S. Azhar

发表

Feedback inhibition of CREB signaling by p38 MAPK contributes to the negative regulation of steroidogenesis

W. Shen, Zhigang Guo, Qian Zhou, 2017, Reproductive Biology and Endocrinology.

Human granulosa cells use high density lipoprotein cholesterol for steroidogenesis.

L. Giudice, S. Medicherla, L. Tsai, 1998, The Journal of clinical endocrinology and metabolism.

Prolonged infusion of epinephrine down-regulates expression of the fatty acid synthase gene in adipocytes

B. Hoffman, J. H. Chin, S. Azhar, 1995, Endocrine.

Relationship between insulin resistance and partially oxidized LDL particles in healthy, nondiabetic volunteers.

G. Reaven, Mark M. Klebanov, F. Abbasi, 1998, Arteriosclerosis, thrombosis, and vascular biology.

Receptor-mediated gonadotropin action in ovary. Possible regulatory role of cell-surface sialic acid in gonadotropin interaction to purified bovine corpus luteum plasma membranes.

K. Menon, K. Menon, S. Azhar, 1981, European journal of biochemistry.

Receptor-mediated gonadotropin action in ovary. Differential effects of various gangliosides and cholera enterotoxin on 125I-choriogonadotropin binding, production of adenosine 3':5'-monophosphate and steroidogenesis in rat ovarian cells.

K. Menon, S. Azhar, 1979, European journal of biochemistry.

Role of gangliosides in gonadotropin and cholera enterotoxin stimulated steroidogenesis in isolated rat ovarian cells.

P. Fitzpatrick, K. Menon, S. Azhar, 1978, Biochemical and biophysical research communications.

Differential secretion of proteins and glycoproteins by livers of immature and adult rats. Effect of antimicrotubule drugs.

S. Azhar, E. Reaven, 1988, Biochemical pharmacology.

LH biosynthesis and secretion in rat anterior pituitary cell cultures: stimulation of LH glycosylation and secretion by GNRH and an agonistic analogue and blockade by an antagonistic analogue.

K. Menon, J. Reel, S. Azhar, 1978, Biochemical and biophysical research communications.

G. Reaven, E. Dall’aglio, S. Azhar, 1987, Journal of gerontology.

Effects of exercise training on the relationship between insulin binding and insulin-stimulated tyrosine kinase activity in rat skeletal muscle.

G. Reaven, C. Mondon, R. F. Santos, 1989, Metabolism: clinical and experimental.

Differential effects of aging on adrenocorticotropin receptors, adenosine 3'5'-monophosphate response, and corticosterone secretion in adrenocortical cells from Sprague-Dawley rats.

J. Ramachandran, M. Tsubokawa, S. Azhar, 1986, Endocrinology.

The Influence of Age on Steroidogenic Enzyme Activities of the Rat Adrenal Gland: Enhanced Expression of Cholesterol Side-Chain Cleavage Activity*

J. Butte, S. Azhar, P. Popplewell, 1987, Endocrinology.

Erythrocyte insulin receptor tyrosine kinase activity is increased in glyburide‐treated patients with type 2 diabetes in good glycaemic control

G. Reaven, B. Wajchenberg, R. F. Santos, 2000, Diabetes, obesity & metabolism.

Persistent Expression of Hepatitis C Virus Non-Structural Proteins Leads to Increased Autophagy and Mitochondrial Injury in Human Hepatoma Cells

S. Weinman, Ting-Ting Huang, V. Chu, 2011, PloS one.

Insulin resistance does not change the ratio of proinsulin to insulin in normal volunteers.

G. Reaven, F. Abbasi, Y. D. Chen, 1997, The Journal of clinical endocrinology and metabolism.

Lipid droplets and steroidogenic cells.

F. Kraemer, W. Shen, S. Azhar, 2016, Experimental cell research.

Cholesterol ester droplets and steroidogenesis

F. Kraemer, W. Shen, S. Azhar, 2013, Molecular and Cellular Endocrinology.

Estradiol regulation of sterol carrier protein-2 independent of cytochrome P450 side-chain cleavage expression in the rat corpus luteum.

I. Khan, G. Gibori, J. Orly, 1989, Endocrinology.

Placental-derived regulators and the complex control of luteal cell function.

I. Khan, G. Gibori, S. Nelson, 1988, Recent progress in hormone research.

A new HDL mimetic peptide that stimulates cellular cholesterol efflux with high efficiency greatly reduces atherosclerosis in mice

J. Johansson, V. Narayanaswami, Arti B. Patel, 2010, Journal of Lipid Research.

Peroxisome proliferator-activated receptor-α selective ligand reduces adiposity, improves insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient mice

Somesh D. Sharma, C. Bisgaier, S. Azhar, 2006, Molecular and Cellular Biochemistry.

SOD2 deficiency-induced oxidative stress attenuates steroidogenesis in mouse ovarian granulosa cells

Ting-Ting Huang, F. Kraemer, W. Shen, 2020, Molecular and Cellular Endocrinology.

Scavenger receptor class B, type 1 facilitates cellular fatty acid uptake.

F. Kraemer, W. Shen, S. Azhar, 2020, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Scavenger receptor B type 1: expression, molecular regulation, and cholesterol transport function

F. Kraemer, W. Shen, Shailendra Asthana, 2018, Journal of Lipid Research.

Scavenger receptor class B type I (SR-BI): a versatile receptor with multiple functions and actions.

F. Kraemer, W. Shen, Zhigang Hu, 2014, Metabolism: clinical and experimental.

Cholesterol uptake in adrenal and gonadal tissues: the SR-BI and 'selective' pathway connection.

S. Azhar, E. Reaven, S. Leers-sucheta, 2003, Frontiers in bioscience : a journal and virtual library.

Binding and Cross-linking Studies Show That Scavenger Receptor BI Interacts with Multiple Sites in Apolipoprotein A-I and Identify the Class A Amphipathic α-Helix as a Recognition Motif*

M. Connelly, G. Anantharamaiah, M. Phillips, 2000, The Journal of Biological Chemistry.

Simultaneous induction of an HDL receptor protein (SR-BI) and the selective uptake of HDL-cholesteryl esters in a physiologically relevant steroidogenic cell model.

S. Azhar, E. Reaven, A. Nomoto, 1998, Journal of lipid research.

Effects of antimicrotubule agents on phospholipid metabolism in rat hepatic subcellular membranes.

S. Azhar, E. Reaven, S. Hwang, 1985, Biochemical pharmacology.

Scavenger Receptor Class B, Type I, Mediates Selective Uptake of Low Density Lipoprotein Cholesteryl Ester*

M. Connelly, R. Temel, S. Swarnakar, 1999, The Journal of Biological Chemistry.

Insulin-secreting β-Cell Dysfunction Induced by Human Lipoproteins*

V. Mooser, J. Haefliger, G. Waeber, 2003, The Journal of Biological Chemistry.

Plasma Leptin Concentrations Do Not Appear to Decrease Insulin-Mediated Glucose Disposal or Glucose-Stimulated Insulin Secretion in Women With Normal Glucose Tolerance

G. Reaven, Mark M. Klebanov, Pei-Wen Wang, 1998, Diabetes.

Effect of masoprocol on glucose transport and lipolysis by isolated rat adipocytes.

G. Reaven, M. Gowri, S. Azhar, 1999, Metabolism: clinical and experimental.

Lactate Production and Pyruvate Dehydrogenase Activity in Fat and Skeletal Muscle From Diabetic Rats

G. Reaven, C. Mondon, C. Hollenbeck, 1992, Diabetes.

Abnormal insulin metabolism by specific organs from rats with spontaneous hypertension.

G. Reaven, R. Rabkin, C. Mondon, 1989, The American journal of physiology.

Structure and function changes in rat adrenal glands during aging.

J. Ramachandran, S. Azhar, E. Reaven, 1988, The American journal of physiology.

Insulin resistance in older rats.

G. Reaven, C. Mondon, C. Dolkas, 1984, The American journal of physiology.

Masoprocol lowers blood pressure in rats with fructose-induced hypertension.

G. Reaven, M. Gowri, S. Azhar, 1999, American journal of hypertension.

Evidence of an age-related decline in mitochondrial glycerophosphate dehydrogenase activity of isolated rat islets.

G. Reaven, S. Azhar, E. Reaven, 1983, Metabolism: clinical and experimental.

Functional homogeneity of pancreatic islets of aging rats.

G. Reaven, S. Azhar, E. Reaven, 1982, Metabolism: clinical and experimental.

Resistance to Insulin-Stimulated Glucose Uptake in Adipocytes Isolated From Spontaneously Hypertensive Rats

G. Reaven, B. Hoffman, S. Azhar, 1989, Diabetes.

Differences in insulin action as a function of original anatomical site of newly differentiated adipocytes obtained in primary culture.

G. Reaven, C. Sztalryd, S. Azhar, 1991, The Journal of clinical investigation.

Peroxisome proliferator-activated receptor-alpha selective ligand reduces adiposity, improves insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient mice.

Somesh D. Sharma, C. Bisgaier, S. Azhar, 2006, Molecular and cellular biochemistry.

Can changes in plasma insulin concentration explain the variability in leptin response to weight loss in obese women with normal glucose tolerance?

G. Reaven, F. Abbasi, P. Schaaf, 1999, The Journal of clinical endocrinology and metabolism.

Alterations in glucose and protein metabolism in animals subjected to simulated microgravity.

G. Reaven, C. Mondon, K. Rodnick, 1992, Advances in space research : the official journal of the Committee on Space Research.

Expression of the major isoenzyme of protein kinase-C in skeletal muscle, nPKC theta, varies with muscle type and in response to fructose-induced insulin resistance.

G. Reaven, R. Donnelly, S. Azhar, 1994, Endocrinology.

Nordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways.

F. Kraemer, W. Shen, S. Azhar, 2013, American journal of physiology. Gastrointestinal and liver physiology.

Characterization of insulin receptor kinase activity and autophosphorylation in different skeletal muscle types.

G. Reaven, J. Butte, C. Mondon, 1991, The American journal of physiology.

Effects of insulin on carbohydrate and protein metabolism in voluntary running rats.

G. Reaven, C. Mondon, K. Rodnick, 1990, The American journal of physiology.

Changes in insulin receptor tyrosine kinase activity associated with metformin treatment of type 2 diabetes.

G. Reaven, R. F. Santos, R. Nomizo, 1995, Diabete & metabolisme.

Insulin-receptor tyrosine kinase activity is decreased in erythrocytes from non-obese patients with NIDDM.

B. Wajchenberg, R. F. Santos, S. Azhar, 1994, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Suppression of steroidogenesis and activator protein-1 transcription factor activity in rat adrenals by vitamin E deficiency-induced chronic oxidative stress.

S. Azhar, P. Abidi, S. Leers-sucheta, 2004, The Journal of nutritional biochemistry.

Insulin-secreting beta-cell dysfunction induced by human lipoproteins.

V. Mooser, J. Haefliger, G. Waeber, 2003, The Journal of biological chemistry.

High-fructose feeding promotes accelerated degradation of hepatic LDL receptor and hypercholesterolemia in hamsters via elevated circulating PCSK9 levels.

N. Seidah, Jingwen Liu, A. B. Singh, 2015, Atherosclerosis.

Effect of metformin on insulin-stimulated tyrosine kinase activity of erythrocytes from obese women with normal glucose tolerance.

G. Reaven, B. Wajchenberg, R. F. Santos, 1997, Diabetes & metabolism.

Multiple inhibitory actions of luteinizing hormone-releasing hormone agonist on luteinizing hormone/human chorionic gonadotropin receptor-mediated ovarian responses.

K. Menon, P. V. Reddy, S. Azhar, 1980, Endocrinology.

F. Kraemer, W. Shen, Masami Ueno, 2013, PloS one.

Scavenger receptor class B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells.

M. Krieger, B. Trigatti, R. Demattos, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Why does insulin resistance develop during maturation?

G. Reaven, C. Mondon, S. Azhar, 1993, Journal of gerontology.

Utilization of cholesterol-rich lipoproteins by perfused rat adrenals.

S. Azhar, E. Reaven, D. Stewart, 1989, Journal of lipid research.

Differences in uptake of high-density lipoproteins by rat adrenals using in vivo vs. in situ perfusion techniques.

S. Azhar, E. Reaven, 1989, Biochimica et biophysica acta.

Aging alters the functional expression of enzymatic and non-enzymatic anti-oxidant defense systems in testicular rat Leydig cells

S. Azhar, S. Leers-sucheta, Luchuan Cao, 2004, The Journal of Steroid Biochemistry and Molecular Biology.

Age-dependent modulation of NF-κB expression in rat adrenal gland

S. Azhar, S. Leers-sucheta, Rajeshwari Medicherla, 2002, Mechanisms of Ageing and Development.

Impaired activation of AP-1 and altered expression of constituent proteins in rat adrenal during ageing

S. Azhar, S. Leers-sucheta, Rajeshwari Medicherla, 2001, Mechanisms of Ageing and Development.

Characterization of apoB, E receptor function in the luteinized ovary.

L. Tsai, A. Cooper, S. Azhar, 1988, Journal of lipid research.

Chinese Hamster Ovary Cells Expressing a Cell Surface-anchored Form of Hepatic Lipase

M. Komaromy, A. Cooper, S. Azhar, 1996, The Journal of Biological Chemistry.

Evidence for Surface Entrapment of Cholesterol‐Rich Lipoproteins in Luteinized Ovary

J. Boyles, S. Azhar, E. Reaven, 1988, Arteriosclerosis.

Regulation of luteal cell lipoprotein receptors, sterol contents, and steroidogenesis by estradiol in the pregnant rat.

G. Reaven, I. Khan, G. Gibori, 1984, Endocrinology.

ACTH Regulation of Adrenal SR-B1

F. Kraemer, W. Shen, S. Azhar, 2016, Front. Endocrinol..

Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones

W. Shen, Zhonghua Zhang, S. Azhar, 2010, Nutrition & metabolism.

Consequences of over-expression of rat Scavenger Receptor, SR-BI, in an adrenal cell model

S. Azhar, E. Reaven, A. Nomoto, 2006, Nutrition & metabolism.

Dimerization of the scavenger receptor class B type I: formation, function, and localization in diverse cells and tissues.

S. Azhar, E. Reaven, A. Nomoto, 2004, Journal of lipid research.

Lipoprotein enhancement of ovarian theca-interstitial cell steroidogenesis: relative contribution of scavenger receptor class B (type I) and adenosine 5'-triphosphate- binding cassette (type A1) transporter in high-density lipoprotein-cholesterol transport and androgen synthesis.

K. Menon, Qian Wu, S. Azhar, 2003, Endocrinology.

Expression of scavenger receptor class B type 1 (SR-BI) promotes microvillar channel formation and selective cholesteryl ester transport in a heterologous reconstituted system.

S. Azhar, E. Reaven, A. Nomoto, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Angiotensin II promotes selective uptake of high density lipoprotein cholesterol esters in bovine adrenal glomerulosa and human adrenocortical carcinoma cells through induction of scavenger receptor class B type I.

N. Demaurex, N. Cherradi, A. Capponi, 2001, Endocrinology.

Expression and microvillar localization of scavenger receptor class B, type I (SR-BI) and selective cholesteryl ester uptake in Leydig cells from rat testis.

S. Azhar, E. Reaven, A. Nomoto, 2000, Journal of lipid research.

The selective pathway and a high-density lipoprotein receptor (SR-BI) in ovarian granulosa cells of the mouse.

R. Temel, D. Williams, D. R. van der Westhuyzen, 1999, Biochimica et biophysica acta.

Comparison of Class B Scavenger Receptors, CD36 and Scavenger Receptor BI (SR-BI), Shows That Both Receptors Mediate High Density Lipoprotein-Cholesteryl Ester Selective Uptake but SR-BI Exhibits a Unique Enhancement of Cholesteryl Ester Uptake*

Seth M. Klein, M. Connelly, N. Abumrad, 1999, The Journal of Biological Chemistry.

Upregulation of selective cholesteryl ester uptake pathway in mice with deletion of low‐density lipoprotein receptor function

S. Medicherla, S. Azhar, E. Reaven, 1999, Journal of cellular physiology.

Expression and microvillar localization of scavenger receptor, class B, type I (a high density lipoprotein receptor) in luteinized and hormone-desensitized rat ovarian models.

R. Temel, D. Williams, S. Azhar, 1998, Endocrinology.

Intracellular Events in the “Selective” Transport of Lipoprotein-derived Cholesteryl Esters*

S. Azhar, E. Reaven, Louisa Tsai, 1996, The Journal of Biological Chemistry.

Morphological evidence that high density lipoproteins are not internalized by steroid-producing cells during in situ organ perfusion.

Y. D. Chen, S. Azhar, E. Reaven, 1984, The Journal of clinical investigation.

Cholesterol uptake by the 'selective' pathway of ovarian granulosa cells: early intracellular events.

L. Tsai, S. Azhar, E. Reaven, 1995, Journal of lipid research.

Keratin 8 absence down-regulates colonocyte HMGCS2 and modulates colonic ketogenesis and energy metabolism

M. Omary, D. Toivola, Lina E Fortelius, 2015, Molecular biology of the cell.

Evidence that age‐related changes in p38 MAP kinase contribute to the decreased steroid production by the adrenocortical cells from old rats

Jiahuai Han, S. Azhar, P. Abidi, 2008, Aging cell.

Fat-specific protein 27 modulates nuclear factor of activated T cells 5 and the cellular response to stress[S]

A. Greenberg, F. Kraemer, W. Shen, 2013, Journal of Lipid Research.

LDL and cAMP cooperate to regulate the functional expression of the LRP in rat ovarian granulosa cells Published, JLR Papers in Press, August 23, 2006.

L. Fong, W. Shen, S. Medicherla, 2006, Journal of Lipid Research.

Isoproterenol decreases LDL receptor expression in rat adipose cells: activation of cyclic AMP-dependent proteolysis.

M. Komaromy, S. Patel, F. Kraemer, 1996, Journal of lipid research.

SNAREs and cholesterol movement for steroidogenesis

F. Kraemer, W. Shen, S. Azhar, 2017, Molecular and Cellular Endocrinology.

Receptor mediated gonadotropin action in gonadal tissues: relationship between blood cholesterol levels and gonadotropin stimulated steroidogenesis in isolated rat Leydig and luteal cells.

K. Menon, S. Azhar, 1982, Journal of steroid biochemistry.

Receptor-mediated gonadotropin action in the ovary. Demonstration of acute dependence of rat luteal cells on exogenously supplied steroid precursor (sterols) for gonadotropin-induced steroidogenesis.

K. Menon, S. Azhar, M. Menon, 1981, Biochimica et biophysica acta.

Enhanced expression of granulosa cell low density lipoprotein receptor activity in response to in vitro culture conditions

M. Philip, L. Tsai, A. Cooper, 1994, Journal of cellular physiology.

Secretion and Action of Steroids in the Luteal Cell

G. Gibori, M. Rao, R. Sridaran, 1984 .

Microvillar channels: a unique plasma membrane compartment for concentrating lipoproteins on the surface of rat adrenal cortical cells.

S. Azhar, E. Reaven, M. Spicher, 1989, Journal of Lipid Research.

Hormone-sensitive lipase is required for high-density lipoprotein cholesteryl ester-supported adrenal steroidogenesis.

F. Kraemer, S. Ishibashi, W. Shen, 2004, Molecular endocrinology.

Uptake of low density lipoproteins by rat tissues. Special emphasis on the luteinized ovary.

C. Mondon, Y. D. Chen, S. Azhar, 1986, The Journal of clinical investigation.

Removal of chylomicron remnants in transgenic mice overexpressing normal and membrane-anchored hepatic lipase Published, JLR Papers in Press, November 1, 2004. DOI 10.1194/jlr.M400184-JLR200

Sungshin Y. Choi, Sung-Joon Lee, A. Cooper, 2005, Journal of Lipid Research.

Generation of antibodies against a human lipoprotein lipase fusion protein.

M. Komaromy, F. Kraemer, P. Maheux, 1995, Life sciences.

Effect of TCF7L2 polymorphism on pancreatic hormones after exenatide in type 2 diabetes

M. da Silva, S. Azhar, R. F. dos Santos, 2019, Diabetology & Metabolic Syndrome.

Interaction of Hormone-sensitive Lipase with Steroidogeneic Acute Regulatory Protein

F. Kraemer, W. Shen, V. Natu, 2003, Journal of Biological Chemistry.

Adrenal Neutral Cholesteryl Ester Hydrolase: Identification, Subcellular Distribution, and Sex Differences.

F. Kraemer, S. Ishibashi, W. Shen, 2002, Endocrinology.

Uptake and utilization of lipoprotein cholesteryl esters by rat granulosa cells.

L. Tsai, S. Azhar, E. Reaven, 1990, Biochimica et biophysica acta.

Evidence that insulin deficiency in the rat has disparate effects on fructose 2,6-bisphosphate levels in muscle and liver.

G. Reaven, E. Dall’aglio, S. Azhar, 1986, Endocrinology.

Luteal cell 3-hydroxy-3-methylglutaryl coenzyme-A reductase activity and cholesterol metabolism throughout pregnancy in the rat.

I. Khan, G. Gibori, Y. D. Chen, 1988, Endocrinology.

The LDL receptor is not necessary for acute adrenal steroidogenesis in mouse adrenocortical cells.

F. Kraemer, S. Ishibashi, W. Shen, 2007, American journal of physiology. Endocrinology and metabolism.

LH/hCG-stimulated androgen production and selective HDL-cholesterol transport are inhibited by a dominant-negative CREB construct in primary cultures of rat theca-interstitial cells

K. Menon, H. Peegel, R. Towns, 2005, Endocrine.

Differential Regulation of Steroid Hormone Biosynthesis in R2C and MA-10 Leydig Tumor Cells: Role of SR-B1-Mediated Selective Cholesteryl Ester Transport1

Y. Jo, D. Stocco, W. Miller, 2003, Biology of reproduction.

Effect of age on cholesterol uptake and utilization by rat adrenals: I. Internalization of lipoprotein-derived cholesteryl esters

S. Azhar, E. Reaven, 1994, Mechanisms of Ageing and Development.

S. Azhar, E. Reaven, Chin-Sheng Liao, 1993, The Journal of Steroid Biochemistry and Molecular Biology.

Cholesterol and Age-Related Changes in Adrenal Steroidogenesis

S. Azhar, E. Reaven, P. Popplewell, 1990 .

Opposite effect of human chorionic gonadotropin on placental and ovarian synthesis of androstenedione.

G. Gibori, D. Johnson, S. Azhar, 1987, Endocrinology.

The effect of colchicine on cholesterol processing by the progesterone-producing cells of the luteinized ovary.

Y. D. Chen, S. Azhar, E. Reaven, 1986, Journal of steroid biochemistry.

Regulation of luteal cell 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by estradiol.

Ida, G. Reaven, I. Khan, 1985, Biology of reproduction.

Gonadotropin modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in desensitized luteinized rat ovary.

G. Reaven, Y. D. Chen, S. Azhar, 1984, Biochemistry.

The role of miRNAs in regulating adrenal/gonadal steroidogenesis.

F. Kraemer, W. Shen, Dachuan Dong, 2020, Journal of molecular endocrinology.

Arachidonic acid downregulates acyl-CoA synthetase 4 expression by promoting its ubiquitination and proteasomal degradation[S]

Jingwen Liu, D. Stafforini, A. B. Singh, 2014, Journal of Lipid Research.

Keratin 8 Phosphorylation by p38 Kinase Regulates Cellular Keratin Filament Reorganization

M. Omary, N. Ku, S. Azhar, 2002, The Journal of Biological Chemistry.

Expression of multiple isoenzymes of protein kinase C in airway smooth muscle.

M. Omary, R. Donnelly, J. Black, 1995, American journal of respiratory cell and molecular biology.

Expression, Purification and Characterization of the Rat Luteal 20α-Hydroxysteroid Dehydrogenase1.

G. Gibori, L. Zhong, J. Mao, 1997, Endocrinology.

Expression, Purification and Characterization of the Rat Luteal 20 (cid:97) -Hydroxysteroid Dehydrogenase*

G. Gibori, L. Zhong, J. Mao, 1996 .

Adenosine-3':5'-monophosphate-dependent and plasma-membrane-associated protein kinase from bovine corpus luteum. Solubilization and properties of solubilized enzyme.

K. Menon, S. Azhar, Sialmari Azhar, 1975, European journal of biochemistry.

Adenosine 3',5'-monophosphate dependent phosphorylation of ribosomes and ribosomal subunits from bovine corpus luteum

K. Menon, S. Azhar, 1975 .

Evidence that danazol inhibits gonadotropin-induced ovarian steroidogenesis at a point distal to gonadotropin-receptor interaction and adenosine 3',5' cyclic monophosphate formation.

K. Menon, S. Azhar, M. Menon, 1980, American journal of obstetrics and gynecology.

Gonadotropin receptors in plasma membranes of bovine corpus luteum. II. Role of membrane phospholipids.

K. Menon, S. Azhar, A. Hajra, 1976, The Journal of biological chemistry.

Enhanced Hepatic apoA-I Secretion and Peripheral Efflux of Cholesterol and Phospholipid in CD36 Null Mice

F. Nassir, N. Abumrad, B. Finck, 2010, PloS one.

Evidence for the involvement of an energy-dependent process in gonadotropin-releasing hormone-stimulated luteinizing hormone release by rat anterior pituitary.

K. Menon, K. Sen, S. Azhar, 1979, Endocrinology.

Hormonal regulation of adrenal microvillar channel formation.

S. Azhar, E. Reaven, A. Nomoto, 2002, Journal of lipid research.

Down-regulation of steroidogenic acute regulatory (StAR) protein in rat Leydig cells: implications for regulation of testosterone production during aging

D. Stocco, S. Azhar, S. Leers-sucheta, 1999, Mechanisms of Ageing and Development.

Ablation of vimentin results in defective steroidogenesis.

F. Kraemer, W. Shen, S. K. Zaidi, 2012, Endocrinology.

Effect of various hepatic membrane fractions on microtubule assembly- with special emphasis on the role of membrane phospholipids

S. Azhar, E. Reaven, 1981, The Journal of cell biology.

Amelioration of streptozotocin-induced diabetes in the rat by exercise-training: role of muscle glycogenolytic and glycolytic enzyme activity.

G. Reaven, S. Azhar, H. Chang, 2008, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Ca2+-activated and phospholipid- dependent hepatic protein kinase (protein kinase C): A standardized method for the determination of enzyme activity

S. Azhar, 1991 .

Sedimentation behavior of solubilized gonadotropin receptor from plasma membranes of bovine corpus luteum.

K. Menon, S. Azhar, V. Thambyrajah, 1976, Biochimica et biophysica acta.

Solubilization and characterization of phosphoprotein phosphatase(s) from bovine corpus-luteum plasma membranes.

K. Menon, S. Azhar, Salman Azhar, 1975, European journal of biochemistry.

Cyclic adenosine 3′, 5′ — monophosphate and luteinizing hormone stimulated protein kinase from bovine corpus luteum: Evidence for activation through separate mechanisms

K. Menon, S. Azhar, 1975, FEBS letters.

Effect of antimicrotubule agents on microtubules and steroidogenesis in luteal cells.

S. Azhar, E. Reaven, 1982, The American journal of physiology.

Regulation of cyclic adenosine 3', 5' -mono-phosphate dependent protein kinase of rat ovarian cells by luteinizing hormone and human chorionic gonadotropin.

K. Menon, S. Azhar, M. R. Clark, 1976, Endocrine research communications.

Alteration of the adrenal antioxidant defense system during aging in rats.

S. Azhar, E. Reaven, L. Cao, 1995, The Journal of clinical investigation.

Epigenetic BET reader inhibitor apabetalone (RVX-208) counters proinflammatory aortic gene expression in a diet induced obesity mouse model and in human endothelial cells.

S. Wasiak, N. Wong, B. Rakai, 2021, Atherosclerosis.

Protein kinase C catalyzed phosphorylation of sterol carrier protein 2.

G. Gibori, S. Azhar, M. McLean, 1989, Endocrinology.

Receptor-mediated gonadotropin action in the ovary. Rat luteal cells preferentially utilize and are acutely dependent upon the plasma lipoprotein-supplied sterols in gonadotropin-stimulated steroid production.

K. Menon, S. Azhar, Salman AzharS, 1981, The Journal of biological chemistry.

Compositional changes during the germination of cicer arietinum

A. Srivastava, S. Azhar, C. Murti, 1972 .

Stimulation of RNA synthesis in Cicer arietinum seedlings by cyclic 3′:5′ adenosine monophosphate

A. Srivastava, S. Azhar, C. Murti, 1973, FEBS letters.

Cyclic Nucleotide Phosphodiesterases from Rat Anterior Pituitary

K. Menon, S. Azhar, 1977 .

Effect of indole-3-acetic acid on the synthesis of cyclic 3'-5' adenosine phosphate by Bengal gram seeds.

S. Azhar, C. Murti, 1971, Biochemical and biophysical research communications.

MicroRNA-122: a new player in the negative regulation of LH receptor expression by the LH receptor mRNA binding protein (LRBP).

S. Azhar, 2013, Endocrinology.

Receptor-mediated gonadotropin action in the ovary. Desensitization of gonadotropin binding sites, activation of adenosine 3':5'-cyclic monophosphate-dependent protein kinase(s), and regulation of steroidogenesis in rat ovary.

K. Menon, K. Sen, S. Azhar, 1979, The Journal of biological chemistry.

The Apolipoprotein E-dependent Low Density Lipoprotein Cholesteryl Ester Selective Uptake Pathway in Murine Adrenocortical Cells Involves Chondroitin Sulfate Proteoglycans and an α2-Macroglobulin Receptor*

D. Strickland, J. Beers, S. Swarnakar, 2001, The Journal of Biological Chemistry.

Effect of okadaic acid on utilization of lipoprotein-derived cholesteryl esters by rat steroidogenic cells.

L. Tsai, S. Azhar, E. Reaven, 1994, Journal of lipid research.

Effect of antimicrotubule agents on terminal glycosyltransferases and other enzymes associated with rat liver subcellular fractions.

S. Azhar, E. Reaven, S. Hwang, 1983, The Biochemical journal.

Oxidative stress-induced inhibition of adrenal steroidogenesis requires participation of p38 mitogen-activated protein kinase signaling pathway.

Jiahuai Han, W. Shen, S. Azhar, 2008, The Journal of endocrinology.

Oxidative stress-induced inhibition of adrenal steroidogenesis requires participation of p 38 mitogen-activated protein kinase signaling pathway

Jiahuai Han, W. Shen, S. Azhar, 2008 .

SNARE-Mediated Cholesterol Movement to Mitochondria Supports Steroidogenesis in Rodent Cells.

F. Kraemer, W. Shen, S. Azhar, 2016, Molecular endocrinology.

PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease. Part I: PPAR-α.

F. Kraemer, W. Shen, S. Azhar, 2017, Future cardiology.

Impact of Aging on Steroid Hormone Biosynthesis and Secretion

W. Shen, S. K. Zaidi, S. Azhar, 2013 .

Post-transcriptional and Post-translational Regulation of Steroidogenesis

F. Kraemer, W. Shen, Zhigang Hu, 2016 .

Hormonal Regulation of MicroRNA Expression in Steroid Producing Cells of the Ovary, Testis and Adrenal Gland

F. Kraemer, W. Shen, Zhigang Hu, 2013, PloS one.

MicroRNAs 125a and 455 Repress Lipoprotein-Supported Steroidogenesis by Targeting Scavenger Receptor Class B Type I in Steroidogenic Cells

F. Kraemer, W. Shen, Zhigang Hu, 2012, Molecular and Cellular Biology.

Targeting Scavenger Receptor Class B, Type I (SR-BI) in Steroidogenic Cells*

F. Kraemer, W. Shen, Zhigang Hu, 2012 .

Dysregulation of microRNA-125a contributes to obesity-associated insulin resistance and dysregulates lipid metabolism in mice.

W. Shen, Zhigang Guo, Meina Wang, 2020, Biochimica et biophysica acta. Molecular and cell biology of lipids.

PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease. Part II: PPAR-β/δ and PPAR-γ.

F. Kraemer, W. Shen, S. Azhar, 2017, Future cardiology.

Regulation of adrenal and ovarian steroidogenesis by miR-132.

F. Kraemer, W. Shen, Zhigang Hu, 2017, Journal of molecular endocrinology.

Calcium-activated, phospholipid-dependent protein kinases from rat liver: subcellular distribution, purification, and characterization of multiple forms.

J. Butte, S. Azhar, E. Reaven, 1987, Biochemistry.

Cell-Specific Polymorphism and Hormonal Regulation of DNA Methylation in Scavenger Receptor Class B, Type I.

Zhigang Guo, Meina Wang, Zhihui Kuang, 2016, DNA and cell biology.

Regulation of Leydig Cell Cholesterol Metabolism

S. Azhar, E. Reaven, 2007 .

Scavenger receptor class BI and selective cholesteryl ester uptake: partners in the regulation of steroidogenesis

S. Azhar, E. Reaven, 2002, Molecular and Cellular Endocrinology.

The influence of estradiol on cholesterol processing by the corpus luteum.

I. Khan, G. Gibori, S. Azhar, 1989, Biology of reproduction.

Interaction of lipoproteins with isolated ovary plasma membranes.

S. Azhar, E. Reaven, X. Shi, 1990, The Journal of biological chemistry.

Differential regulation of PGC-1α expression in rat liver and skeletal muscle in response to voluntary running

D. M. Rocha, B. Wajchenberg, S. Azhar, 2010, Nutrition & metabolism.

A novel BET bromodomain inhibitor, RVX-208, shows reduction of atherosclerosis in hyperlipidemic ApoE deficient mice.

P. Young, N. Wong, K. McLure, 2014, Atherosclerosis.

Receptor mediated gonadotropin action in the ovary. Modulation of progesterone response in isolated rat ovarian cells by gonadotrophin, cholera enterotoxin and cyclic nucleotides: requirement for RNA and protein synthesis.

K. Menon, S. Azhar, M. Menon, 1980, Acta endocrinologica.

Differential roles of cysteine residues in the cellular trafficking, dimerization, and function of the high-density lipoprotein receptor, SR-BI.

W. Shen, Zhonghua Zhang, S. Azhar, 2011, Biochemistry.

Microarray analysis of gene expression in liver, adipose tissue and skeletal muscle in response to chronic dietary administration of NDGA to high-fructose fed dyslipidemic rats

F. Kraemer, W. Shen, S. Azhar, 2016, Nutrition & Metabolism.

Prolonged activation of alpha 1 adrenoceptors induces down-regulation of protein kinase C in vascular smooth muscle.

B. Hoffman, S. Azhar, Z. Hu, 1992, Journal of Cardiovascular Pharmacology.

Differential actions of gangliosides on gonadotropin and cholera enterotoxin stimulated adenosine3':5' cyclic monophosphate dependent protein kinase in isolated rat ovarian cells.

K. Menon, S. Azhar, 1978, Biochemical and biophysical research communications.

Relationship between insulin-mediated glucose disposal and regulation of plasma and adipose tissue lipoprotein lipase

G. Reaven, P. Kern, P. Maheux, 1997, Diabetologia.

Molecular changes in hepatic metabolism in ZDSD rats-A new polygenic rodent model of obesity, metabolic syndrome, and diabetes.

F. Kraemer, W. Shen, R. Peterson, 2020, Biochimica et biophysica acta. Molecular basis of disease.

Peroxisome proliferator-activated receptors, metabolic syndrome and cardiovascular disease.

Salman Azhar, S. Azhar, 2010, Future cardiology.

Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis

F. Kraemer, W. Shen, S. Azhar, 2015, PloS one.

NHERF1 and NHERF2 regulation of SR-B1 stability via ubiquitination and proteasome degradation.

Lingfeng He, W. Shen, Zhigang Guo, 2017, Biochemical and biophysical research communications.

A Novel Role of Salt-Inducible Kinase 1 (SIK1) in the Post-Translational Regulation of Scavenger Receptor Class B Type 1 Activity.

F. Kraemer, W. Shen, Zhigang Hu, 2015, Biochemistry.

Calcium-activated phospholipid-dependent protein kinases from rat liver: characterization of purified isoenzymic forms.

J. Butte, S. Azhar, E. Reaven, 1989, The International journal of biochemistry.

Identification of isoenzymic forms of hepatic Ca2+-activated-phospholipid-dependent protein kinase in various animal models.

J. Butte, S. Azhar, E. Reaven, 1988, Biochemical and biophysical research communications.

Receptor-mediated gonadotropin action in the ovary. Inhibitory actions of concanavalin A and wheat-germ agglutinin on gonadotropin-stimulated cyclic AMP and progesterone responses in ovarian cells.

K. Menon, S. Azhar, 1981, The Biochemical journal.

Reversal of High dietary fructose-induced PPARα suppression by oral administration of lipoxygenase/cyclooxygenase inhibitors

S. Azhar, Glen L. Kelley, 2005, Nutrition & metabolism.

A possible role of cyclic 3′,5′-adenosine monophosphate in the germination of Cicer arietinum seeds

S. Azhar, C. Murti, A. Srivastava, 1975 .

Activation of adenyl cyclase in the early phase of germination

A. Srivastava, S. Azhar, C. Murti, 1974, FEBS Letters.

Inhibition of germination in cicer arietinum

A. Srivastava, S. Azhar, C. Murti, 1972 .

SR-B1: A Unique Multifunctional Receptor for Cholesterol Influx and Efflux.

F. Kraemer, W. Shen, S. Azhar, 2018, Annual review of physiology.

Plasma membrane cholesterol trafficking in steroidogenesis

F. Kraemer, W. Shen, Dachuan Dong, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Inactivation of endothelial derived relaxing factor by oxidized lipoproteins.

B. Hoffman, J. H. Chin, S. Azhar, 1992, The Journal of clinical investigation.

p38 MAPK regulates steroidogenesis through transcriptional repression of STAR gene.

Jiahuai Han, F. Kraemer, W. Shen, 2014, Journal of molecular endocrinology.

Selective Uptake of Low Density Lipoprotein-Cholesteryl Ester Is Enhanced by Inducible Apolipoprotein E Expression in Cultured Mouse Adrenocortical Cells*

M. Reyland, S. Swarnakar, S. Azhar, 1998, The Journal of Biological Chemistry.

Effect of age on cholesterol uptake and utilization by rat adrenals: II. Lipoproteins from young and old rats

S. Azhar, E. Reaven, Luchuan Cao, 1994, Mechanisms of Ageing and Development.

Okadaic acid interferes with lipoprotein-supported corticosterone production in adrenal cells.

L. Tsai, S. Azhar, E. Reaven, 1991, Biochemical and biophysical research communications.

Cultivation of rat granulosa cells in a serum-free chemically defined medium--a useful model to study lipoprotein metabolism.

L. Tsai, S. Azhar, E. Reaven, 1988, Biochimica et biophysica acta.

The Proteome of Cholesteryl-Ester-Enriched Versus Triacylglycerol-Enriched Lipid Droplets

R. Ahrends, F. Kraemer, M. Teruel, 2014, PloS one.

Effect of muscle glycogen depletion on in vivo insulin action in man.

E. Ravussin, C. Bogardus, B. Vasquez, 1983, The Journal of clinical investigation.

Slc43a3 is a regulator of free fatty acid flux1

D. Bernlohr, Yiqiang Zhang, F. Kraemer, 2020, Journal of Lipid Research.

High dietary fructose induces a hepatic stress response resulting in cholesterol and lipid dysregulation.

S. Azhar, G. Allan, Glen L. Kelley, 2004, Endocrinology.

Tissue Specific Ablation of ACSL4 Results in Disturbed Steroidogenesis.

A. Greenberg, F. Kraemer, W. Shen, 2019, Endocrinology.

Anti‐hyperlipidaemic effects of synthetic analogues of nordihydroguaiaretic acid in dyslipidaemic rats

R. Parthasarathi, M. Inayathullah, J. Rajadas, 2018, British journal of pharmacology.

Nordihydroguaiaretic Acid, a Lignan from Larrea tridentata (Creosote Bush), Protects Against American Lifestyle-Induced Obesity Syndrome Diet–Induced Metabolic Dysfunction in Mice

M. Inayathullah, F. Kraemer, W. Shen, 2018, The Journal of Pharmacology and Experimental Therapeutics.

Gonadotropin receptors in plasma membranes of bovine corpus luteum. I. Effect of phospholipases on the binding of 125I-choriogonadotropin by membrane-associated and solubilized receptors.

K. Menon, S. Azhar, 1976, The Journal of biological chemistry.

The relationship between plasma glucose and insulin responses to oral glucose, LDL oxidation, and soluble intercellular adhesion molecule-1 in healthy volunteers.

G. Reaven, F. Abbasi, S. Azhar, 2000, Atherosclerosis.

Regulation of Expression and Function of Scavenger Receptor Class B, Type I (SR-BI) by Na+/H+ Exchanger Regulatory Factors (NHERFs)*

C. Yun, F. Kraemer, W. Shen, 2013, The Journal of Biological Chemistry.

Regulation of cholesterol responsive genes in ovary cells: impact of cholesterol delivery systems.

S. Medicherla, A. Cooper, S. Azhar, 1996, Biochemistry.

Masoprocol decreases rat lipolytic activity by decreasing the phosphorylation of HSL.

G. Reaven, F. Kraemer, M. Gowri, 2000, American journal of physiology. Endocrinology and metabolism.

Creosote bush-derived NDGA attenuates molecular and pathological changes in a novel mouse model of non-alcoholic steatohepatitis (NASH)

F. Kraemer, W. Shen, H. Dulay, 2019, Molecular and Cellular Endocrinology.

Differences in insulin-induced glucose uptake and enzyme activity in running rats.

W. Haskell, G. Reaven, C. Mondon, 1990, Journal of applied physiology.

Impact of Aging on Cholesterol Transport Protein Expression and Steroidogenesis in Rat Testicular Leydig Cells

W. Shen, S. Azhar, Zhi-Peng Sun, 2008 .

Altered responsiveness to alpha- and beta-adrenoceptor stimulation in hepatocytes cultured in defined medium.

G. Tsujimoto, B. Hoffman, A. Tsujimoto, 1986, Biochemical pharmacology.

Alpha 1 adrenergic receptor mediated polyphosphoinositide breakdown in DDT1-MF2 cells. Lack of evidence of desensitization after prolonged exposure to epinephrine.

J. Rosenbaum, B. Hoffman, S. Azhar, 1987, Biochemical pharmacology.

The adaptor protein GIPC1 stabilizes the scavenger receptor SR-B1 and increases its cholesterol uptake

R. Liu, W. Shen, Zhigang Guo, 2021, The Journal of biological chemistry.

Unique microtubules in luteal cells from superovulated rats.

S. Azhar, E. Reaven, C. Jensen, 1983, Journal of Ultrastructure Research.

Novel ABCA1 peptide agonists with antidiabetic action

F. Kraemer, W. Shen, J. Lagerstedt, 2019, Molecular and Cellular Endocrinology.

Pathogenesis of cholesteryl lipidosis of adrenocortical and ovarian interstitial cells in F344 rats caused by tricresyl phosphate and butylated triphenyl phosphate.

C. Brooks, C. Capen, J. Latendresse, 1993, Toxicology and applied pharmacology.

Effects of aging on cholesterol content and cholesterol-metabolizing enzymes in the rat adrenal gland.

S. Azhar, P. Popplewell, 1987, Endocrinology.

Desensitization of α1 Adrenoceptor‐Stimulated Glycogen Phosphorylase Activity in Vascular Smooth Muscle

G. Tsujimoto, B. Hoffman, A. Tsujimoto, 1989 .

Ovarian adenosine 3':5'-cyclic monophosphate-dependent protein kinase(s). Regulation by choriogonadotropin and lutropin in rat ovarian cells.

K. Menon, S. Azhar, M. R. Clark, 1976, The Biochemical journal.

Gonadotropin induced stimulation and desensitization of cyclic 3', 5' -adenosine monophosphate dependent protein kinase(s) in the rat ovary.

K. Menon, S. Azhar, C. Fanelli, 1978, Endocrine research communications.

Reconstitution of the lipoprotein cholesteryl ester transfer process using isolated rat ovary plasma membranes.

S. Azhar, E. Reaven, X. Shi, 1992, Biochemistry.

Receptor-mediated gonadotropin action in the ovary. Action of cytoskeletal element-disrupting agents on gonadotropin-induced steroidogenesis in rat luteal cells.

K. Menon, S. Azhar, 1981, Biochemical Journal.

Role of exogenous cholesterol in regulation of adrenal steroidogenesis in the rat.

G. Reaven, L. Verschoor, S. Azhar, 1982, The Journal of biological chemistry.

Masoprocol decreases serum triglyceride concentrations in rats with fructose-induced hypertriglyceridemia.

G. Reaven, M. Gowri, S. Azhar, 2000, Metabolism: clinical and experimental.

Age-dependent modulation of NF-kappaB expression in rat adrenal gland.

S. Azhar, S. Leers-sucheta, Rajeshwari Medicherla, 2002, Mechanisms of ageing and development.

Glucose Transporter (GLUT 4) Content and Insulin Receptor Kinase Activity in Muscles of the LA/N-cp Rat

J. Butte, S. Azhar, M. Kern, 1994, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Stimulation of lipoprotein receptors and role of lipoprotein and cellular cholesterol during gonadotropin-induced desensitization of steroidogenic response in luteinized rat ovary.

G. Reaven, S. Azhar, Y. D. Chen, 1983, The Journal of biological chemistry.

Evidence for Age-Related Changes in Pyridine Nucleotide Content of Isolated Rat Islets

G. Reaven, S. Azhar, E. Reaven, 1988, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Effect of okadaic acid on hepatocyte structure and function.

L. Tsai, S. Azhar, E. Reaven, 1993, Cellular & molecular biology research.

MicroRNA-122: a new player in the negative regulation of LH receptor expression by the LH receptor mRNA binding protein (LRBP).

S. Azhar, 2013, Endocrinology.

Epigenetic BET reader inhibitor apabetalone (RVX-208) counters proinflammatory aortic gene expression in a diet induced obesity mouse model and in human endothelial cells.

S. Wasiak, N. Wong, B. Rakai, 2022, Atherosclerosis.

A Novel Role of Salt-Inducible Kinase 1 (SIK1) in the Post-Translational Regulation of Scavenger Receptor Class B Type 1 Activity.

F. Kraemer, W. Shen, Zhigang Hu, 2015, Biochemistry.

Prolonged Activation of α1 Adrenoceptors Induces Downregulation of Protein Kinase C in Vascular Smooth Muscle

Zhuo-wei Hu, B. Hoffman, S. Azhar, 1992 .