Weiming Chen

发表

Structure-Activity Relationships and X-ray Structures Describing the Selectivity of Aminopyrazole Inhibitors for c-Jun N-terminal Kinase 3 (JNK3) over p38*

P. Lograsso, J. Habel, Y. Ling, 2009, Journal of Biological Chemistry.

Design and synthesis of 1-aryl-5-anilinoindazoles as c-Jun N-terminal kinase inhibitors.

M. Cameron, T. Kamenecka, Y. Shin, 2013, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of novel quinazolines as potent and brain-penetrant c-jun N-terminal kinase (JNK) inhibitors.

P. Lograsso, M. Cameron, Y. Ling, 2011, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of 4-(pyrazol-3-yl)-pyridines as novel c-jun N-terminal kinase inhibitors.

P. Lograsso, M. Cameron, Y. Ling, 2011, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of 2-phenoxypyridines as novel c-Jun N-terminal kinase inhibitors.

M. Cameron, T. Kamenecka, Claudia H. Ruiz, 2011, Bioorganic & medicinal chemistry letters.

Development of an HTS-compatible assay for the discovery of ASK1 signalosome inhibitors using alphascreen technology.

T. Spicer, P. Hodder, E. Sturchler, 2014, Assay and drug development technologies.

Discovery of bufadienolides as a novel class of ClC-3 chloride channel activators with antitumor activities.

Hai-bin Luo, W. Ye, Ying Wang, 2013, Journal of medicinal chemistry.

Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors.

P. Lograsso, J. Habel, Y. Ling, 2009, Bioorganic & medicinal chemistry letters.

3,5-Disubstituted quinolines as novel c-Jun N-terminal kinase inhibitors.

P. Lograsso, J. Habel, Y. Ling, 2007, Bioorganic & medicinal chemistry letters.

Homotypic dimerization of a maltose kinase for molecular scaffolding

Z. Rao, Xuemei Li, N. Shaw, 2014, Scientific Reports.

Expression, purification, crystallization and preliminary X-ray diffraction analysis of the C-terminal NHL domain of human TRIM2.

Xuemei Li, Jun Li, Yuanfang Dong, 2014, Acta crystallographica. Section F, Structural biology communications.

Synthesis, biological evaluation, X-ray structure, and pharmacokinetics of aminopyrimidine c-jun-N-terminal kinase (JNK) inhibitors.

P. Lograsso, J. Habel, M. Cameron, 2010, Journal of medicinal chemistry.

Development of an HTS-Compatible Assay for the Discovery of Ulk1 Inhibitors

J. Cleveland, L. H. Rosenberg, Derek R Duckett, 2015, Journal of biomolecular screening.

Synthesis and SAR of 2,4-diaminopyrimidines as potent c-jun N-terminal kinase inhibitors

M. Cameron, Y. Ling, T. Kamenecka, 2012 .

Benzothiazoles as Rho-associated kinase (ROCK-II) inhibitors.

P. Lograsso, S. Schürer, J. Pocas, 2009, Bioorganic & medicinal chemistry letters.

The a3 Isoform of the 100-kDa V-ATPase Subunit Is Highly but Differentially Expressed in Large (≥10 Nuclei) and Small (≤5 Nuclei) Osteoclasts*

Yeqi Yao, J. Heersche, Hesheng Yu, 2003, Journal of Biological Chemistry.

Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties.

J. Cleveland, S. Schürer, M. Cameron, 2013, Bioorganic & medicinal chemistry letters.

Synthesis, docking studies and antitumor activity of phenanthroimidazole derivatives as promising c-myc G-quadruplex DNA stabilizers.

Wenjie Mei, Weiming Chen, Qiong Wu, 2020, Bioorganic chemistry.

Stress-induced nuclear import of apoptosis signal-regulating kinase 1 is mediated by karyopherin α2/β1 heterodimer.

E. Sturchler, P. McDonald, D. Feurstein, 2013, Biochimica et biophysica acta.

Therapeutic targeting of casein kinase 1δ in breast cancer

Jenny C. Chang, M. Fallahi, J. Cleveland, 2015, Science Translational Medicine.

Synthesis and SAR of novel isoxazoles as potent c-jun N-terminal kinase (JNK) inhibitors.

P. Lograsso, M. Cameron, Y. Ling, 2014, Bioorganic & medicinal chemistry letters.

Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties.

J. Cleveland, S. Schürer, M. Cameron, 2013, Bioorganic & medicinal chemistry letters.