P. Ulrich

发表

Spermine Inhibits Proinflammatory Cytokine Synthesis in Human Mononuclear Cells: A Counterregulatory Mechanism that Restrains the Immune Response

K. Tracey, Minghuang Zhang, G. Botchkina, 1997, The Journal of experimental medicine.

Nonclinical Safety Assessment of CFZ533, a Fc-Silent Anti-CD40 Antibody, in Cynomolgus Monkeys

P. Espié, J. Rush, T. Flandre, 2018, Toxicological sciences : an official journal of the Society of Toxicology.

Characterization of the in vitro and in vivo properties of CFZ533, a blocking and non‐depleting anti‐CD40 monoclonal antibody

S. Côté, F. Kolbinger, P. Espié, 2018, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Modulation of the activity of human monocyte-derived dendritic cells by chemical haptens, a metal allergen, and a staphylococcal superantigen.

A. Cordier, P. Ulrich, K. Coutant, 1999, Toxicological sciences : an official journal of the Society of Toxicology.

Contact allergens and irritants show discrete differences in the activation of human monocyte-derived dendritic cells: consequences for in vitro detection of contact allergens

O. Grenet, P. Bruegger, P. Ulrich, 2004, Archives of Toxicology.

Nonclinical Development of Biologics: Integrating Safety, Pharmacokinetics, and Pharmacodynamics to Create Smarter and More Flexible Nonclinical Safety Programs Optimizing Animal Use

B. Rattel, A. Kiessling, L. Weir, 2021, International journal of toxicology.

Synthesis of the trypanosomatid metabolites trypanothione, and N1-mono- and N8-mono-glutathionylspermidine

A. Fairlamb, A. Cerami, G. Henderson, 1986 .

Biotherapeutics in non‐clinical development: Strengthening the interface between safety, pharmacokinetics‐pharmacodynamics and manufacturing

A. Kiessling, J. Tibbitts, L. Weir, 2018, Regulatory toxicology and pharmacology : RTP.

Novel pyrroles from sulfite-inhibited Maillard reactions: insight into the mechanism of inhibition

A. Cerami, P. Ulrich, J. Farmar, 1988 .

The Second ECVAM Workshop on Phototoxicity Testing

D. Averbeck, N. Gibbs, H. Spielmann, 2000, Alternatives to laboratory animals : ATLA.

Non-clinical Safety Evaluation of Biotherapeutics - Challenges, Opportunities and new Insights.

E. Tarcsa, L. de Haan, J. Tibbitts, 2016, Regulatory toxicology and pharmacology : RTP.

CNI-H0294, a Nuclear Importation Inhibitor of the Human Immunodeficiency Virus Type 1 Genome, Abrogates Virus Replication in Infected Activated Peripheral Blood Mononuclear Cells

M. Bukrinsky, A. Cerami, S. Nadler, 1998, Antimicrobial Agents and Chemotherapy.

Topical FK506 suppresses cytokine and costimulatory molecule expression in epidermal and local draining lymph node cells during primary skin immune responses.

H. Schuppe, T. Ruzicka, B. Homey, 1998, Journal of immunology.

Primary Skin Immune Responses and Local Draining Lymph Node Cells During Costimulatory Molecule Expression in Epidermal Topical FK 506 Suppresses Cytokine and

H. Schuppe, T. Ruzicka, B. Homey, 1998 .

Epidermal growth factor--interactions with normal and malignant urothelium: in vivo and in situ studies.

E. Messing, P. Hanson, P. Ulrich, 1987, The Journal of urology.

Protection against lethal polymicrobial sepsis by CNI-1493, an inhibitor of pro-inflammatory cytokine synthesis

K. Tracey, G. Botchkina, P. Ghezzi, 1997 .

Validation of immune function testing during a 4-week oral toxicity study with FK506.

E. Perentes, D. Roman, A. Mahl, 2003, Toxicology letters.

Utilization of irritation data in the local lymph node assay

P. Ulrich, H. Vohr, 2007 .

A modified murine local lymph node assay for the differentiation of contact photoallergy from phototoxicity by analysis of cytokine expression in skin-draining lymph node cells.

B. Homey, H W Vohr, P Ulrich, 1998, Toxicology.

Intralaboratory validation of alternative endpoints in the murine local lymph node assay for the identification of contact allergic potential: primary ear skin irritation and ear-draining lymph node hyperplasia induced by topical chemicals

P. Ulrich, J. Streich, W. Suter, 2001, Archives of Toxicology.

Design and evaluation of immunotoxicity studies.

D. Roth, E. Perentes, D. Roman, 2006, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Nuclear Localization Signal of HIV-1 as a Novel Target for Therapeutic Intervention

G. Nuovo, M. Bukrinsky, A. Cerami, 1995, Molecular medicine.

Testosterone-induced susceptibility to Plasmodium chabaudi malaria: persistence after withdrawal of testosterone.

F. Wunderlich, W. Kühn‐Velten, P. Ulrich, 1997, The Journal of endocrinology.

An agent cleaving glucose-derived protein crosslinks in vitro and in vivo

J. Bernhagen, R. Bucala, A. Cerami, 1996, Nature.

An Inhibitor of Macrophage Arginine Transport and Nitric Oxide Production (CNI-1493) Prevents Acute Inflammation and Endotoxin Lethality

K. Tracey, M. Bukrinsky, R. Bucala, 1995, Molecular medicine.

Early changes in murine epidermal cell phenotype by contact sensitizers.

A Cordier, A. Cordier, K D Coutant, 1999, Toxicological sciences : an official journal of the Society of Toxicology.

The use of recovery animals in nonclinical safety assessment studies with monoclonal antibodies: further 3Rs opportunities remain.

M. Leach, P. van Meer, L. de Haan, 2023, Regulatory toxicology and pharmacology : RTP.

Novel Pyrroles from Sulfite-Inhibited Maillard Reactions: Insight into the Mechanism of Inhibition.

A. Cerami, P. Ulrich, J. Farmar, 1988 .

3RD EUROPEAN CONGRESS OF TOXICOLOGIC PATHOLOGY, 2005, COPENHAGEN, DENMARK Design and evaluation of immunotoxicity studies

E. Perentes, D. Roman, A. Mahl, 2006 .

Re-evaluating the need for chronic toxicity studies with therapeutic monoclonal antibodies, using a weight of evidence approach.

M. Leach, P. van Meer, L. de Haan, 2022, Regulatory toxicology and pharmacology : RTP.

In vitro and in vivo antimalarial activity of amphiphilic naphthothiazolium salts with amine-bearing side chains.

D. Sullivan, A. Tripathi, Gregory R. Gipson, 2014, The American journal of tropical medicine and hygiene.

Cytokine expression profiles during murine contact allergy: T helper 2 cytokines are expressed irrespective of the type of contact allergen

P. Ulrich, O. Grenet, W. Suter, 2001, Archives of Toxicology.

Integrated preclinical photosafety testing strategy for systemically applied pharmaceuticals.

D. Bauer, B. Kittel, P. Ulrich, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Development of the ICH Guidelines for Immunotoxicology Evaluation of Pharmaceuticals Using a Survey of Industry Practices

H. van Loveren, J. Sawada, J. W. van der Laan, 2005, Journal of immunotoxicology.

Nonclinical safety testing of biopharmaceuticals--Addressing current challenges of these novel and emerging therapies.

Peter Ulrich, Frank R Brennan, L. de Haan, 2015, Regulatory toxicology and pharmacology : RTP.

Pharmacological Reversal Of AGE-Related Protein Crosslinking with Agents that Cleave α-Dicarbonyls

P. Ulrich, 2005 .

An European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: first round.

H. van Loveren, R. Vandebriel, A. Gamer, 2005, Toxicology.

DEVELOPMENT OF A SELECTIVE INHIBITOR OF CYTOKINE‐INDUCIBLE L‐ARGININE TRANSPORT (CNI‐1493) THAT BLOCKS MACROPHAGE PRODUCTION OF NO AND TNF&agr;, AND PROTECTS AGAINST LPS LETHALITY.: 31

K. Tracey, A. Cerami, M. Bianchi, 1995 .