C. Hewage

发表

Methyl ester of para-coumaric acid: antifungal principle of the rhizome of Costus speciosus.

V. Karunaratne, N. Adikaram, B. Bandara, 1988, Planta medica.

Antifungal activity of some medicinal plants of Sri Lanka

V. Karunaratne, N. Adikaram, B. Bandara, 1989 .

An antifungal chromene from Eupatorium riparium

V. Karunaratne, N. Adikaram, B. Bandara, 1992 .

Insecticidal activity of some medicinal plants of Sri Lanka

D. Wijesundara, V. Karunaratne, B. Bandara, 1997 .

Impact of the gliotoxin l-serine-O-sulphate on cellular metabolism in cultured rat astrocytes

L. Brennan, P. Alves, J. Malthouse, 2006, Neurochemistry International.

Gliotoxins disrupt alanine metabolism and glutathione production in C6 glioma cells: a 13C NMR spectroscopic study

L. Brennan, J. Malthouse, G. McBean, 2004, Neurochemistry International.

1H NMR spectroscopy as a tool to evaluate key metabolic functions of primary porcine hepatocytes after cryopreservation

P. Hayes, J. Parkinson, J. Plevris, 2002, NMR in biomedicine.

Coupled effect of salt and pH on proteins probed with NMR spectroscopy

J. Nielsen, Predrag Kukic, C. Hewage, 2013 .

Racemisation of N‐Fmoc phenylglycine under mild microwave‐SPPS and conventional stepwise SPPS conditions: attempts to develop strategies for overcoming this

M. Elsawy, C. Hewage, B. Walker, 2012, Journal of peptide science : an official publication of the European Peptide Society.

13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and γ-glutamyl cycle activity in a clonal pancreatic beta-cell line

L. Brennan, P. Newsholme, P. Flatt, 2003, Diabetologia.

NMR and Alanine Scan Studies of Glucose-dependent Insulinotropic Polypeptide in Water*

P. Flatt, J. Malthouse, J. Parker, 2006, Journal of Biological Chemistry.

A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line: metabolism of L-alanine is important to the regulation of insulin secretion.

L. Brennan, K. Brindle, P. Newsholme, 2002, Diabetes.

Prolonged L-alanine exposure induces changes in metabolism, Ca(2+) handling and desensitization of insulin secretion in clonal pancreatic beta-cells.

L. Brennan, P. Newsholme, P. Flatt, 2009, Clinical science.

In Vitro Activities of Synthetic Host Defense Propeptides Processed by Neutrophil Elastase against Cystic Fibrosis Pathogens

N. McElvaney, C. Greene, S. Cryan, 2011, Antimicrobial Agents and Chemotherapy.

Solution structure of a novel ETB receptor selective agonist ET1-21 [Cys(Acm)1,15, Aib3,11, Leu7] by nuclear magnetic resonance spectroscopy and molecular modelling.

J. Parkinson, I. Sadler, C. Hewage, 1999, The journal of peptide research : official journal of the American Peptide Society.

Development of ET(B) selective agonists: solution structure of a linear endothelin-1 analogue, ET-1 [Cys(Acm)(1,15), Ala3, Leu7, dAsp8, Aib11].

J. Parkinson, I. Sadler, C. Hewage, 1998, Journal of biomolecular structure & dynamics.

Solution conformation of an ETB selective agonist, ET‐1[Cys(Acm)1,15,Ala3,Leu7,Aib11], in CD3OH/H2O by 1H NMR and molecular modelling

Lu Jiang, J. Parkinson, I. Sadler, 1998 .

Antioxidant properties and quantitative UPLC-MS analysis of phenolic compounds from extracts of fenugreek (Trigonella foenum-graecum) seeds and bitter melon (Momordica charantia) fruit.

N. Brunton, T. Smyth, C. Hewage, 2013, Food chemistry.

Generation and contrasting gas-phase reactivity of 2-(2-alkenylpyrrol-1-yl)phenoxyl and thiophenoxyl radicals.

H. Mcnab, I. Sadler, C. Hewage, 2006, Organic & biomolecular chemistry.

A 13C-NMR study of azacryptand complexes.

J. Malthouse, G. G. Morgan, C. Hewage, 2014, Dalton transactions.

Structural and positional studies of the antimicrobial peptide brevinin‐1BYa in membrane‐mimetic environments

J. Conlon, C. Hewage, P. B. Timmons, 2019, Journal of peptide science : an official publication of the European Peptide Society.

Insights into conformation and membrane interactions of the acyclic and dicarba-bridged brevinin-1BYa antimicrobial peptides

J. Conlon, C. Hewage, P. B. Timmons, 2019, European Biophysics Journal.

APPTEST is a novel protocol for the automatic prediction of peptide tertiary structures

C. Hewage, P. B. Timmons, 2021, Briefings in bioinformatics.

Characterisation of Antimicrobial Extracts from Dandelion Root (Taraxacum officinale) Using LC‐SPE‐NMR

N. Brunton, T. Smyth, P. Mcloughlin, 2015, Phytotherapy research : PTR.

Investigating the potential of under-utilised plants from the Asteraceae family as a source of natural antimicrobial and antioxidant extracts.

N. Brunton, T. Smyth, C. Kelleher, 2014, Food chemistry.

Quantitative UPLC-MS/MS analysis of chlorogenic acid derivatives in antioxidant fractionates from dandelion (Taraxacum officinale) root

N. Brunton, T. Smyth, C. Hewage, 2015 .

Antioxidant properties and quantitative UPLC-MS/MS analysis of phenolic compounds in dandelion (Taraxacum officinale ) root extracts

N. Brunton, T. Smyth, C. Hewage, 2014 .

4-hydroxyphenylacetic acid derivatives of inositol from dandelion (Taraxacum officinale) root characterised using LC-SPE-NMR and LC-MS techniques.

N. Brunton, T. Smyth, P. Mcloughlin, 2014, Phytochemistry.

Biotransformation of halophenols using crude cell extracts of Pseudomonas putida F6

W. Duetz, K. E. O’ Connor, J. Malthouse, 2004, Applied Microbiology and Biotechnology.

ENNAVIA is a novel method which employs neural networks for antiviral and anti-coronavirus activity prediction for therapeutic peptides

C. Hewage, P. B. Timmons, 2021, Briefings Bioinform..

Conformation and membrane interaction studies of the potent antimicrobial and anticancer peptide palustrin-Ca

C. Hewage, P. B. Timmons, 2021, Scientific Reports.

ENNAVIA is an innovative new method which employs neural networks for antiviral and anti-coronavirus activity prediction for therapeutic peptides

C. Hewage, P. B. Timmons, 2021, bioRxiv.

Modification of chicken avian β-defensin-8 at positively selected amino acid sites enhances specific antimicrobial activity

D. Lynn, A. T. Lloyd, R. Higgs, 2007, Immunogenetics.

Investigation of the effects of sulfonylurea exposure on pancreatic beta cell metabolism

L. Brennan, P. Newsholme, P. Flatt, 2006, The FEBS journal.

Conformational, receptor interaction and alanine scan studies of glucose-dependent insulinotropic polypeptide.

J. Malthouse, F. O'Harte, C. Hewage, 2011, Biochimica et biophysica acta.

Conformational and molecular interaction studies of glucagon‐like peptide‐2 with its N‐terminal extracellular receptor domain

C. Hewage, K. Venneti, 2011, FEBS letters.

HAPPENN is a novel tool for hemolytic activity prediction for therapeutic peptides which employs neural networks

Patrick Brendan Timmons, Chandralal M. Hewage, C. Hewage, 2020, Scientific Reports.

An NMR study of alterations in [1- 13 C ]glucose metabolism in C6 glioma cells by gliotoxic amino acids

L. Brennan, J. Malthouse, G. McBean, 2003, Neurochemistry International.

Biological activity of some steam distillates from leaves of ten species of rutaceous plants.

V. Karunaratne, N. Adikaram, B. Bandara, 1990 .

Remeasuring HEWL pKa values by NMR spectroscopy: Methods, analysis, accuracy, and implications for theoretical pKa calculations

Damien Farrell, Helen Webb, Kaare Teilum, 2011, Proteins.

Oxyanion and tetrahedral intermediate stabilisation by subtilisin: detection of a new tetrahedral adduct.

J. Malthouse, N. Howe, C. Hewage, 2009, Biochimica et biophysica acta.

13C and 1H NMR Studies of Ionizations and Hydrogen Bonding in Chymotrypsin-Glyoxal Inhibitor Complexes*

J. Malthouse, Edward Spink, C. Hewage, 2007, Journal of Biological Chemistry.

Ionisations within a subtilisin-glyoxal inhibitor complex.

J. Malthouse, C. Hewage, Aleksandra Djurdjevic-Pahl, 2005, Biochimica et biophysica acta.

13C-NMR study of the inhibition of δ-chymotrypsin by a tripeptide-glyoxal inhibitor

C. Hewage, J. P. Malthouse, Aleksandra Djurdjevic-Pahl, 2002 .

Patterns of methyl and O-acetyl esterification in spinach pectins: new complexity.

K. Bailey, S. Fry, I. Sadler, 2002, Phytochemistry.

ENNAACT is a novel tool which employs neural networks for anticancer activity classification for therapeutic peptides.

Patrick Brendan Timmons, Chandralal M Hewage, C. Hewage, 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Glucagon receptor antagonist and GIP agonist combination for diet-induced obese mice.

N. Irwin, C. Hewage, F. O'Harte, 2016, The Journal of endocrinology.

Conformational and membrane interaction studies of the antimicrobial peptide alyteserin-1c and its analogue [E4K]alyteserin-1c.

J. Conlon, C. Hewage, Anusha P. Subasinghage, 2011, Biochimica et biophysica acta.

Metabolic and structural properties of human obestatin {1–23} and two fragment peptides

N. Irwin, P. Flatt, B. Green, 2010, Peptides.

NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1-30)amide.

J. Malthouse, J. Parker, V. Gault, 2004, Biochemical and biophysical research communications.

Design of ET(B) receptor agonists: NMR spectroscopic and conformational studies of ET7-21[Leu7, Aib11, Cys(Acm)15].

J. Parkinson, I. Sadler, C. Hewage, 2002, Protein engineering.

A linear endothelin-1 analogue: solution structure of ET-1[Aib1,3,11,15, Nle7] by nuclear magnetic resonance spectroscopy and molecular modelling

Lu Jiang, J. Parkinson, I. Sadler, 1999, Neurochemistry International.

Structural Aspects of Gut Peptides with Therapeutic Potential for Type 2 Diabetes

C. Hewage, K. Venneti, Kalyana C. Venneti, 2013, ChemMedChem.

α-d-Mannopyranosyl-(1→4)-α-d-glucuronopyranosyl-(1→2)-myo-inositol, a new and unusual oligosaccharide from cultured rose cells

S. Fry, I. Sadler, C. Hewage, 1999 .

HAPPENN is a novel tool for hemolytic activity prediction for therapeutic peptides which employs neural networks

C. Hewage, P. B. Timmons, 2020, Scientific Reports.

Solution structure determination of endothelin‐1 in methanol/water by NMR and molecular modelling methods

J. Parkinson, I. Sadler, C. Hewage, 1997, Journal of peptide science : an official publication of the European Peptide Society.

Identification of Determinants of Glucose-Dependent Insulinotropic Polypeptide Receptor That Interact with N-Terminal Biologically Active Region of the Natural Ligand

T. Yaqub, I. Tikhonova, C. Escrieut, 2010, Molecular Pharmacology.

Development of potent anti-infective agents from Silurana tropicalis: conformational analysis of the amphipathic, alpha-helical antimicrobial peptide XT-7 and its non-haemolytic analogue [G4K]XT-7.

J. Conlon, C. Hewage, Anusha P. Subasinghage, 2010, Biochimica et biophysica acta.

Conformational analysis of the broad-spectrum antibacterial peptide, ranatuerin-2CSa: identification of a full length helix-turn-helix motif.

J. Conlon, C. Hewage, Anusha P. Subasinghage, 2008, Biochimica et biophysica acta.

The bioactive conformation of glucose‐dependent insulinotropic polypeptide by NMR and CD spectroscopy

J. Malthouse, C. Hewage, F. O'Harte, 2007, Proteins.

Determination of the structure of tetrahedral transition state analogues bound at the active site of chymotrypsin using 18O and 2H isotope shifts in the 13C NMR spectra of glyoxal inhibitors.

J. Malthouse, Edward Spink, C. Hewage, 2007, Biochemistry.

NMR study of the inhibition of pepsin by glyoxal inhibitors: mechanism of tetrahedral intermediate stabilization by the aspartyl proteases.

J. Malthouse, C. Hewage, Sonya Cosgrove, 2007, Biochemistry.

13C-NMR study of the inhibition of delta-chymotrypsin by a tripeptide-glyoxal inhibitor.

J. Malthouse, C. Hewage, Aleksandra Djurdjevic-Pahl, 2002, The Biochemical journal.

Solution structure determination of endothelin‐1 in methanol/water by NMR and molecular modelling methods

J. Parkinson, I. Sadler, C. Hewage, 1997, Journal of peptide science : an official publication of the European Peptide Society.

A 13C-NMR study of the inhibition of papain by a dipeptide-glyoxal inhibitor.

J. Lowther, C. Hewage, J. P. Malthouse, 2002, The Biochemical journal.

Conformational analysis of an EP24.15 inhibitor by NMR and molecular modelling

Rosaleen J. Anderson, B. P. Clark, S. Mackay, 2006, Letters in Peptide Science.

Biophysical study of the structure and dynamics of the antimicrobial peptide maximin 1

C. Hewage, P. B. Timmons, 2021, Journal of peptide science : an official publication of the European Peptide Society.

NMR model structure of the antimicrobial peptide maximin 3

C. Hewage, P. B. Timmons, Silvia Benetti, 2019, European Biophysics Journal.

Racemisation of N‐Fmoc phenylglycine under mild microwave‐SPPS and conventional stepwise SPPS conditions: attempts to develop strategies for overcoming this

M. Elsawy, C. Hewage, B. Walker, 2012, Journal of peptide science : an official publication of the European Peptide Society.

Nα- and Nε-d-galacturonoyl-l-lysine amides: Properties and possible occurrence in plant cell walls

S. Fry, I. Sadler, C. Hewage, 1998 .