D. Shields

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Efficient cleavage and segregation of nascent presecretory proteins in a reticulocyte lysate supplemented with microsomal membranes.

G. Blobel, D. Shields, 1978, The Journal of biological chemistry.

A role for clathrin in reassembly of the Golgi apparatus.

D. Shields, A. Radulescu, A. Siddhanta, 2006, Molecular biology of the cell.

Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons.

P. Greengard, W. Netzer, Huaxi Xu, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Variable stabilities and recoveries of rat-liver RNA polymerases A and B according to growth status of the tissue.

J. Tata, D. Shields, J. R. Tata, 1976, European journal of biochemistry.

Cell-free synthesis of fish preproinsulin, and processing by heterologous mammalian microsomal membranes.

G. Blobel, D. Shields, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Clathrin is required for postmitotic Golgi reassembly

D. Shields, A. Radulescu, Andreea E. Radulescu, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cell-free biosynthesis of multiple preprosomatostatins: characterization by hybrid selection and amino-terminal sequencing.

D. Shields, T. Warren, 1984, Biochemistry.

Fragmentation of the Golgi Apparatus

J. Morrow, M. Stankewich, Michael C. Stankewich, 2003, The Journal of Biological Chemistry.

Biosynthesis and Packaging of Carboxypeptidase D into Nascent Secretory Vesicles in Pituitary Cell Lines*

L. Fricker, O. Varlamov, D. Shields, 1999, The Journal of Biological Chemistry.

Cell-free processing and segregation of insulin precursors.

D. Shields, E. Eskridge, 1983, The Journal of biological chemistry.

Substance P and somatostatin coexist within neuritic plaques: Implications for the pathogenesis of Alzheimer's disease

W. Benzing, R. Terry, D. Armstrong, 1989, Neuroscience.

Prohormone processing in the trans-Golgi network: endoproteolytic cleavage of prosomatostatin and formation of nascent secretory vesicles in permeabilized cells

H. Xu, D. Shields, Huaxi Xu, 1993, The Journal of cell biology.

Prosomatostatin Processing in Permeabilized Cells

D. Shields, C. D. Austin, 1996, The Journal of Biological Chemistry.

The propeptide of preprosomatostatin mediates intracellular transport and secretion of alpha-globin from mammalian cells

D. Shields, T. Stoller, 1989, The Journal of cell biology.

Truncations of a secretory protein define minimum lengths required for binding to signal recognition particle and translocation across the endoplasmic reticulum membrane.

D. Shields, E. Eskridge, M. Okun, 1990, The Journal of biological chemistry.

Mouse myeloma cells that make short immunoglobulin heavy chains: pleiotropic effects on glycosylation and chain assembly

A. Kenter, B. Birshtein, D. Shields, 1984, The Journal of cell biology.

ADP-ribosylation Factor-1 Stimulates Formation of Nascent Secretory Vesicles from the trans-Golgi Network of Endocrine Cells (*)

Ye Guang Chen, D. Shields, Ye-Guang Chen, 1996, The Journal of Biological Chemistry.

Post-translational modifications of the rat mammary gland caseins: in vitro synthesis, processing, and segregation.

J. Rosen, A. Steinberger, E. Steinberger, 1980 .

Evidence of a novel dipeptidyl aminopeptidase in mammalian GH(3) cells: new insights into the processing of peptide hormone precursors.

Sangyoon Han, S. Hong, D. Shields, 2002, Cell structure and function.

The use of permeabilized cells to investigate secretory granule biogenesis.

D. Shields, A. Siddhanta, W. Ling, 1998, Methods.

Formation of nascent secretory vesicles from the trans-Golgi network of endocrine cells is inhibited by tyrosine kinase and phosphatase inhibitors

D. Shields, C. D. Austin, Cary D. Austin, 1996, The Journal of cell biology.

In vitro biosynthesis of fish islet preprosomatostatin: evidence of processing and segregation of a high molecular weight precursor.

D. Shields, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Prohormone processing in permeabilized cells: endoproteolytic cleavage of prosomatostatin in the trans-Golgi network.

H. Xu, D. Shields, H. Xu, 1994, Biochimie.

Sodium butyrate stimulates somatostatin production by cultured cells.

D. Shields, R. Green, 1984, Endocrinology.

Retrovirus-mediated expression of preprosomatostatin: posttranslational processing, intracellular storage, and secretion in GH3 pituitary cells

D. Shields, T. Stoller, 1988, The Journal of cell biology.

Effects of α-Amanitin in vivo on RNA Polymerase and Nuclear RNA Synthesis

J. Tata, M. Hamilton, D. Shields, 1972 .

Expression of Preprosomatostatin in Foreign Cells: Secretion of Mature Somatostatin by Yeast (Saccharomyces Cerevisiae)

M. Schaber, R. Kramer, D. Shields, 1987 .

Somatostatin discriminates between the intracellular pathways of secretory and membrane proteins

D. Shields, R. Green, 1984, The Journal of cell biology.

Prosomatostatin processing in permeabilized cells. Endoproteolytic cleavage is mediated by a vacuolar ATPase that generates an acidic pH in the trans-Golgi network.

H. Xu, D. Shields, H. Xu, 1994, The Journal of biological chemistry.

Inhibition of Phosphatidic Acid Synthesis Alters the Structure of the Golgi Apparatus and Inhibits Secretion in Endocrine Cells*

J. Backer, D. Shields, A. Siddhanta, 2000, The Journal of Biological Chemistry.

The Propeptide of Anglerfish Preprosomatostatin-I Rescues Prosomatostatin-II from Intracellular Degradation (*)

Y. G. Chen, A. Danoff, D. Shields, 1995, The Journal of Biological Chemistry.

Expression of preprosomatostatin in heterologous cells: Biosynthesis, posttranslational processing, and secretion of mature somatostatin

D. Shields, T. Warren, 1984, Cell.

The NH2 terminus of preproinsulin directs the translocation and glycosylation of a bacterial cytoplasmic protein by mammalian microsomal membranes

D. Shields, E. Eskridge, 1986, The Journal of cell biology.

"Slip, sliding away": phospholipase D and the Golgi apparatus.

Z. Freyberg, D. Shields, A. Siddhanta, 2003, Trends in cell biology.

Retrovirus-Mediated Expression of Preprosomatostatin in Rat Pituitary GH3 Cells: Targeting of Somatostatin to the Regulated Secretory Pathway

N. Fleischer, D. Shields, H. Liker, 1989, Molecular endocrinology.

Caspase cleavage of phospholipase D1 in vitro alters its regulation and reveals a novel property of the "loop" region.

S. Bourgoin, C. Riebeling, D. Shields, 2008, Biochimica et biophysica acta.

Phospholipase D2 is localized to the rims of the Golgi apparatus in mammalian cells.

Z. Freyberg, S. Bourgoin, D. Shields, 2002, Molecular biology of the cell.

Intracellular localization of phospholipase D1 in mammalian cells.

Z. Freyberg, M. Frohman, S. Bourgoin, 2001, Molecular biology of the cell.

Expression of Preprosomatostatin Genes in Heterologous Cells

D. Shields, R. Green, 1986 .

Fragmentation and Re-assembly of the Golgi Apparatus in Vitro

D. Shields, A. Siddhanta, D. Sweeney, 2002, The Journal of Biological Chemistry.

Differential translation of two distinct preprosomatostatin messenger RNAs.

D. Shields, A. Danoff, 1988, The Journal of biological chemistry.

Cell-free synthesis and processing of multiple precursors to glucagon

D. Shields, T. Warren, Sara E. Roth, 1981, Nature.

Phospholipase D Stimulates Release of Nascent Secretory Vesicles from the trans-Golgi Network

S. Hammond, Ye Guang Chen, M. Frohman, 1997, The Journal of cell biology.

Differential thermal sensitivities of eukaryotic DNA‐dependent RNA polymerases

J. Tata, D. Shields, 1973, FEBS letters.

Association of messenger ribonucleic acid with mammalian microsomal membranes: characterization by analysis of cell-free translation products.

D. Shields, 1979, Biochemistry.

Secretion of somatostatin by Saccharomyces cerevisiae. Correct proteolytic processing of pro-alpha-factor-somatostatin hybrids requires the products of the KEX2 and STE13 genes.

Y. Bourbonnais, D. Shields, D. Bolin, 1988, The Journal of biological chemistry.

The lipid kinase PI4KIIIβ preserves lysosomal identity

L. Santambrogio, A. Cuervo, F. Macian, 2012, The EMBO journal.

Cellular proteolytic systems, volume 15. Edited by Aaron J. Ciechanover and Alan L. Schwartz. Modern Cell Biology Series. New York: John Wiley and Sons. (1994). 233 pp. $84.95

D. Shields, 1995, Cell.

Tethering Function of the Caspase Cleavage Fragment of Golgi Protein p115 Promotes Apoptosis via a p53-dependent Pathway*

D. Shields, P. How, 2010, The Journal of Biological Chemistry.

Intracellular degradation of prohormone-chloramphenicol-acetyl-transferase chimeras in a pre-lysosomal compartment.

X. Mai, D. Shields, A. Danoff, 1993, European journal of biochemistry.

The Golgi Protein p115 Associates with γ-Tubulin and Plays a Role in Golgi Structure and Mitosis Progression*

S. Mukherjee, D. Shields, Andreea E. Radulescu, 2011, The Journal of Biological Chemistry.

Topogenic effect of positively charged N-terminal amino acid in ER translocation of yeast alpha-factor precursor.

J. Choe, D. Shields, K. Cheong, 1996, Cell structure and function.

Opposing Action of Casein Kinase 1 and Calcineurin in Nucleo-cytoplasmic Shuttling of Mammalian Translation Initiation Factor eIF6*

C. Chow, S. Mukherjee, Supratik Das, 2010, The Journal of Biological Chemistry.

Discontinuous translation of silk fibroin in a reticulocyte cell-free system and in intact silk gland cells.

P. Lizardi, V. Mahdavi, V Mahdavi, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Expression of anglerfish preprosomatostatin genes in mammalian cells: studies on the synthesis and post-translational processing of somatostatin precursors.

D. Shields, T. Warren, R. Green, 1985, Advances in experimental medicine and biology.

Secretory Vesicle Budding from the Trans-Golgi Network Is Mediated by Phosphatidic Acid Levels*

D. Shields, A. Siddhanta, 1998, The Journal of Biological Chemistry.

Fragmentation of the Golgi Apparatus: An Early Apoptotic Event Independent of the Cytoskeleton

S. Mukherjee, D. Shields, S. Leung, 2007, Traffic.

Phospholipase D in the Golgi apparatus.

A. Morris, C. Riebeling, D. Shields, 2009, Biochimica et biophysica acta.

Somatostatin-like immunoreactivity within neuritic plaques

R. Terry, D. Armstrong, D. Shields, 1985, Brain Research.

Nascent chicken ovalbumin contains the functional equivalent of a signal sequence

G. Blobel, V. Lingappa, S. Woo, 1978, The Journal of cell biology.

Transport of vesicular stomatitis virus G protein to the cell surface is signal mediated in polarized and nonpolarized cells

E. Rodriguez-Boulan, A. Müsch, D. Shields, 1996, The Journal of cell biology.

A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis

S. Mukherjee, D. Shields, L. Novikov, 2002, The Journal of cell biology.

A signal sequence domain essential for processing, but not import, of mitochondrial pre-ornithine carbamyl transferase

G. Shore, W. Sheffield, A. W. Bell, 1987, The Journal of cell biology.

Nuclear Import Is Required for the Pro-apoptotic Function of the Golgi Protein p115*♦

S. Mukherjee, D. Shields, 2009, Journal of Biological Chemistry.

Cell-free synthesis of angler fish preproinsulin: complete amino acid sequence of the signal peptide.

D. Shields, 1981, Biochemical and biophysical research communications.

Disease models provide insights into post-golgi protein trafficking, localization and processing.

P. Arvan, D. Shields, D. Shields, 1999, Current opinion in cell biology.

In vitro biosynthesis of somatostatin. Evidence for two distinct preprosomatostatin molecules.

D. Shields, 1980, The Journal of biological chemistry.

Translocation of preproinsulin across the endoplasmic reticulum membrane. The relationship between nascent polypeptide size and extent of signal recognition particle-mediated inhibition of protein synthesis.

D. Shields, M. Okun, 1992, The Journal of biological chemistry.

Prohormone processing in the trans-Golgi network: endoproteolytic cleavage of prosomatostatin and formation of nascent secretory vesicles in permeabilized cells

D. Shields, Huaxi Xu, 1993, The Journal of cell biology.

Phospholipase D Stimulates Release of Nascent Secretory Vesicles from the trans-Golgi Network

S. Hammond, M. Frohman, A. Morris, 1997, The Journal of cell biology.

Secretion of somatostatin by Saccharomyces cerevisiae. Correct processing of an alpha-factor-somatostatin hybrid.

M. Schaber, R. Kramer, D. Shields, 1986, The Journal of biological chemistry.

Intracellular trafficking and metabolic turnover of yeast prepro-α-factor-SRIF precursors in GH3 cells

S. Hong, D. Shields, M. Lee, 2002, Experimental & Molecular Medicine.