Chin-Yuan Chang

发表

Terpene synthases in disguise: enzymology, structure, and opportunities of non-canonical terpene synthases.

J. Rudolf, Chin-Yuan Chang, 2020, Natural product reports.

Crystal Structure of SgcJ, An NTF2-Like Superfamily Protein Involved in Biosynthesis of the 9-Membered Enediyne Antitumor Antibiotic C-1027

B. Shen, G. Phillips, A. Joachimiak, 2016, The Journal of Antibiotics.

Structure of the ent-Copalyl Diphosphate Synthase PtmT2 from Streptomyces platensis CB00739, a Bacterial Type II Diterpene Synthase

B. Shen, G. Phillips, A. Joachimiak, 2016, Journal of the American Chemical Society.

Expression and characterization of the biofilm‐related and carnosine‐hydrolyzing aminoacylhistidine dipeptidase from Vibrio alginolyticus

Chin-Yuan Chang, Tung-Kung Wu, Yi-Chin Chen, 2008, The FEBS journal.

Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme

B. Shen, G. Phillips, A. Joachimiak, 2018, Nature Chemical Biology.

Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus

B. Shen, G. Phillips, A. Joachimiak, 2016, Biochemistry.

Efficient and Reversible Catalysis of Formic Acid‐Carbon Dioxide Cycle Using Carbamate‐Substituted Ruthenium‐Dithiolate Complexes

Jen-Shiang K. Yu, Ya-Ting Kao, Chin-Yuan Chang, 2021, ChemCatChem.

Purification, crystallization and preliminary X-ray analysis of an aminoacylhistidine dipeptidase (PepD) from Vibrio alginolyticus.

Chun Jung Chen, Chin-Yuan Chang, Tung-Kung Wu, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystal structure of the α-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer

Zhengren Xu, Chin-Yuan Chang, Encheng Lin, 2022, Frontiers in Chemistry.

Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexes.

Tsung-Lin Li, Chang-Jer Wu, Syue-Yi Lyu, 2014, Acta crystallographica. Section D, Biological crystallography.

Structural determination of an antibody that specifically recognizes polyethylene glycol with a terminal methoxy group

Y. Jong, T. Cheng, S. Roffler, 2022, Communications Chemistry.

Nickel hexacyanoferrate multilayers on functionalized mesoporous silica supports for selective sorption and sensing of cesium

L. Chau, J. Liao, Chin-Yuan Chang, 2008 .

Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892.

B. Shen, G. Phillips, A. Joachimiak, 2015, Biochemistry.

Structure-guided product determination of the bacterial type II diterpene synthase Tpn2

J. Rudolf, Chin-Yuan Chang, Ya-Lin Lin, 2022, Communications Chemistry.

Characterization of Enzymes Catalyzing the Formation of the Nonproteinogenic Amino Acid l-Dap in Capreomycin Biosynthesis.

Zhengren Xu, Chin-Yuan Chang, Tung-Kung Wu, 2020, Biochemistry.

Comparative Studies of the Biosynthetic Gene Clusters for Anthraquinone-Fused Enediynes Shedding Light into the Tailoring Steps of Tiancimycin Biosynthesis.

B. Shen, Xiaohui Yan, C. Rader, 2018, Organic letters.

Discovery of Alternative Producers of the Enediyne Antitumor Antibiotic C-1027 with High Titers.

B. Shen, Xiaohui Yan, Xiangcheng Zhu, 2018, Journal of natural products.

Genome Mining of Micromonospora yangpuensis DSM 45577 as a Producer of an Anthraquinone-Fused Enediyne.

B. Shen, Xiaohui Yan, C. Rader, 2017, Organic letters.

Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis

B. Shen, G. Phillips, A. Joachimiak, 2017, ACS omega.

Characterization of the Ketosynthase and Acyl Carrier Protein Domains at the LnmI Nonribosomal Peptide Synthetase–Polyketide Synthase Interface for Leinamycin Biosynthesis

B. Shen, Guohui Pan, Yong Huang, 2016, Organic letters.

Genome mining and biosynthesis of kitacinnamycins as a STING activator† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc00815b

Cheng Liu, H. Ge, Jiapeng Zhu, 2019, Chemical science.

The Mesomeric Effect of Thiazolium on non-Kekulé Diradicals in Pichia stipitis Transketolase.

Tsung-Lin Li, Chang-Jer Wu, N. Hsu, 2018, Angewandte Chemie.

Polystyrene monolithic column functionalized with copper-iminodiacetate complex as a stationary phase for open tubular capillary electrochromatography.

Chuen‐Ying Liu, Chin-Yuan Chang, Shiu-Chun Chuang, 2004, Journal of chromatography. A.

Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase.

M. Tsai, Tsung-Lin Li, Chang-Jer Wu, 2014, Acta crystallographica. Section D, Biological crystallography.

PokMT1 from the Polyketomycin Biosynthetic Machinery of Streptomyces diastatochromogenes Tü6028 Belongs to the Emerging Family of C-Methyltransferases That Act on CoA-Activated Aromatic Substrates.

B. Shen, Geoff P. Horsman, A. Bechthold, 2018, Biochemistry.

Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function.

B. Shen, M. Ma, J. Rudolf, 2017, Natural product reports.

Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus.

M. Tsai, Tsung-Lin Li, Chang-Jer Wu, 2014, Journal of the American Chemical Society.

Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms.

M. Tsai, Tsung-Lin Li, Chang-Jer Wu, 2014, Angewandte Chemie.

Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions

Tsung-Lin Li, N. Hsu, Yi-Shan Li, 2022, ACS Catalysis.

Engineered photo-chemical therapeutic nanocomposites provide effective antibiofilm and microbicidal activities against bacterial infections in porous devices.

Yu-Hsiang Lee, Chin-Yuan Chang, Chen-Chih Chiu, 2021, Biomaterials science.

Kinetics of an inverse temperature transition process and its application on supported lipid bilayers

Chin-Yuan Chang, 2010 .

Crystal Structure and Mutational Analysis of Aminoacylhistidine Dipeptidase from Vibrio alginolyticus Reveal a New Architecture of M20 Metallopeptidases*

Chun-Jung Chen, Chin-Yuan Chang, Cheng-Hsiang Chang, 2010, The Journal of Biological Chemistry.

Characterization of TnmH as an O-Methyltransferase Revealing In-sights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy to Prepare Antibody-Tiancimycin Conjugates.

B. Shen, Xiaohui Yan, C. Rader, 2020, Journal of medicinal chemistry.

Multiple Pleomorphic Tetramers of Thermostable Direct Hemolysin from Grimontia hollisae in Exerting Hemolysis and Membrane Binding

B. Yip, Chin-Yuan Chang, Tung-Kung Wu, 2019, Scientific Reports.

Pregnenolonyl-α-glucoside exhibits marked anti-cancer and CYP17A1 enzymatic inhibitory activities.

Chin-Yuan Chang, Tung-Kung Wu, Sheng-Cih Huang, 2020, Chemical communications.

Crystal Structure and Inhibition Studies of Transglutaminase from Streptomyces mobaraense*

Chin-Yuan Chang, Cheng-Hsiang Chang, Tung-Kung Wu, 2010, The Journal of Biological Chemistry.

Dual-Mechanism Confers Self-Resistance to the Antituberculosis Antibiotic Capreomycin.

Tsung-Lin Li, Zhengren Xu, N. Hsu, 2022, ACS chemical biology.

Resistance to Enediyne Antitumor Antibiotics by Sequestration.

B. Shen, G. Phillips, A. Joachimiak, 2018, Cell chemical biology.

Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway.

Mitchell D. Miller, B. Shen, G. Phillips, 2018, ACS chemical biology.

N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry

T. Dairi, Yasushi Ogasawara, Y. Hamano, 2023, Nature communications.

Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexes.

Tsung-Lin Li, Chang-Jer Wu, Syue-Yi Lyu, 2014, Acta crystallographica. Section D, Biological crystallography.

Crystal Structure and Mutational Analysis of Aminoacylhistidine Dipeptidase from Vibrio alginolyticus Reveal a New Architecture of M20 Metallopeptidases*

Chun-Jung Chen, Chin-Yuan Chang, Cheng-Hsiang Chang, 2010, The Journal of Biological Chemistry.