C. Narasimhan

发表

Identification and Functional Characterization of an Active-site Lysine in Mevalonate Kinase*

H. Miziorko, D. Potter, J. Wojnar, 1997, The Journal of Biological Chemistry.

Aggregation of biopharmaceuticals in human plasma and human serum

T. Arvinte, S. Gregory, H. Mach, 2013, mAbs.

An Intercompany Perspective on Compatibility and In-Use Stability Studies to Enable Administration of Biopharmaceutical Drug Products.

Elaine S E Stokes, Brittney J. Mills, Kevin Muthurania, 2021, Journal of pharmaceutical sciences.

Differential behavior of the two free sulfhydryl groups of human plasma fibronectin: Effects of environmental factors

C. Narasimhan, C. Lai, Ching-san Lai, 1991, Biopolymers.

Evidence that the two free sulfhydryl groups of plasma fibronectin are in different local environments. Saturation-recovery electron spin resonance study.

J. Yin, C. Narasimhan, C. Lai, 1989, Biophysical journal.

Effect of pegylation on self-association of IFN-α2b.

A. Ambrogelly, Mark A Haverick, Jason K. Cheung, 2014, Molecular pharmaceutics.

Overcoming Challenges With Intravenous Administration of an Investigational Protein Therapeutic.

Andrew Semple, Chakravarthy Narasimhan, Valentyn Antochshuk, 2017, Journal of pharmaceutical sciences.

Investigating Crystalline Protein Suspension Formulations of Pembrolizumab from MAS NMR Spectroscopy.

A. Cote, Yongchao Su, P. Reichert, 2022, Molecular pharmaceutics.

Molecular Properties of Cetiedil and Its Interactions with Human Erythrocytes

C. Narasimhan, 1987 .

Pseudomonas mevalonii 3-hydroxy-3-methylglutaryl-CoA lyase.

H. Miziorko, C. Narasimhan, 2000, Methods in enzymology.

Human 3-hydroxy-3-methylglutaryl-CoA lyase.

H. Miziorko, J. Roberts, C. Narasimhan, 2000, Methods in enzymology.

Pseudomonas mevalonii 3-hydroxy-3-methylglutaryl-CoA lyase: testing the function of the active site cysteine by site-directed mutagenesis.

H. Miziorko, J. Roberts, C. Narasimhan, 1995, Biochemistry.

Evaluation of Cysteine 266 of Human 3-Hydroxy-3-methylglutaryl-CoA Lyase as a Catalytic Residue (*)

H. Miziorko, C. Narasimhan, Jacqueline R. Roberts, 1995, The Journal of Biological Chemistry.

Pseudomonas mevalonii 3-hydroxy-3-methylglutaryl-CoA lyase: characterization of the isolated recombinant protein and investigation of the enzyme's cation requirements.

H. Miziorko, C. Narasimhan, 1992, Biochemistry.

Conformational changes of plasma fibronectin detected upon adsorption to solid substrates: a spin-label study.

C. Narasimhan, C. Lai, 1989, Biochemistry.

One free sulfhydryl group of plasma fibronectin becomes titratable upon binding of the protein to solid substrates.

A. Haas, C. Narasimhan, C. Lai, 1988, Biochemistry.

Estradiol-induced expression of genetic information: synthesis of phosvitin in birds.

P. Narayanan, M. Sopori, C. Narasimhan, 1974, Basic life sciences.

Pembrolizumab microgravity crystallization experimentation

T. Fischmann, G. Scapin, C. Strickland, 2019, npj Microgravity.

An Industry Perspective on Compatibility Assessment of Closed System Drug-Transfer Devices for Biologics.

Richard J. Galas, Ahmed Besheer, C. Zamiri, 2020, Journal of pharmaceutical sciences.

Avian 3-hydroxy-3-methylglutaryl-CoA synthase. Characterization of a recombinant cholesterogenic isozyme and demonstration of the requirement for a sulfhydryl functionality in formation of the acetyl-enzyme reaction intermediate.

H. Miziorko, C. Narasimhan, I. Misra, 1993, The Journal of biological chemistry.

Physicochemical stability of pembrolizumab admixture solution in normal saline intravenous infusion bag

C. Narasimhan, Prakash Sundaramurthi, S. Chadwick, 2019, Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.

An Intercompany Perspective on Practical Experiences of Predicting, Optimizing and Analyzing High Concentration Biologic Therapeutic Formulations.

Brittney J. Mills, P. Garidel, Shubhadra N. Singh, 2022, Journal of pharmaceutical sciences.

3-Hydroxy-3-methylglutaryl-CoA lyase: expression and isolation of the recombinant human enzyme and investigation of a mechanism for regulation of enzyme activity.

P. Hruz, H. Miziorko, G. Mitchell, 1994, The Journal of biological chemistry.

Improving monoclonal antibody selection and engineering using measurements of colloidal protein interactions.

Mohammed Shameem, Peter M Tessier, P. Tessier, 2014, Journal of pharmaceutical sciences.

High-dose monoclonal antibodies via the subcutaneous route: challenges and technical solutions, an industry perspective.

H. Mach, M. Shameem, C. Narasimhan, 2012, Therapeutic delivery.

Solution pH that minimizes self-association of three monoclonal antibodies is strongly dependent on ionic strength.

Mohammed Shameem, Peter M Tessier, A. Bhalla, 2012, Molecular pharmaceutics.

Reduced water exchange in sickle cell anemia red cells: a membrane abnormality.

L. Fung, C. Narasimhan, M. Westerman, 1989, Biochimica et biophysica acta.

P. mevalonii 3-hydroxy-3-methylglutaryl-CoA lyase: electron paramagnetic resonance investigation of the copper binding site.

H. Miziorko, W. Antholine, C. Narasimhan, 1994, Archives of Biochemistry and Biophysics.

3-Hydroxy-3-methylglutaryl coenzyme A lyase: affinity labeling of the Pseudomonas mevalonii enzyme and assignment of cysteine-237 to the active site.

P. Hruz, H. Miziorko, C. Narasimhan, 1992, Biochemistry.

Solution pH that minimizes self-association of three monoclonal antibodies is strongly dependent on ionic strength.

A. Bhalla, S. Blaisdell, P. Tessier, 2012, Molecular pharmaceutics.

An Intercompany Perspective on Biopharmaceutical Drug Product Robustness Studies.

Kapil Gupta, Dingjiang Liu, Christine Wurth, 2018, Journal of pharmaceutical sciences.

Crystalline Antibody‐Laden Alginate Particles: A Platform for Enabling High Concentration Subcutaneous Delivery of Antibodies

P. Hammond, P. Doyle, P. Reichert, 2023, Advanced Healthcare Materials.

Injectable hydrogel particles for amorphous solid formulation of biologics

P. Doyle, P. Reichert, C. Narasimhan, 2023, iScience.

Pembrolizumab microgravity crystallization experimentation

T. Fischmann, G. Scapin, C. Strickland, 2019, npj Microgravity.