3,5,6-Tetrahydro-5-alkyl-N-(tert-butyloxycarbonyl-4H-1,4-oxazine-2-ones

W. Baker, S. L. Condon, 1992 .

Modification of macrolide antibiotics. Synthesis of 11-deoxy-11-(carboxyamino)-6-O-methylerythromycin A 11,12-(cyclic esters) via an intramolecular Michael reaction of O-carbamates with an α,β-unsaturated ketone

R. Stephens, Jerry D. Clark, W. Baker, 1988 .

New macrolides active against Streptococcus pyogenes with inducible or constitutive type of macrolide-lincosamide-streptogramin B resistance

P. Fernandes, D. Hardy, E. McDonald, 1989, Antimicrobial Agents and Chemotherapy.

Modification of Macrolide Antibiotics. Synthesis of 11-Deoxy-11-(carboxyamino)-6-O-methylerythromycin A. 11,12-(Cyclic Esters) via an Intramolecular Michael Reaction of O-Carbamates with an α,β-Unsaturated Ketone.

R. Stephens, Jerry D. Clark, W. Baker, 1988 .

Nonantibiotic macrolides prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume depletion.

Alaina L. Garland, R. Tarran, G. Phillips, 2013, American journal of physiology. Lung cellular and molecular physiology.

Synthesis of 4,5,6,7-tetrahydro-1(3H)-isobenzofuranones by reaction of N,N-dimethyl-2-lithio-1-cyclohexenecarboxamide with aldehydes and ketones

W. Baker, R. Coates, 1979 .

(1 alpha, 2 beta, 3 beta, 4 alpha)-1,2-bis[N-propyl-N-(4-phenoxybenzyl) amino]carbonyl]cyclobutane-3,4-dicarboxylic acid (A-87049): a novel potent squalene synthase inhibitor.

D. Garvey, S. Rosenberg, S. Fakhoury, 1997, Journal of medicinal chemistry.

The in vivo efficacy and side effect pharmacology of GS-5759, a novel bifunctional phosphodiesterase 4 inhibitor and long-acting β2-adrenoceptor agonist in preclinical animal species

J. McDonald, M. Salmon, Kim Hartsough, 2014, Pharmacology research & perspectives.

Organic reactions at high pressure. The Diels-Alder reaction of p-benzoquinone with dienic esters

W. G. Dauben, W. Baker, 1982 .

Conformationally restricted peptide isosteres. 2.1 Synthesis and in vitro potency of dipeptide renin inhibitors employing a 2-alkylsulfonyl-3-phenylcyclopropane carboxamide as a P3 amino acid replacement ☆

Stephen R. Martin, H. Kleinert, W. Baker, 1992 .

Design of rigid heterocyclic phenylalanine replacements for incorporation into renin inhibitors

D. Kempf, J. Plattner, H. Kleinert, 1990 .

Fosfomycin Enhances the Active Transport of Tobramycin in Pseudomonas aeruginosa

J. Velayudhan, T. Kenney, J. Therrien, 2012, Antimicrobial Agents and Chemotherapy.