C. Kochansky

发表

Metabolite Identification Using An Ion Mobility-Enhanced Data-Independent Acquisition Strategy and Automated Data Processing.

R. Mortishire-Smith, I. Zamora, M. Wrona, 2020, Rapid communications in mass spectrometry : RCM.

Differences in the pharmacokinetics of peroxisome proliferator-activated receptor agonists in genetically obese Zucker and sprague-dawley rats: implications of decreased glucuronidation in obese Zucker rats.

Mi-Sook Kim, R. Franklin, J. Strauss, 2004, Drug metabolism and disposition: the biological fate of chemicals.

SPECIES DIFFERENCES IN THE ELIMINATION OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST HIGHLIGHTED BY OXIDATIVE METABOLISM OF ITS ACYL GLUCURONIDE

Yuan-qing Xia, R. Franklin, C. Kochansky, 2005, Drug Metabolism and Disposition.

IDENTIFICATION AND METABOLISM OF A NOVEL DIHYDROHYDROXY-S-GLUTATHIONYL CONJUGATE OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONIST, MK-0767 [(±)-5-[(2,4-DIOXOTHIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[[(4-TRIFLUOROMETHYL) PHENYL]METHYL]BENZAMIDE], IN RATS

G. Doss, R. Franklin, Vijay Bhasker G Reddy, 2004, Drug Metabolism and Disposition.

Decreased liver triglyceride content in adult rats exposed to protein restriction during gestation and lactation: Roles of hepatic lipogenesis and lipid utilization in muscle and adipose tissue.

C. Kochansky, L. Pontiggia, Claudia Mendez-Garcia, 2019, Canadian journal of physiology and pharmacology.

Administration of Fenofibrate Markedly Elevates Fabp3 in Rat Liver and Plasma and Confounds Its Use as a Preclinical Biomarker of Cardiac and Muscle Toxicity.

Mike Lyman, Scott E. Fauty, K. Vlasakova, 2018, Lipids.

Determination of uremic toxins in biofluids: creatinine, creatine, uric acid and xanthines.

C. Kochansky, T. Strein, 2000, Journal of chromatography. B, Biomedical sciences and applications.

Differences in the metabolism and pharmacokinetics of two structurally similar PPAR agonists in dogs: involvement of taurine conjugation

M. S. Kim, Z. Wang, S. Wang, 2004, Xenobiotica; the fate of foreign compounds in biological systems.

Metabolism and pharmacokinetics of a dipeptidyl peptidase IV inhibitor in rats, dogs, and monkeys with selective carbamoyl glucuronidation of the primary amine in dogs.

David Q. Liu, C. Raab, P. Pearson, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Identification and Metabolism of a Novel Dihydrohydroxy-S-Glutathionyl Conjugate of a PPAR Agonist, MK-0767, in Rats

G. Doss, R. Franklin, B. Karanam, 2004 .

Software-aided approach to investigate peptide structure and metabolic susceptibility of amide bonds in peptide drugs based on high resolution mass spectrometry

I. Zamora, Fabien Fontaine, T. Radchenko, 2017, PloS one.

Electrophoretically mediated microanalysis with small molecules: The Jaffé method for creatinine carried out in a capillary tube

C. Kochansky, T. Strein, S. Kozioł, 2001, Electrophoresis.

Disposition of the Dipeptidyl Peptidase 4 Inhibitor Sitagliptin in Rats and Dogs

David Q. Liu, S. Xu, M. Beconi, 2007, Drug Metabolism and Disposition.

Discovery of potent, selective 4-fluoroproline-based thrombin inhibitors with improved metabolic stability.

Youwei Yan, J. Vacca, B. Wong, 2006, Bioorganic & medicinal chemistry.

Increasing the efficiency of in-capillary electrophoretically mediated microanalysis reactions via rapid polarity switching.

Christopher J Kochansky, Brandi D Sanders, Rachel L Slotcavage, 2005, Analytical chemistry.

Diminishing GSH-Adduct Formation of Tricyclic Diazepine-based Mutant IDH1 Inhibitors.

Matthew L. Maddess, Y. Liu, X. Fradera, 2022, ACS medicinal chemistry letters.

Simultaneous determination of MK-0767 and seven metabolites in rat urine using liquid chromatography/tandem mass spectrometry.

R. Franklin, R. Bakhtiar, C. Kochansky, 2004, Rapid communications in mass spectrometry : RCM.

Impact of pH on plasma protein binding in equilibrium dialysis.

K. Korzekwa, P. Lu, K. Koeplinger, 2008, Molecular pharmaceutics.

Endosomolytic bioreducible poly(amido amine disulfide) polymer conjugates for the in vivo systemic delivery of siRNA therapeutics.

B. Carr, K. Leander, L. Sepp-Lorenzino, 2013, Bioconjugate chemistry.

Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans

D. Dean, K. Lasseter, R. Franklin, 2006, Drug Metabolism and Disposition.

10-Hydroxy-7,8-dihydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-1,9(2H,6H)-diones: potent, orally bioavailable HIV-1 integrase strand-transfer inhibitors with activity against integrase mutants.

D. Hazuda, W. Schleif, L. Gabryelski, 2008, Bioorganic & medicinal chemistry letters.

The Role of P-glycoprotein in the Bioactivation of Raloxifene

Magang Shou, Jae H. Chang, Christopher J. Kochansky, 2006, Drug Metabolism and Disposition.

8-Hydroxy-3,4-dihydropyrrolo[1,2-a]pyrazine-1(2H)-one HIV-1 integrase inhibitors.

D. Hazuda, W. Schleif, L. Gabryelski, 2007, Bioorganic & medicinal chemistry letters.

Impact of pH on plasma protein binding in equilibrium dialysis.

K. Korzekwa, P. Lu, K. Koeplinger, 2008, Molecular pharmaceutics.

Mi-Sook Kim, R. Franklin, J. Strauss, 2004, Drug metabolism and disposition: the biological fate of chemicals.