S. Pignani

Tailoring the CRISPR system to transactivate coagulation gene promoters in normal and mutated contexts.

F. Bernardi, M. Pinotti, A. Branchini, 2019, Biochimica et biophysica acta. Gene regulatory mechanisms.

The carboxyl-terminal region of human coagulation factor X as a natural linker for fusion strategies.

F. Bernardi, M. Pinotti, A. Branchini, 2019, Thrombosis research.

The chaperone‐like sodium phenylbutyrate improves factor IX intracellular trafficking and activity impaired by the frequent p.R294Q mutation

P. Pinton, S. Marchi, F. Bernardi, 2018, Journal of thrombosis and haemostasis : JTH.

Deciphering the Ets-1/2-mediated transcriptional regulation of F8 gene identifies a minimal F8 promoter for hemophilia A gene therapy

M. Pinotti, D. Corà, R. Famà, 2020, Haematologica.

An engineered tale-transcription factor rescues transcription of factor VII impaired by promoter mutations and enhances its endogenous expression in hepatocytes

F. Bernardi, M. Pinotti, A. Branchini, 2016, Scientific Reports.