Li-xi Liao

发表

Small molecule induces mitochondrial fusion for neuroprotection via targeting CK2 without affecting its conventional kinase activity

Kewu Zeng, Lichao Wang, Q. Guo, 2021, Signal Transduction and Targeted Therapy.

Protosappanin B protects PC12 cells against oxygen-glucose deprivation-induced neuronal death by maintaining mitochondrial homeostasis via induction of ubiquitin-dependent p53 protein degradation.

Kewu Zeng, P. Tu, Yong Jiang, 2015, European journal of pharmacology.

Highly selective inhibition of IMPDH2 provides the basis of antineuroinflammation therapy

Kewu Zeng, Lichao Wang, P. Tu, 2017, Proceedings of the National Academy of Sciences.

Highly Selective Activation of Heat Shock Protein 70 by Allosteric Regulation Provides an Insight into Efficient Neuroinflammation Inhibition

Kewu Zeng, Lichao Wang, P. Tu, 2017, EBioMedicine.

Baoyuan decoction alleviates myocardial infarction through the regulation of metabolic dysfunction and the mitochondria-dependent caspase-9/3 pathway

Chun Li, Kewu Zeng, P. Tu, 2021, Acupuncture and Herbal Medicine.

Icariin Inhibits AGE-Induced Injury in PC12 Cells by Directly Targeting Apoptosis Regulator Bax

Kewu Zeng, P. Tu, Wei-Wei Li, 2019, Oxidative medicine and cellular longevity.

TDB protects vascular endothelial cells against oxygen-glucose deprivation/reperfusion-induced injury by targeting miR-34a to increase Bcl-2 expression

Kewu Zeng, P. Tu, Yong Jiang, 2016, Scientific Reports.

Deoxysappanone B, a homoisoflavone from the Chinese medicinal plant Caesalpinia sappan L., protects neurons from microglia-mediated inflammatory injuries via inhibition of IκB kinase (IKK)-NF-κB and p38/ERK MAPK pathways.

Kewu Zeng, P. Tu, Yong Jiang, 2015, European journal of pharmacology.

Caruifolin D from artemisia absinthium L. inhibits neuroinflammation via reactive oxygen species-dependent c-jun N-terminal kinase and protein kinase c/NF-κB signaling pathways.

Kewu Zeng, P. Tu, Yong Jiang, 2015, European journal of pharmacology.

Induction of hepatoma carcinoma cell apoptosis through activation of the JNK-nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-ROS self-driven death signal circuit.

Kewu Zeng, P. Tu, Yong Jiang, 2014, Cancer letters.

Pharmacologically targeting molecular motor promotes mitochondrial fission for anti-cancer

Kewu Zeng, Y. Qian, Qinghua Han, 2021, Acta pharmaceutica Sinica. B.

Allosteric regulation of protein 14-3-3ζ scaffold by small-molecule editing modulates histone H3 post-translational modifications

Qing Xia, Lichao Wang, P. Tu, 2020, Theranostics.

Schizandrin A Inhibits Microglia-Mediated Neuroninflammation through Inhibiting TRAF6-NF-κB and Jak2-Stat3 Signaling Pathways

P. Tu, Li-xi Liao, Fang-jiao Song, 2016, PloS one.

Natural small molecule FMHM inhibits lipopolysaccharide-induced inflammatory response by promoting TRAF6 degradation via K48-linked polyubiquitination

P. Tu, Yong Jiang, Jun Li, 2015, Scientific Reports.

Anti‐Neuroinflammatory Effect of MC13, a Novel Coumarin Compound From Condiment Murraya, Through Inhibiting Lipopolysaccharide‐Induced TRAF6‐TAK1‐NF‐κB, P38/ERK MAPKS and Jak2‐Stat1/Stat3 Pathways

P. Tu, Yong Jiang, H. Lv, 2015, Journal of cellular biochemistry.

Protosappanin A Maintains Neuronal Mitochondrial Homeostasis through Promoting Autophagic Degradation of Bax.

P. Tu, Jing-Kang Wang, Li-xi Liao, 2020, ACS chemical neuroscience.

Protosappanin A exerts anti-neuroinflammatory effect by inhibiting JAK2-STAT3 pathway in lipopolysaccharide-induced BV2 microglia.

Lichao Wang, P. Tu, Ming-bo Zhao, 2017, Chinese Journal of Natural Medicines.